Brief Information of the Cell Line and Protein
Cell Line ID: CL000275 , AGS
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0139
Protein ID: PT02791 , Hypoxia-inducible factor 1-alpha
Gene Name HIF1A
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID Q16665
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000275  Protein ID: PT02791
 
Compound ID Compound Name Compound Formula
CP0378883
3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzoic acid
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C25H27NO4
 1
1
IC50 = 350 nM
   TI
   LI
   LO
   TS
CP0499642
3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzoic acid methyl ester
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C26H29NO4
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0490586
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid
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C24H26N2O4
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0449106
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinamide
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C24H27N3O3
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0457924
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-nicotinamide
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C31H34N4O3
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0393031
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinamide
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C24H27N3O3
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0016093
(5-(1-benzyl-1H-indazol-3-yl)furan-2-yl)methanol
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C19H16N2O2
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0454169
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-isonicotinic acid methyl ester
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C25H28N2O4
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0454171
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid methyl ester
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C25H28N2O4
 1
1
IC50 = 5000 nM
   TI
   LI
   LO
   TS
CP0434361
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(2-pyridin-4-yl-ethyl)-isonicotinamide
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C31H34N4O3
 1
1
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0440841
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-nicotinamide
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C30H35N5O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0442349
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(3-imidazol-1-yl-propyl)-isonicotinamide
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C30H35N5O3
 1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0399590
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-(4-chloro-phenyl)-isonicotinamide
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C30H30ClN3O3
 1
1
IC50 = 18600 nM
   TI
   LI
   LO
   TS
CP0454170
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-nicotinic acid
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C24H26N2O4
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0454275
5-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-nicotinamide
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C29H31N3O4
 1
1
IC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0464172
2-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-N-furan-2-ylmethyl-isonicotinamide
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C29H31N3O4
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS