| Compound ID |
Compound Name |
Compound Formula |
|
CP0864138
|
(R)-4-((9-Chloro-7-(5-fluoro-1H-indol-1-yl)-3-methyl-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)methyl)pyridin-2(1H)-one
Show/Hide
|
C24H21ClFN3O2
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 10 nM
|
|
|
|
CP0088963
|
4-[[9-chloro-7-(5-fluoroindol-1-yl)-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methyl]-1H-pyridin-2-one
Show/Hide
|
C23H19ClFN3O2
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0849232
|
(R)-4-((7-(Benzo[b]thiophen-3-yl)-9-chloro-3-methyl-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)methyl)pyridin-2(1H)-one
Show/Hide
|
C24H21ClN2O2S
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0072691
|
4-[[7-(1-benzothiophen-3-yl)-9-chloro-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]methyl]-1H-pyridin-2-one
Show/Hide
|
C23H19ClN2O2S
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0651926
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(pyrimidin-5-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C23H21N3O2S
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 80 nM
|
|
|
|
CP0456264
|
7-(5-chloro-2,3-dihydroindol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H24ClN3O2
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
|
CP0919767
|
7-(5-Fluoro-1H-indol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C24H22FN3O2
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
IC50 = 90 nM
|
|
|
|
CP0376160
|
7-(3-chloroindol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H22ClN3O2
|
2
|
| 1 |
IC50 = 60 nM
|
|
|
| 2 |
IC50 = 900 nM
|
|
|
|
CP0072690
|
7-(1-benzothiophen-3-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H22N2O2S
|
2
|
| 1 |
IC50 = 70 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
|
CP0431712
|
7-(5-chloroindol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H22ClN3O2
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 700 nM
|
|
|
|
CP0769293
|
7-(Benzo[b]thiophen-3-yl)-9-chloro-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C23H19ClN2OS
|
2
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 2500 nM
|
|
|
|
CP0481584
|
1-[9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepin-7-yl]indole-5-carbonitrile
Show/Hide
|
C25H22N4O2
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0667402
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(4-(methylsulfonyl)-benzyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C26H25NO4S2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0674612
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-((6-methoxypyridin-3-yl)methyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C25H24N2O3S
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 1500 nM
|
|
|
|
CP0694102
|
3-((7-(Benzo[b]thiophen-3-yl)-9-methoxy-2,3-dihydrobenzo-[f][1,4]oxazepin-4(5H)-yl)methyl)benzonitrile
Show/Hide
|
C26H22N2O2S
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
|
CP0689002
|
5-((7-(Benzo[b]thiophen-3-yl)-9-methoxy-2,3-dihydrobenzo-[f][1,4]oxazepin-4(5H)-yl)methyl)pyridin-2-ol
Show/Hide
|
C24H22N2O3S
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 500 nM
|
|
|
|
CP0707842
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-((2-methoxypyridin-3-yl)methyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C25H24N2O3S
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 1100 nM
|
|
|
|
CP0762119
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(pyridin-4-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C24H22N2O2S
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 900 nM
|
|
|
|
CP0846792
|
7-(Benzo[b]thiophen-3-yl)-9-methyl-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C24H22N2OS
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
|
CP0504822
|
7-indol-1-yl-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H23N3O2
|
2
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
|
CP0891665
|
9-Methoxy-7-(naphthalen-1-yl)-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C26H24N2O2
|
2
|
| 1 |
IC50 = 300 nM
|
|
|
| 2 |
IC50 = 2500 nM
|
|
|
|
CP0382510
|
7-(1,2-benzothiazol-3-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C23H21N3O2S
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 600 nM
|
|
|
|
CP0433769
|
7-(4-chloroindol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H22ClN3O2
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 = 3300 nM
|
|
|
|
CP0684546
|
4-((7-(Benzo[b]thiophen-3-yl)-9-methoxy-2,3-dihydrobenzo-[f][1,4]oxazepin-4(5H)-yl)methyl)benzonitrile
Show/Hide
|
C26H22N2O2S
|
2
|
| 1 |
IC50 = 600 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0694103
|
Methyl4-((7-(Benzo[b]thiophen-3-yl)-9-methoxy-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)methyl)benzoate
Show/Hide
|
C27H25NO4S
|
2
|
| 1 |
IC50 = 600 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0407760
|
7-(3-chlorophenyl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C22H21ClN2O2
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 = 1900 nM
|
