Brief Information of the Cell Line and Protein
Cell Line ID: CL000384 , 3T3-L1
Synonyms
3T3 L1
3T3L1
3T3-L1 ad
NIH-3T3-L1
NIH3T3-L1
Category Spontaneously immortalized cell line
Organism
Mus musculus (Mouse)
Cellosaurus ID
CVCL_0123
Protein ID: PT01109 , 11-beta-hydroxysteroid dehydrogenase 1
Gene Name HSD11B1
Organism Mus musculus, Mouse
Protein Classification Enzyme
Uniprot ID P50172
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000384  Protein ID: PT01109
 
Compound ID Compound Name Compound Formula
CP0105606
3-[1-(4-chlorophenyl)cyclopropyl]-8-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridine
   Show/Hide
C18H16ClN3
 1
1
IC50 = 293 nM
   TI
   LI
   LO
   TS
CP0323516
1-[(2-chlorophenyl)methoxy]-7-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
   Show/Hide
C17H10ClFN2O2
 1
1
IC50 = 2162 nM
   TI
   LI
   LO
   TS
CP0169237
1-[(2-chlorophenyl)methylsulfanyl]-7-fluoro-3-oxo-2H-isoquinoline-4-carbonitrile
   Show/Hide
C17H10ClFN2OS
 1
1
IC50 = 2254 nM
   TI
   LI
   LO
   TS
CP0132715
2-[(2-chlorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
   Show/Hide
C18H12ClN3OS
 1
1
IC50 = 2854 nM
   TI
   LI
   LO
   TS
CP0335646
1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
   Show/Hide
C17H15ClN2OS
 1
1
IC50 = 3508 nM
   TI
   LI
   LO
   TS
CP0335642
8-[(2-cyanopyridin-3-yl)methylsulfanyl]-6-oxo-1,3,4,7-tetrahydropyrano[3,4-c]pyridine-5-carbonitrile
   Show/Hide
C16H12N4O2S
 1
1
IC50 = 3966 nM
   TI
   LI
   LO
   TS