Brief Information of the Compound and Protein
Compound Name
8-[(2-cyanopyridin-3-yl)methylsulfanyl]-6-oxo-1,3,4,7-tetrahydropyrano[3,4-c]pyridine-5-carbonitrile
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PubChem ID
CID: 53470409
SID: 135635451
Canonical SMILES
O=c1[nH]c(SCc2cccnc2C#N)c2COCCc2c1C#N
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Compound Formula C16H12N4O2S
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000384 3T3-L1 Mus musculus (Mouse)  1
1
IC50 = 3966 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 105 nM