| Compound ID |
Compound Name |
Compound Formula |
|
CP0397395
|
dimethyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2,6-dicarboxylate
Show/Hide
|
C29H28O9
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
|
CP0453495
|
(1R,2R,3S,3aR,8bS)-6-chloro-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Show/Hide
|
C28H28ClNO6
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
|
| 2 |
EC50 = 15 nM
|
|
|
|
CP0118102
|
methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C34H38O13
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
EC50 = 7 nM
|
|
|
|
CP0453494
|
(1R,2R,3S,3aR,8bS)-6-cyano-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Show/Hide
|
C29H28N2O6
|
2
|
| 1 |
EC50 = 0.8 nM
|
|
|
| 2 |
EC50 = 35 nM
|
|
|
|
CP0462863
|
methyl (1R,2R,3S,3aR,8bS)-6-cyano-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H25NO7
|
2
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
EC50 = 15 nM
|
|
|
|
CP0423624
|
methyl (1R,2R,3S,3aR,8bS)-6-acetyl-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C29H28O8
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
EC50 = 30 nM
|
|
|
|
CP0462855
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,3R,6S)-6-(2-hydroxyethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C34H38O12
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
EC50 = 5 nM
|
|
|
|
CP0397393
|
(1R,2R,3S,3aR,8bS)-3a-(4-cyanophenyl)-1,8b-dihydroxy-6,8-dimethoxy-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Show/Hide
|
C29H28N2O6
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 = 40 nM
|
|
|
|
CP0423642
|
methyl (1R,2R,3S,3aR,8bS)-3a-(4-cyanophenyl)-1,8b-dihydroxy-6,8-dimethoxy-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H25NO7
|
2
|
| 1 |
EC50 = 2 nM
|
|
|
| 2 |
EC50 = 17 nM
|
|
|
|
CP0397396
|
(1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1S)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Show/Hide
|
C35H41NO12
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 19 nM
|
|
|
|
CP0423625
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,6S)-6-(hydroxymethyl)-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C32H34O11
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 40 nM
|
|
|
|
CP0423630
|
methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,6R)-6-[(1R)-1,2-dihydroxyethyl]-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H36O12
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 14 nM
|
|
|
|
CP0423641
|
(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,6S)-6-(hydroxymethyl)-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
Show/Hide
|
C33H37NO10
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 23 nM
|
|
|
|
CP0462854
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,3R,6S)-6-(hydroxymethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H36O12
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 60 nM
|
|
|
|
CP0397384
|
methyl (1R,2R,3S,3aR,8bS)-6-chloro-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C27H25ClO7
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
EC50 = 70 nM
|
|
|
|
CP0453491
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methylphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H28O7
|
2
|
| 1 |
EC50 = 5 nM
|
|
|
| 2 |
EC50 > 100 nM
|
|
|
|
CP0304472
|
AGLAFOLIN
Show/Hide
|
C28H28O8
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
EC50 = 90 nM
|
|
|
|
CP0423643
|
methyl (1R,2R,3S,3aR,8bS)-1,6,8b-trihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C27H26O8
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
EC50 = 200 nM
|
|
|
|
CP0493559
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-6-(methylamino)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H29NO7
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
EC50 = 700 nM
|
|
|
|
CP0397385
|
methyl (1R,2R,3S,3aR,8bS)-6-carbamoyl-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H27NO8
|
2
|
| 1 |
EC50 = 29 nM
|
|
|
| 2 |
EC50 = 450 nM
|
|
|
|
CP0397394
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2R,3R,6S)-6-(hydroxymethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H36O12
|
2
|
| 1 |
EC50 = 35 nM
|
|
|
| 2 |
EC50 = 240 nM
|
|
|
|
CP0423628
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,3S,6S)-6-(2-hydroxyethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C34H38O12
|
2
|
| 1 |
EC50 = 35 nM
|
|
|
| 2 |
EC50 = 275 nM
|
|
|
|
CP0462853
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-6-(methylcarbamoyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C29H29NO8
|
2
|
| 1 |
EC50 = 35 nM
|
|
|
| 2 |
EC50 > 2000 nM
|
|
|
|
CP0397388
|
methyl (1R,2R,3S,3aR,8bS)-6-amino-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C27H27NO7
|
2
|
| 1 |
EC50 = 40 nM
|
|
|
| 2 |
EC50 > 2000 nM
|
|
|
|
CP0453490
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[(2S,6S)-6-(hydroxymethyl)oxan-2-yl]oxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H36O10
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
EC50 = 2000 nM
|
|
|
|
CP0397392
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[(2S,6S)-6-(hydroxymethyl)morpholin-2-yl]oxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C32H35NO10
|
2
|
| 1 |
EC50 = 80 nM
|
|
|
| 2 |
EC50 = 3500 nM
|
|
|
|
CP0397383
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2R,3S,6S)-6-(2-hydroxyethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C34H38O12
|
2
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
EC50 > 2000 nM
|
|
|
|
CP0462852
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,3S,6S)-6-(hydroxymethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H36O12
|
2
|
| 1 |
EC50 = 170 nM
|
|
|
| 2 |
EC50 > 2500 nM
|
|
|
|
CP0423640
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2R,3R,6S)-6-(2-hydroxyethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C34H38O12
|
2
|
| 1 |
EC50 > 200 nM
|
|
|
| 2 |
EC50 > 3500 nM
|
|
|
|
CP0397390
|
(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-2-methoxycarbonyl-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-6-carboxylic acid
Show/Hide
|
C28H26O9
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
EC50 > 5000 nM
|
|
|
|
CP0397381
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C27H26O7
|
2
|
| 1 |
EC50 > 2000 nM
|
|
|
| 2 |
EC50 > 5000 nM
|
|
|
|
CP0397382
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2R,3S,6S)-6-(hydroxymethyl)-3-methoxy-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H36O12
|
2
|
| 1 |
EC50 > 2000 nM
|
|
|
| 2 |
EC50 > 5000 nM
|
|
|
|
CP0397387
|
methyl (1R,2R,3S,3aR,8bS)-6-(dimethylamino)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C29H31NO7
|
2
|
| 1 |
EC50 > 2000 nM
|
|
|
| 2 |
EC50 > 5000 nM
|
|
|
|
CP0423636
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-(methanesulfonamido)-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H29NO9S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0423637
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-6-methyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C28H28O7
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0423639
|
methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[(2S,6S)-6-(hydroxymethyl)-4-methylmorpholin-2-yl]oxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C33H37NO10
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0453523
|
methyl (1R,2R,3S,3aR,8bS)-6-(dimethylcarbamoyl)-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Show/Hide
|
C30H31NO8
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