|
|
|
CP0689003
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(pyridin-2-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C24H22N2O2S
|
2
|
| 1 |
IC50 = 700 nM
|
|
|
| 2 |
IC50 = 3000 nM
|
|
|
|
CP0410761
|
7-(6-chloroindol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H22ClN3O2
|
2
|
| 1 |
IC50 = 800 nM
|
|
|
| 2 |
IC50 = 4000 nM
|
|
|
|
CP0534265
|
9-methoxy-7-(1-methylindol-3-yl)-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C25H25N3O2
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 = 2500 nM
|
|
|
|
CP0875363
|
7-(Benzo[b]thiophen-3-yl)-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C23H20N2OS
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0919773
|
7-(Benzo[b]thiophen-3-yl)-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-9-ol
Show/Hide
|
C23H20N2O2S
|
2
|
| 1 |
IC50 = 1500 nM
|
|
|
| 2 |
IC50 = 3800 nM
|
|
|
|
CP0908331
|
8-(Benzo[b]thiophen-3-yl)-2-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepine
Show/Hide
|
C24H22N2S
|
2
|
| 1 |
IC50 = 1600 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0718981
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(4-methoxybenzyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C26H25NO3S
|
2
|
| 1 |
IC50 = 1800 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0447840
|
7-(1H-indol-3-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H23N3O2
|
2
|
| 1 |
IC50 = 2700 nM
|
|
|
| 2 |
IC50 = 3000 nM
|
|
|
|
CP0944519
|
7-(Benzo[b]thiophen-2-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C24H22N2O2S
|
2
|
| 1 |
IC50 = 2800 nM
|
|
|
| 2 |
IC50 = 4800 nM
|
|
|
|
CP0865565
|
7-(Benzo[b]thiophen-3-yl)-1-methyl-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
Show/Hide
|
C24H23N3S
|
2
|
| 1 |
IC50 = 4000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0495379
|
7-(7-chloroindol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C24H22ClN3O2
|
2
|
| 1 |
IC50 = 5600 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0908415
|
7-(Benzo[b]thiophen-3-yl)-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
Show/Hide
|
C23H21N3S
|
2
|
| 1 |
IC50 = 6000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0444657
|
7-(benzimidazol-1-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C23H22N4O2
|
2
|
| 1 |
IC50 = 6400 nM
|
|
|
| 2 |
IC50 = 15000 nM
|
|
|
|
CP0407759
|
7-(4-chlorophenyl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C22H21ClN2O2
|
2
|
| 1 |
IC50 = 10000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0674611
|
7-(Benzo[b]thiophen-3-yl)-4-benzyl-9-methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C25H23NO2S
|
2
|
| 1 |
IC50 = 10000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0398178
|
7-(2-chlorophenyl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C22H21ClN2O2
|
2
|
| 1 |
IC50 = 12000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0456267
|
9-methoxy-7-(3-methylphenyl)-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C23H24N2O2
|
2
|
| 1 |
IC50 = 13000 nM
|
|
|
| 2 |
IC50 = 15000 nM
|
|
|
|
CP0858211
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-4,5-dihydrobenzo[f][1,4]oxazepin-3(2H)-one
Show/Hide
|
C24H20N2O3S
|
2
|
| 1 |
IC50 = 13000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0865567
|
7-(Benzo[b]thiophen-3-yl)-9-ethoxy-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C25H24N2O2S
|
2
|
| 1 |
IC50 = 14000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0875366
|
9-Methoxy-7-phenyl-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C22H22N2O2
|
2
|
| 1 |
IC50 = 15000 nM
|
|
|
| 2 |
IC50 > 30000 nM
|
|
|
|
CP0444658
|
9-methoxy-7-(4-methylphenyl)-4-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzoxazepine
Show/Hide
|
C23H24N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0694104
|
7-(Benzo[b]thiophen-3-yl)-4-(4-chlorobenzyl)-9-methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C25H22ClNO2S
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
IC50 = 30000 nM
|
|
|
|
CP0709124
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(4-methylbenzyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C26H25NO2S
|
2
|
| 1 |
IC50 > 30000 nM
|
|
|
| 2 |
IC50 = 30000 nM
|
|
|
|
CP0846793
|
7-(Benzo[b]thiophen-3-yl)-9-isopropoxy-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C26H26N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0858210
|
7-(Benzo[b]thiophen-3-yl)-9-methoxy-4-(pyridin-3-ylmethyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one
Show/Hide
|
C24H20N2O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0865019
|
9-Methoxy-4-(pyridin-3-ylmethyl)-7-(o-tolyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C23H24N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0908414
|
9-Methoxy-4-(pyridin-3-ylmethyl)-7-(thiophen-3-yl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0651928
|
7-(Benzo[b]thiophen-3-yl)-4-(3-chlorobenzyl)-9-methoxy-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
Show/Hide
|
C25H22ClNO2S
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
