Brief Information of the Compound and Protein
Compound Name
(1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6-[[(2S,6S)-6-(hydroxymethyl)-1,4-dioxan-2-yl]oxy]-8-methoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
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PubChem ID
CID: 71455192
SID: 163456893
Canonical SMILES
COc1ccc(cc1)[C@@]12Oc3cc(O[C@H]4COC[C@H](CO)O4)cc(OC)c3[C@]1(O)[C@H](O)[C@@H]([C@H]2c1ccccc1)C(=O)N(C)C
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Compound Formula C33H37NO10
Compound Structure
Protein Name
Eukaryotic initiation factor 4A-I
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P60842
Gene Name
EIF4A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000111 MDA-MB-231 Homo sapiens (Human)  2
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
2
EC50 = 23 nM
   TI
   LI
   LO
   TS