Brief Information of the Compound and Protein
Compound Name
4-[(6-thiophen-3-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]phenol
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PubChem ID
CID: 44576915
Canonical SMILES
Oc1ccc(Cc2nnc3ccc(nn23)-c2ccsc2)cc1
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Compound Formula C16H12N4OS
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001061 PC-2 [Human pancreatic carcinoma China] Homo sapiens (Human)  1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4 nM