Brief Information of the Compound and Protein
Compound Name
2-(4-chloro-2,6-dimethoxyphenyl)-4-methoxy-6-methyl-N,N-dipropylpyrimidin-5-amine
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PubChem ID
CID: 44587375
Canonical SMILES
CCCN(CCC)c1c(C)nc(nc1OC)-c1c(OC)cc(Cl)cc1OC
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Compound Formula C20H28ClN3O3
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000367 AtT-20 Mus musculus (Mouse)  1
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  1
1
Ki = 2 nM
   TI
   LI
   LO
   TS