Brief Information of the Compound and Protein
Compound Name
4-{[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridazin-3-yl]methoxy}-7-methoxyquinoline
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PubChem ID
CID: 24864822
SID: 50097516
Canonical SMILES
COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc(F)cc3)ccnc2c1
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Compound Formula C22H16FN5O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001061 PC-2 [Human pancreatic carcinoma China] Homo sapiens (Human)  1
1
IC50 = 42 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM