Brief Information of the Compound and Protein
Compound Name
2-[(2-chlorophenyl)methylsulfanyl]-6-oxo-4-phenyl-1H-pyrimidine-5-carbonitrile
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PubChem ID
CID: 135416151
SID: 51075996
Canonical SMILES
Clc1ccccc1CSc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1
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Compound Formula C18H12ClN3OS
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000384 3T3-L1 Mus musculus (Mouse)  1
1
IC50 = 2854 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 58 nM