| Compound ID |
Compound Name |
Compound Formula |
|
CP0507826
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzamido)phenyl)propanoic acid
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|
C33H27Cl2N3O7
|
1
|
| 1 |
IC50 = 100 nM
|
|
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CP0545375
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(thiazol-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C24H21Cl2N3O7S
|
1
|
| 1 |
IC50 = 200 nM
|
|
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CP0489473
|
(S)-2-((4R,5R)-5-(cyclopropylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C24H24Cl2N2O7
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
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CP0526903
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(3,5-dichloropyridin-4-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C26H21Cl4N3O7
|
1
|
| 1 |
IC50 = 400 nM
|
|
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CP0507560
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(2,6-difluorophenylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C27H22Cl2F2N2O7
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
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CP0507835
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C33H28Cl2N2O7
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
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CP0493063
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(2-methoxyphenylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C28H26Cl2N2O8
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
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CP0507836
|
(S)-2-((4R,5R)-5-(2-(1H-indol-3-yl)ethylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C31H29Cl2N3O7
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
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CP0513602
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(2-fluorophenylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C27H23Cl2FN2O7
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
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CP0514868
|
(S)-2-((4R,5R)-5-(benzo[d]thiazol-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C28H23Cl2N3O7S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
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CP0507837
|
(S)-2-((4R,5R)-5-(2-chlorophenylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C27H23Cl3N2O7
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
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CP0507840
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(2,6-dichlorophenylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C27H22Cl4N2O7
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
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CP0534670
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(thiophen-2-ylmethylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C26H24Cl2N2O7S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
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CP0526902
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(2-(trifluoromethyl)phenylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C28H23Cl2F3N2O7
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0497171
|
(S)-2-((4R,5R)-5-(1-benzyl-3-tert-butyl-1H-pyrazol-5-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C35H36Cl2N4O7
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0377165
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(isopentylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C26H30Cl2N2O7
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
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CP0417118
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(methylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C22H22Cl2N2O7
|
1
|
| 1 |
IC50 = 1200 nM
|
|
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CP0501635
|
(S)-2-((4R,5R)-5-(tert-butylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C25H28Cl2N2O7
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
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CP0507653
|
(S)-2-((4R,5R)-5-(cyclohexylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C27H30Cl2N2O7
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
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CP0470867
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(5-methyl-1,3,4-thiadiazol-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C24H22Cl2N4O7S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0493062
|
(S)-2-((4R,5R)-5-(butylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C25H28Cl2N2O7
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0501634
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(dimethylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C23H24Cl2N2O7
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0507839
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(phenylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C27H24Cl2N2O7
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0513600
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(ethylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C23H24Cl2N2O7
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
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CP0507841
|
(S)-2-((4R,5R)-5-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C35H36Cl2N4O7
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
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CP0417116
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(isonicotinamido)phenyl)propanoic acid
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|
C32H28N4O7
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
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CP0477607
|
(S)-2-((4R,5R)-5-(4-chlorophenylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C27H23Cl3N2O7
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
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CP0507654
|
(S)-2-((4R,5R)-5-(benzo[d][1,3]dioxol-5-ylmethylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichlorobenzyloxy)phenyl)propanoic acid
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|
C29H26Cl2N2O9
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
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CP0522745
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(morpholine-4-carbonyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C25H26Cl2N2O8
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
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CP0501633
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(heptylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C28H34Cl2N2O7
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
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CP0507825
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-dichloroisonicotinamido)phenyl)propanoic acid
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|
C32H26Cl2N4O7
|
1
|
| 1 |
IC50 = 6300 nM
|
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CP0534669
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2-methoxybenzamido)phenyl)propanoic acid
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|
C34H31N3O8
|
1
|
| 1 |
IC50 = 6300 nM
|
|
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CP0513601
|
(S)-3-(4-(2,6-dichlorobenzyloxy)phenyl)-2-((4R,5R)-5-(isopropylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C24H26Cl2N2O7
|
1
|
| 1 |
IC50 = 6600 nM
|
|
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CP0417117
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2,6-difluorobenzyloxy)phenyl)propanoic acid
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|
C33H28F2N2O7
|
1
|
| 1 |
IC50 = 7900 nM
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CP0487887
|
(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(picolinamido)phenyl)propanoic acid
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|
C32H28N4O7
|
1
|
| 1 |
IC50 = 8300 nM
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CP0398611
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(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(2-chlorobenzyloxy)phenyl)propanoic acid
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|
C33H29ClN2O7
|
1
|
| 1 |
IC50 = 8700 nM
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CP0507833
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(S)-3-(4-benzamidophenyl)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)propanoic acid
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|
C33H29N3O7
|
1
|
| 1 |
IC50 = 9000 nM
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CP0507832
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(S)-2-((4R,5R)-5-(biphenyl-2-ylcarbamoyl)-1,3-dioxolane-4-carboxamido)-3-(4-(nicotinamido)phenyl)propanoic acid
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|
C32H28N4O7
|
1
|
| 1 |
IC50 = 9500 nM
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