| Compound ID |
Compound Name |
Compound Formula |
|
CP0041607
|
(AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C10H13N5O4
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0496581
|
(5R,6R)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-6-methoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C11H16IN5O5
|
1
|
| 1 |
EC50 = 3.17 nM
|
|
|
|
CP0375508
|
(5R,6R)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-6-methoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C11H16BrN5O5
|
1
|
| 1 |
EC50 = 3.27 nM
|
|
|
|
CP0520338
|
(5S,6S)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-6-methoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C11H16IN5O5
|
1
|
| 1 |
EC50 = 5.15 nM
|
|
|
|
CP0528779
|
(5R,6R)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-6-ethoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C12H18BrN5O5
|
1
|
| 1 |
EC50 = 6.75 nM
|
|
|
|
CP0503499
|
(5S,6S)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-6-ethoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C12H18BrN5O5
|
1
|
| 1 |
EC50 = 23.7 nM
|
|
|
|
CP0096367
|
1-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C25H45N3O8SSi2
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0141639
|
1-[(6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2lambda6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione
Show/Hide
|
C24H43N3O8SSi2
|
2
|
| 1 |
EC50 = 50 nM
|
|
|
| 2 |
EC50 = 60 nM
|
|
|
|
CP0850206
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-iodo-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C25H44IN3O8SSi2
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0082036
|
1-[(5R,6R,8R,9R)-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-iodo-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C24H42IN3O8SSi2
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0529870
|
(5S,6S)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-6-methoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C11H16BrN5O5
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0889438
|
1-[4-Amino-3-bromo-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C24H42BrN3O8SSi2
|
1
|
| 1 |
EC50 = 850 nM
|
|
|
|
CP0397344
|
(5R,6R)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-5-methyl-6-octoxy-1,3-diazinane-2,4-dione
Show/Hide
|
C18H30BrN5O5
|
1
|
| 1 |
EC50 = 865 nM
|
|
|
|
CP0891921
|
3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-8-(3,5-dimethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-3-yl]-acrylic acid methyl ester
Show/Hide
|
C29H49N3O10SSi2
|
1
|
| 1 |
EC50 = 980 nM
|
|
|
|
CP0505164
|
6-azido-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-chloro-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C10H13ClN8O4
|
1
|
| 1 |
EC50 = 1490 nM
|
|
|
|
CP0712238
|
{3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid
Show/Hide
|
C24H44N2O8Si2
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0930736
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C26H47N3O8SSi2
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0897698
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-3-phenyl-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C30H47N3O8SSi2
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0874546
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-(3-hydroxy-propenyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C28H49N3O9SSi2
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0860032
|
3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-8-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-3-yl]-acrylic acid methyl ester
Show/Hide
|
C28H47N3O10SSi2
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0878059
|
3-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-8-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-3-yl]-acrylic acid ethyl ester
Show/Hide
|
C29H49N3O10SSi2
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0927012
|
{3-[3-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid benzyl ester
Show/Hide
|
C25H36N2O8Si
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
|
CP0874413
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-3-vinyl-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C26H45N3O8SSi2
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
|
CP0149785
|
2-[3-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-hydroxyoxolan-2-yl]-5-methyl-2,6-dioxopyrimidin-1-yl]acetic acid
Show/Hide
|
C24H44N2O8Si2
|
1
|
| 1 |
EC50 = 4500 nM
|
|
|
|
CP0221683
|
2-[3-[3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-methyl-2,6-dioxopyrimidin-1-yl]acetic acid
Show/Hide
|
C24H44N2O7Si2
|
1
|
| 1 |
EC50 = 4500 nM
|
|
|
|
CP0850157
|
{3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid
Show/Hide
|
C24H44N2O7Si2
|
1
|
| 1 |
EC50 = 5000 nM
|
|
|
|
CP0529922
|
(5R,6R)-1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-bromo-5-methyl-6-propan-2-yloxy-1,3-diazinane-2,4-dione
Show/Hide
|
C13H20BrN5O5
|
1
|
| 1 |
EC50 = 5720 nM
|
|
|
|
CP0496726
|
(6R)-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-chloro-6-methoxy-5-methyl-1,3-diazinane-2,4-dione
Show/Hide
|
C11H16ClN5O5
|
1
|
| 1 |
EC50 = 5790 nM
|
|
|
|
CP0408758
|
benzyl 2-[3-[(3R,4S,5R)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]-5-methyl-2,6-dioxopyrimidin-1-yl]acetate
Show/Hide
|
C25H36N2O8Si
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0881031
|
{3-[3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid benzyl ester
Show/Hide
|
C31H50N2O8Si2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0914588
|
{3-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid benzyl ester
Show/Hide
|
C37H64N2O8Si3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0914593
|
{3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid benzyl ester
Show/Hide
|
C31H50N2O7Si2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0881070
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-chloro-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C24H42ClN3O8SSi2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0847076
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-hydroxymethyl-2,2-dioxo-3-vinyl-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C20H31N3O8SSi
|
1
|
| 1 |
EC50 = 15000 nM
|
|
|
|
CP0878569
|
{3-[3-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid
Show/Hide
|
C18H30N2O8Si
|
1
|
| 1 |
EC50 = 20000 nM
|
|
|
|
CP0919814
|
{3-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid
Show/Hide
|
C30H58N2O8Si3
|
1
|
| 1 |
EC50 = 32000 nM
|
|
|
|
CP0874528
|
{3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-3-hydroxy-tetrahydro-furan-2-yl]-5-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl}-acetic acid benzyl ester
Show/Hide
|
C31H50N2O8Si2
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0859721
|
1-[4-Allylamino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C28H49N3O8SSi2
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0885511
|
1-[3-Allyl-4-amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C28H49N3O8SSi2
|
1
|
| 1 |
EC50 > 50000 nM
|
|
|
|
CP0878581
|
1-[9-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-methyl-4-methylamino-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C27H49N3O8SSi2
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0403716
|
benzyl 2-[3-[3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-methyl-2,6-dioxopyrimidin-1-yl]acetate
Show/Hide
|
C31H50N2O7Si2
|
1
|
| 1 |
EC50 > 2000 nM
|
|
|
|
CP0777067
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-3-(3-hydroxy-propenyl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-5-methyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C27H47N3O9SSi2
|
1
|
| 1 |
EC50 > 2000 nM
|
|
|
|
CP0863181
|
2-[9-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-4-(carbamoylmethyl-amino)-8-(3,5-dimethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-3-yl]-acetamide
Show/Hide
|
C29H51N5O10SSi2
|
1
|
| 1 |
EC50 > 2000 nM
|
|
|
|
CP0870939
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-3-thiophen-3-yl-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C29H47N3O8S2Si2
|
1
|
| 1 |
EC50 > 2000 nM
|
|
|
|
CP0870947
|
1-[4-Amino-9-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-2,2-dioxo-3-prop-1-ynyl-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-8-yl]-3,5-dimethyl-1H-pyrimidine-2,4-dione
Show/Hide
|
C28H47N3O8SSi2
|
1
|
| 1 |
EC50 > 2000 nM
|
|
|
