| Compound ID |
Compound Name |
Compound Formula |
|
CP0210909
|
(2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]-3-(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1H-imidazol-2-yl)propan-2-ol
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|
C20H18F6N4O
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
|
CP0467436
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-2,2-dimethylpropanamide
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|
C26H34N6O
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0373810
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-2-methylpropanamide
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|
C25H32N6O
|
1
|
| 1 |
EC50 = 99 nM
|
|
|
|
CP0373811
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)propanamide
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|
C24H30N6O
|
1
|
| 1 |
EC50 = 123 nM
|
|
|
|
CP0401371
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)acetamide
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|
C23H28N6O
|
1
|
| 1 |
EC50 = 129 nM
|
|
|
|
CP0373809
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-2,2-dimethylbutanamide
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|
C27H36N6O
|
1
|
| 1 |
EC50 = 212 nM
|
|
|
|
CP0391006
|
7-(2-chlorobenzyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C21H25ClN6
|
1
|
| 1 |
EC50 = 342 nM
|
|
|
|
CP0373052
|
5-(Piperidin-1-yl)-7-(pyridin-2-ylmethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C20H25N7
|
1
|
| 1 |
EC50 = 346 nM
|
|
|
|
CP0390998
|
7-Benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine
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|
C21H26N6
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0411227
|
7-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C22H26N6O2
|
1
|
| 1 |
EC50 = 402 nM
|
|
|
|
CP0407113
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)cyclopentanecarboxamide
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|
C27H34N6O
|
1
|
| 1 |
EC50 = 413 nM
|
|
|
|
CP0430795
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-3,3-dimethylbutanamide
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|
C27H36N6O
|
1
|
| 1 |
EC50 = 433 nM
|
|
|
|
CP0435128
|
7-benzyl-N-ethyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C23H30N6
|
1
|
| 1 |
EC50 = 471 nM
|
|
|
|
CP0400203
|
7-benzyl-5-(4-fluoropiperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C21H25FN6
|
1
|
| 1 |
EC50 = 481 nM
|
|
|
|
CP0406802
|
7-benzyl-N-neopentyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C26H36N6
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0435127
|
1-(1-amino-7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-3-yl)ethanone
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|
C23H28N6O
|
1
|
| 1 |
EC50 = 759 nM
|
|
|
|
CP0373534
|
7-benzyl-5-(4-methylpiperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C22H28N6
|
1
|
| 1 |
EC50 = 854 nM
|
|
|
|
CP0373054
|
7-benzyl-5-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C20H24N6
|
1
|
| 1 |
EC50 = 965 nM
|
|
|
|
CP0411226
|
7-neopentyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C19H30N6
|
1
|
| 1 |
EC50 = 1057 nM
|
|
|
|
CP0417666
|
5-(azepan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C22H28N6
|
1
|
| 1 |
EC50 = 1442 nM
|
|
|
|
CP0401375
|
7-benzyl-5-morpholino-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C20H24N6O
|
1
|
| 1 |
EC50 = 3557 nM
|
|
|
|
CP0373051
|
7-[(4-fluorophenyl)methyl]-5-piperidin-1-yl-2,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C21H25FN6
|
1
|
| 1 |
EC50 = 3859 nM
|
|
|
|
CP0373049
|
7-benzyl-3-methyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C22H28N6
|
1
|
| 1 |
EC50 = 6056 nM
|
|
|
|
CP0391001
|
7-benzyl-N5-isopropyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
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|
C19H24N6
|
1
|
| 1 |
EC50 = 7652 nM
|
|
|
|
CP0390999
|
7-phenethyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C22H28N6
|
1
|
| 1 |
EC50 = 7906 nM
|
|
|
|
CP0504256
|
7-benzyl-N5,N5-dimethyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
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|
C18H22N6
|
1
|
| 1 |
EC50 = 8954 nM
|
|
|
|
CP0373048
|
7-benzyl-5-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C21H27N7
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0373050
|
5-(piperidin-1-yl)-7-(3-(trifluoromethyl)benzyl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C22H25F3N6
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0373053
|
7-benzyl-N5-phenyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
Show/Hide
|
C22H22N6
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
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CP0373056
|
7-(4-methoxybenzyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C22H28N6O
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0373057
|
7-benzyl-N5-cyclohexyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
Show/Hide
|
C22H28N6
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0391000
|
7-(cyclohexylmethyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C21H32N6
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
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CP0401372
|
7-isobutyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C18H28N6
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
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CP0417669
|
7-benzyl-5-(piperazin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C20H25N7
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
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CP0428233
|
5-(azocan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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|
C23H30N6
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
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CP0504251
|
7-(4-Fluorobenzoyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine
Show/Hide
|
C21H23FN6O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
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CP0915983
|
5-(Piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine di hydrochloride
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|
C14H21ClN6
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
