General Information of the Compound
| Compound ID |
CP0015827
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| Compound Name |
(2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
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| Synonyms |
(2E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-(PHENYLMETHYL)-2-PROPENAMIDE
(2E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
(E)-N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
133550-30-8
134036-52-5
AG 490
AG-490
AG-490 (Tyrphostin B42)
AG490
CHEMBL56543
N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide
SMR001230665
Tyrphostin AG 490
Tyrphostin AG490
Tyrphostin B42
alpha-Cyano-(3,4-dihydroxy)-N-benzylcinnamide
tyrphostin AG-490
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| Structure |
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| Formula |
C17H14N2O3
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| Molecular Weight |
294.31
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| Canonical SMILES |
Oc1ccc(\C=C(/C#N)C(=O)NCc2ccccc2)cc1O
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| InChI |
InChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
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| InChIKey |
TUCIOBMMDDOEMM-RIYZIHGNSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Clinical Information about the Compound