General Information of the Compound
Compound ID
CP0846793
Compound Name
7-(Benzo[b]thiophen-3-yl)-9-isopropoxy-4-(pyridin-3-ylmethyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine
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Structure
Formula
C26H26N2O2S
Molecular Weight
430.573
Canonical SMILES
CC(C)Oc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1)C2
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InChI
InChI=1S/C26H26N2O2S/c1-18(2)30-24-13-20(23-17-31-25-8-4-3-7-22(23)25)12-21-16-28(10-11-29-26(21)24)15-19-6-5-9-27-14-19/h3-9,12-14,17-18H,10-11,15-16H2,1-2H3
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InChIKey
HQJHTRNXNSGGOK-UHFFFAOYSA-N
Physicochemical Property
logP
6.1451
Rotatable Bonds
5
Heavy Atom Count
31
Polar Areas
34.59
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 122180287
ChEMBL ID
CHEMBL3586351
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00948, Prostaglandin E2 receptor EP2 subtype
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000516 ECV-304 Homo sapiens (Human)  1
1
IC50 > 30000 nM
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