General Information of the Cell Line
Cell Line ID
CL000367
Cell Line Name
AtT-20
Synonyms
AtT 20
ATT-20
AtT20
Category
Cancer cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_2300
Tissue Information
Pituitary gland
Disease
Mouse pituitary gland neoplasms (NCIt: C24037)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01588, Corticotropin-releasing factor receptor 1
Compound ID Compound Name Compound Formula
CP0478377
2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methyl-N,N-dipropylpyrimidin-5-amine
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C20H28ClN3O3
 1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CP0486463
2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methyl-5-(pentan-3-yloxy)pyrimidine
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C19H25ClN2O4
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0453236
1-(2-methoxy-4,6-dimethylphenyl)-3-methyl-N,N-dipropylisoquinolin-4-amine
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C25H32N2O
 2
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
2
Ki = 12 nM
   TI
   LI
   LO
   TS
CP0486464
4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methyl-5-(pentan-3-yloxy)pyrimidine
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C20H28N2O3
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0471135
1-(2,4-bis(2,2-difluoroethyl)-6-methoxyphenyl)-3-methyl-N,N-dipropylisoquinolin-4-amine
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C27H32F4N2O
 1
1
Ki = 22 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Pituitary gland)
Cell Line Name Organism Disease
GH4C1 Rattus norvegicus (Rat) Rat pituitary gland neoplasm
GH3 Rattus norvegicus (Rat) Rat pituitary gland neoplasm
MMQ Rattus norvegicus (Rat) Rat pituitary gland neoplasm
LbetaT2 Mus musculus (Mouse) -