Brief Information of the Compound and Protein
Compound Name
2-[3-[3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-methyl-2,6-dioxopyrimidin-1-yl]acetic acid
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PubChem ID
CID: 44334945
Canonical SMILES
Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)CC2O[Si](C)(C)C(C)(C)C)c(=O)n(CC(O)=O)c1=O
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Compound Formula C24H44N2O7Si2
Compound Structure
Protein Name
Reverse transcriptase/RNaseH
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q72547
Gene Name
POL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM Homo sapiens (Human)  1
1
EC50 = 4500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1100 nM
2 IC50 = 5700 nM
3 IC50 = 33800 nM
4 IC50 = 47400 nM