General Information of the Cell Line
Cell Line ID
CL001061
Cell Line Name
PC-2 [Human pancreatic carcinoma China]
Synonyms
PC2
Category
Cancer cell line
Organism
Homo sapiens (Human)
Tissue Information
Omentum
Disease
Pancreatic ductal adenocarcinoma (NCIt: C9120)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01201, Hepatocyte growth factor receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0286414
 Compound Info 
2-chloro-4-[3-[(4-hydroxyphenyl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-N-methylbenzamide
   Show/Hide
C20H16ClN5O2
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0296605
 Compound Info 
4-[[6-(4-methylthiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]phenol
   Show/Hide
C17H14N4OS
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0938836
 Compound Info 
7-methoxy-4-((6-(3-methylisothiazol-5-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
   Show/Hide
C16H13N5OS
  1
1
IC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0253093
 Compound Info 
2-fluoro-4-[3-[(4-hydroxyphenyl)methyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-N-methylbenzamide
   Show/Hide
C20H16FN5O2
  1
1
IC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0333770
 Compound Info 
4-[(6-thiophen-2-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol
   Show/Hide
C16H12N4OS
  1
1
IC50 = 6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0087079
 Compound Info 
7-methoxy-4-{[6-(3,4,5-trifluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}quinoline
   Show/Hide
C22H14F3N5O2
  1
1
IC50 = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0096228
 Compound Info 
4-{[6-(3,5-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline
   Show/Hide
C22H15F2N5O2
  1
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0745157
 Compound Info 
4-(3-((7-methoxyquinolin-4-yloxy)methyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-Nmethylbenzamide
   Show/Hide
C20H17N5O2
  1
1
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0303862
 Compound Info 
4-{[6-(3-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline
   Show/Hide
C22H16FN5O2
  1
1
IC50 = 20 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0191798
 Compound Info 
4-{[6-(3,4-difluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline
   Show/Hide
C22H15F2N5O2
  1
1
IC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0253094
 Compound Info 
4-[(6-thiophen-3-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol
   Show/Hide
C16H12N4OS
  1
1
IC50 = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0191528
 Compound Info 
4-{[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline
   Show/Hide
C22H16FN5O2
  1
1
IC50 = 42 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0148189
 Compound Info 
7-methoxy-4-({6-phenyl-[1,2,4]triazolo[4,3-a]pyridazin-3-yl}methoxy)quinoline
   Show/Hide
C22H17N5O2
  1
1
IC50 = 46 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0266869
 Compound Info 
4-[[6-(furan-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]phenol
   Show/Hide
C16H12N4O2
  1
1
IC50 = 132 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0222503
 Compound Info 
4-{[6-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline
   Show/Hide
C22H16FN5O2
  1
1
IC50 = 400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Omentum)
Cell Line Name Organism Disease
OV-2008
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
ME-180
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma
2008/MRP1
 Cell Line Info 
Homo sapiens (Human) Human papillomavirus-related cervical squamous cell carcinoma