Brief Information of the Compound and Protein
Compound Name
methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,6R)-6-[(1R)-1,2-dihydroxyethyl]-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
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PubChem ID
CID: 71456989
SID: 163455051
Canonical SMILES
COC(=O)[C@H]1[C@@H](O)[C@@]2(O)c3c(O[C@]2([C@@H]1c1ccccc1)c1ccc(OC)cc1)cc(O[C@H]1COC[C@@H](O1)[C@H](O)CO)cc3OC
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Compound Formula C33H36O12
Compound Structure
Protein Name
Eukaryotic initiation factor 4A-I
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P60842
Gene Name
EIF4A1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000111 MDA-MB-231 Homo sapiens (Human)  2
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
2
EC50 = 14 nM
   TI
   LI
   LO
   TS