Brief Information of the Compound and Protein
Compound Name
3-[2-(4-adamantan-1-yl-phenoxy)-acetylamino]-benzoic acid methyl ester
    Show/Hide
PubChem ID
CID: 3906683
SID: 49757737
Canonical SMILES
COC(=O)c1cccc(NC(=O)COc2ccc(cc2)C23CC4CC(CC(C4)C2)C3)c1
    Show/Hide
Compound Formula C26H29NO4
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000275 AGS Homo sapiens (Human)  1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CL000067 HCT 116 Homo sapiens (Human)  1
1
IC50 = 5030 nM
   TI
   LI
   LO
   TS
CL000273 Hep 3B2.1-7 Homo sapiens (Human)  1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS