Brief Information of the Compound and Protein
Compound Name
2-[9-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-dimethyl-silanyloxymethyl)-4-(carbamoylmethyl-amino)-8-(3,5-dimethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,2-dioxo-1,7-dioxa-2lambda*6*-thia-spiro[4.4]non-3-en-3-yl]-acetamide
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PubChem ID
CID: 10897866
SID: 15945318
Canonical SMILES
Cc1cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C(CC(N)=O)=C3NCC(N)=O)[C@H]2O[Si](C)(C)C(C)(C)C)c(=O)n(C)c1=O
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Compound Formula C29H51N5O10SSi2
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM Homo sapiens (Human)  1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS
CL000247 MT-4 Homo sapiens (Human)  1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS