Brief Information of the Compound and Protein
Compound Name
7-methoxy-4-((6-(3-methylisothiazol-5-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline
    Show/Hide
PubChem ID
CID: 44576917
Canonical SMILES
Cc1cc(-c2ccc3nnc(Cc4ccc(O)cc4)n3n2)sn1
    Show/Hide
Compound Formula C16H13N5OS
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001061 PC-2 [Human pancreatic carcinoma China] Homo sapiens (Human)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM