Brief Information of the Compound and Protein
Compound Name
1-[(2-chlorophenyl)methylsulfanyl]-3-oxo-5,6,7,8-tetrahydro-2H-isoquinoline-4-carbonitrile
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PubChem ID
CID: 24884555
SID: 51075997
Canonical SMILES
Clc1ccccc1CSc1[nH]c(=O)c(C#N)c2CCCCc12
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Compound Formula C17H15ClN2OS
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000384 3T3-L1 Mus musculus (Mouse)  1
1
IC50 = 3508 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM