| Compound ID |
Compound Name |
Compound Formula |
|
CP0494761
|
4-(4-chlorophenyl)-3-fluoro-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C26H26ClFN2O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0563632
|
4-(4-chlorophenyl)-2-fluoro-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C26H26ClFN2O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0257485
|
4-(4-chlorophenyl)-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C26H27ClN2O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0487089
|
N-[2-[2-bromo-4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]-4-(4-chlorophenyl)benzamide
Show/Hide
|
C26H26BrClN2O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0494759
|
4-(4-chlorophenyl)-N-[2-[4-[(2-hydroxyethylamino)methyl]phenyl]ethyl]benzamide
Show/Hide
|
C24H25ClN2O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0530326
|
4-(4-chlorophenyl)-N-[2-[4-(piperidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C27H29ClN2O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0198887
|
N-[2-[4-[(4-acetamidopiperidin-1-yl)methyl]phenyl]ethyl]-4-(4-fluorophenyl)benzamide
Show/Hide
|
C29H32FN3O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0563633
|
4-(4-fluorophenyl)-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C26H27FN2O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0067175
|
[(2S)-1-[2-[4-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]-2-methylphenoxy]ethyl]pyrrolidin-2-yl]methanol
Show/Hide
|
C27H27ClN2O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0146660
|
5-(4-chlorophenyl)-3-fluoro-2-[2-[4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]ethynyl]pyridine
Show/Hide
|
C27H26ClFN2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0184990
|
5-(4-chlorophenyl)-2-[2-[4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl]ethynyl]pyridine
Show/Hide
|
C27H27ClN2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0272481
|
4-(4-fluorophenyl)-N-[2-[4-[[4-(2-oxopropylamino)piperidin-1-yl]methyl]phenyl]ethyl]benzamide
Show/Hide
|
C30H34FN3O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0401586
|
5-(4-chlorophenyl)-2-[2-[3-chloro-4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridine
Show/Hide
|
C25H22Cl2N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0448962
|
4-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]-N-(2-pyrrolidin-1-ylethyl)aniline
Show/Hide
|
C25H24ClN3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0192989
|
N-[2-[4-[(4-acetylpiperazin-1-yl)methyl]phenyl]ethyl]-4-(4-chlorophenyl)benzamide
Show/Hide
|
C28H30ClN3O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0456122
|
1-[2-[4-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]phenoxy]ethyl]-4-(trifluoromethyl)piperidin-4-ol
Show/Hide
|
C27H24ClF3N2O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0487088
|
4-(4-chlorophenyl)-N-[2-[3-methoxy-4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C27H29ClN2O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0530328
|
5-(4-bromophenyl)-2-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridine
Show/Hide
|
C25H23BrN2O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0530329
|
5-(4-chlorophenyl)-2-[2-[6-(2-pyrrolidin-1-ylethoxy)pyridin-3-yl]ethynyl]pyridine
Show/Hide
|
C24H22ClN3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0067174
|
5-(4-chlorophenyl)-2-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridine
Show/Hide
|
C25H23ClN2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0484529
|
1-[2-[4-[(dimethylamino)methyl]phenyl]ethyl]-4-phenylmethoxypyridin-2-one
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0146659
|
1-[2-[4-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]phenoxy]ethyl]piperidine-4-carboxamide
Show/Hide
|
C27H26ClN3O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0257487
|
[(2R)-1-[2-[4-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]phenoxy]ethyl]pyrrolidin-2-yl]methanol
Show/Hide
|
C26H25ClN2O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0487090
|
4-(4-chlorophenyl)-N-methyl-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C27H29ClN2O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0563631
|
4-(4-chlorophenyl)-N-[2-[4-[[[2-(dimethylamino)-2-oxoethyl]-ethylamino]methyl]phenyl]ethyl]benzamide
Show/Hide
|
C28H32ClN3O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0498898
|
US8933079, 5.2
Show/Hide
|
C23H25N3O3
|
2
|
| 1 |
IC50 = 8.7 nM
|
|
|
| 2 |
IC50 = 9 nM
|
|
|
|
CP0428508
|
1-[2-[4-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]phenoxy]ethyl]-4-methylpiperazine
Show/Hide
|
C26H26ClN3O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0494764
|
2-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]-5-(2-pyrrolidin-1-ylethoxy)pyridine
Show/Hide
|
C24H22ClN3O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0534572
|
4-(2,4-dichlorophenyl)-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C26H26Cl2N2O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0445500
|
2-[2-[4-[(dimethylamino)methyl]phenyl]-2-oxoethyl]-5-phenylmethoxypyridazin-3-one
Show/Hide
|
C22H23N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0450241
|
US8933079, 5.7
Show/Hide
|
C24H25N3O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0450242
|
US8933079, 5.14
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0550532
|
US8933079, 5.6
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0272482
|
N-[2-[4-[(4-acetamidopiperidin-1-yl)methyl]phenyl]ethyl]-4-(4-fluorophenyl)-N-methylbenzamide
Show/Hide
|
C30H34FN3O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0534574
|
5-(4-chlorophenyl)-2-[2-[4-(3-pyrrolidin-1-ylpropyl)phenyl]ethynyl]pyridine
Show/Hide
|
C26H25ClN2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0491483
|
US8933079, 5.5
Show/Hide
|
C25H27N3O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0531822
|
US8933079, 5.3
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0532682
|
US8933079, 1.7
Show/Hide
|
C26H28N2O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0547626
|
US8933079, 1.9
Show/Hide
|
C27H30N2O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0534575
|
3-(4-chlorophenyl)-6-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridazine
Show/Hide
|
C24H22ClN3O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0547630
|
US8933079, 5.4
Show/Hide
|
C25H27N3O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0556059
|
US8933079, 4.16
Show/Hide
|
C26H28BrN3O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0443167
|
1-[2-[4-[(dimethylamino)methyl]phenyl]-2-oxoethyl]-4-phenylmethoxypyridin-2-one
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0516248
|
US8933079, 5.11
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0518273
|
US8933079, 5.13
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0531645
|
US8933079, 5.12
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0531821
|
US8933079, 4.5
Show/Hide
|
C26H28BrN3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0565220
|
US8933079, 4.3
Show/Hide
|
C27H30BrN3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0506975
|
US8933079, 4.7
Show/Hide
|
C27H30BrN3O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0553815
|
US8933079, 4.19
Show/Hide
|
C25H27BrN4O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0553816
|
US8933079, 5.1
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0494762
|
N-[4-[2-(diethylamino)ethoxy]phenyl]-4-(4-methoxyphenyl)-N-methylbenzamide
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0443109
|
US8933079, 5.8
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0448519
|
US8933079, 8.3
Show/Hide
|
C22H23BrN4O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0506973
|
US8933079, 4.2
Show/Hide
|
C26H28BrN3O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0518276
|
US8933079, 7.5
Show/Hide
|
C25H27ClN4O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0536304
|
US8933079, 1.18
Show/Hide
|
C28H30N2O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0494765
|
2-(4-chlorophenyl)-5-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyrazine
Show/Hide
|
C24H22ClN3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0450239
|
US8933079, 1.8
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0498899
|
US8933079, 4.1
Show/Hide
|
C23H24BrN3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0450249
|
US8933079, 8.8
Show/Hide
|
C22H23BrN4O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0483273
|
US8933079, 4.8
Show/Hide
|
C25H26BrN3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0443110
|
US8933079, 8.9
Show/Hide
|
C25H27BrN4O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0450248
|
US8933079, 8.5
Show/Hide
|
C25H27BrN4O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0470189
|
US8933079, 4.21
Show/Hide
|
C23H23BrN4O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0506974
|
US8933079, 4.4
Show/Hide
|
C26H28BrN3O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0506976
|
US8933079, 4.15
Show/Hide
|
C24H26BrN3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0530388
|
US8933079, 7.7
Show/Hide
|
C22H23ClN4O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0556467
|
US8933079, 4.17
Show/Hide
|
C25H28BrN3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0424135
|
US8933079, 1.2
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0450225
|
US8933079, 1.3
Show/Hide
|
C27H30N2O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0450247
|
US8933079, 7.15
Show/Hide
|
C24H25ClN4O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0483275
|
US8933079, 8.2
Show/Hide
|
C23H23BrN4O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0506977
|
US8933079, 4.20
Show/Hide
|
C24H27BrN4O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0553814
|
US8933079, 4.18
Show/Hide
|
C24H26BrN3O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0456064
|
5-(4-methoxyphenyl)-2-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridine
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0563635
|
5-(4-chlorophenyl)-2-[2-[2-chloro-4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridine
Show/Hide
|
C25H22Cl2N2O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0483276
|
US8933079, 9.4
Show/Hide
|
C22H24N4O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0519509
|
US8933079, 10.1
Show/Hide
|
C24H28N4O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0531730
|
US8933079, 4.9
Show/Hide
|
C25H26BrN3O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0550527
|
US8933079, 8.7
Show/Hide
|
C26H29BrN4O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0565218
|
US8933079, 1.1
Show/Hide
|
C25H26N2O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0518556
|
US8933079, 1.12
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0519507
|
US8933079, 8.6
Show/Hide
|
C25H27BrN4O4
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0550528
|
US8933079, 8.11
Show/Hide
|
C25H27BrN4O4
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0071972
|
US8933079, 149
Show/Hide
|
C23H26N4O4
|
3
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
IC50 = 28 nM
|
|
|
| 3 |
Ki = 14 nM
|
|
|
|
CP0443166
|
5-[(5-bromopyridin-2-yl)methoxy]-2-[2-[4-[(dimethylamino)methyl]phenyl]-2-oxoethyl]pyridazin-3-one
Show/Hide
|
C21H21BrN4O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0553820
|
US8933079, 8.1
Show/Hide
|
C24H25BrN4O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0556078
|
US8933079, 10.2
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0532684
|
US8933079, 4.12
Show/Hide
|
C26H28BrN3O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0429016
|
US8933079, 7.16
Show/Hide
|
C22H23ClN4O3
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0443104
|
US8933079, 1.6
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0506980
|
US8933079, 9.5
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0565221
|
US8933079, 8.4
Show/Hide
|
C25H27BrN4O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0487584
|
5-[(5-chloropyridin-2-yl)methoxy]-2-[2-[4-[(dimethylamino)methyl]phenyl]-2-oxoethyl]pyridazin-3-one
Show/Hide
|
C21H21ClN4O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0500460
|
US8933079, 7.10
Show/Hide
|
C25H27ClN4O4
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0532686
|
US8933079, 8.10
Show/Hide
|
C21H21BrN4O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0532687
|
US8933079, 9.3
Show/Hide
|
C25H28N4O4
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0494763
|
5-(4-chlorophenyl)-2-[2-[4-(2-pyrrolidin-1-ylethyl)phenyl]ethynyl]pyridine
Show/Hide
|
C25H23ClN2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0470188
|
US8933079, 3.11
Show/Hide
|
C23H24ClN3O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0515449
|
US8933079, 3.8
Show/Hide
|
C25H26ClN3O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0530387
|
US8933079, 7.1
Show/Hide
|
C25H27ClN4O4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0532709
|
US8933079, 1.10
Show/Hide
|
C27H30N2O4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0550530
|
US8933079, 11.3
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0550533
|
US8933079, 7.8
Show/Hide
|
C26H29ClN4O4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0553807
|
US8933079, 3.6
Show/Hide
|
C26H28ClN3O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0554182
|
US8933079, 4.13
Show/Hide
|
C22H22BrN3O3
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0556466
|
US8933079, 1.17
Show/Hide
|
C27H30N2O4
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0506978
|
US8933079, 7.3
Show/Hide
|
C23H23ClN4O4
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0448520
|
4-[(5-bromopyridin-2-yl)methoxy]-1-[2-[4-[(dimethylamino)methyl]phenyl]-2-oxoethyl]pyridin-2-one
Show/Hide
|
C22H22BrN3O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0506979
|
US8933079, 7.6
Show/Hide
|
C21H21ClN4O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0448960
|
4-(3-chlorophenyl)-N-[2-[4-(pyrrolidin-1-ylmethyl)phenyl]ethyl]benzamide
Show/Hide
|
C26H27ClN2O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0504129
|
US8933079, 1.16
Show/Hide
|
C28H32N2O4
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0556465
|
US8933079, 1.13
Show/Hide
|
C27H30N2O4
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0491485
|
US8933079, 7.14
Show/Hide
|
C26H29ClN4O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0536303
|
US8933079, 1.11
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0547632
|
US8933079, 5.9
Show/Hide
|
C26H29N3O4
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0512619
|
US8933079, 1.15
Show/Hide
|
C27H30N2O4
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0518278
|
US8933079, 7.11
Show/Hide
|
C25H27ClN4O4
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0956773
|
US8933079, 3.15
Show/Hide
|
C24H24ClN3O4
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0443108
|
US8933079, 3.9
Show/Hide
|
C23H24ClN3O3
|
2
|
| 1 |
IC50 = 32 nM
|
|
|
| 2 |
IC50 = 33 nM
|
|
|
|
CP0553819
|
US8933079, 7.9
Show/Hide
|
C24H25ClN4O4
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0557042
|
N-[4-[2-(diethylamino)ethoxy]phenyl]-4-(4-methoxyphenyl)benzamide
Show/Hide
|
C26H30N2O3
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0519508
|
US8933079, 9.2
Show/Hide
|
C26H30N4O5
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0553808
|
US8933079, 3.13
Show/Hide
|
C26H28ClN3O4
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0565219
|
US8933079, 3.12
Show/Hide
|
C27H30ClN3O4
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0567335
|
N,N-diethyl-2-[4-[2-[5-(4-methoxyphenyl)pyridin-2-yl]ethynyl]phenoxy]ethanamine
Show/Hide
|
C26H28N2O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0491484
|
US8933079, 6.2
Show/Hide
|
C25H27FN4O3
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0547633
|
US8933079, 5.10
Show/Hide
|
C26H30N4O4
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0356812
|
4-(4-chlorophenyl)-N-[2-[4-[[ethylcarbamoyl(methyl)amino]methyl]phenyl]ethyl]-2-fluorobenzamide
Show/Hide
|
C26H27ClFN3O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0536306
|
US8933079, 3.7
Show/Hide
|
C26H28ClN3O4
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0550228
|
US8933079, 3.2
Show/Hide
|
C26H28ClN3O4
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0470187
|
US8933079, 3.10
Show/Hide
|
C22H22ClN3O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0531820
|
US8933079, 3.14
Show/Hide
|
C27H30ClN3O4
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0536305
|
US8933079, 3.4
Show/Hide
|
C25H26ClN3O4
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0547634
|
US8933079, 6.1
Show/Hide
|
C24H25FN4O3
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0491480
|
US8933079, 3.3
Show/Hide
|
C25H26ClN3O4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0506970
|
US8933079, 1.4
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0547754
|
4-[(5-chloropyridin-2-yl)methoxy]-1-[2-[4-[(dimethylamino)methyl]phenyl]-2-oxoethyl]pyridin-2-one
Show/Hide
|
C22H22ClN3O3
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0506971
|
US8933079, 1.5
Show/Hide
|
C27H31N3O3
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0518559
|
US8933079, 6.6
Show/Hide
|
C24H25FN4O4
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0515450
|
US8933079, 4.6
Show/Hide
|
C23H24BrN3O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0553817
|
US8933079, 6.5
Show/Hide
|
C22H23FN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0529069
|
US8933079, 1.14
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0550529
|
US8933079, 11.1
Show/Hide
|
C27H31N3O5
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0553809
|
US8933079, 4.10
Show/Hide
|
C27H31BrN4O3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0443111
|
US8933079, 11.4
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0528872
|
US8933079, 11.2
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0530386
|
US8933079, 6.4
Show/Hide
|
C25H27FN4O4
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0515107
|
US8933079, 6.3
Show/Hide
|
C22H23FN4O3
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0532683
|
US8933079, 4.11
Show/Hide
|
C25H26BrN3O4
|
1
|
| 1 |
IC50 = 59 nM
|
|
|
|
CP0506972
|
US8933079, 2.1
Show/Hide
|
C25H26FN3O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0558727
|
US8933079, 7.4
Show/Hide
|
C25H28ClN5O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0567334
|
N-[2-[4-(aminomethyl)phenyl]ethyl]-4-(4-chlorophenyl)benzamide
Show/Hide
|
C22H21ClN2O
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0530516
|
US8933079, 2.5
Show/Hide
|
C23H24FN3O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0519505
|
US8933079, 2.4
Show/Hide
|
C25H26FN3O4
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0483274
|
US8933079, 7.2
Show/Hide
|
C26H30ClN5O3
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0516247
|
US8933079, 4.14
Show/Hide
|
C26H29BrN4O3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0563634
|
3-[2-[5-(4-chlorophenyl)pyridin-2-yl]ethynyl]-6-(2-pyrrolidin-1-ylethoxy)pyridazine
Show/Hide
|
C23H21ClN4O
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0566568
|
2-(4-chlorophenyl)-5-[2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]ethynyl]pyridine
Show/Hide
|
C25H23ClN2O
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0553806
|
US8933079, 3.1
Show/Hide
|
C27H31ClN4O3
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0531646
|
US8933079, 7.17
Show/Hide
|
C24H26ClN5O3
|
1
|
| 1 |
IC50 = 83 nM
|
|
|
|
CP0443107
|
US8933079, 3.5
Show/Hide
|
C26H29ClN4O3
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
|
CP0518557
|
US8933079, 2.3
Show/Hide
|
C26H28FN3O4
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0531729
|
US8933079, 2.2
Show/Hide
|
C26H28FN3O3
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0565570
|
US8933079, 2.6
Show/Hide
|
C23H24FN3O3
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0487092
|
N,N-diethyl-2-[4-[2-[5-(4-methoxyphenyl)pyrimidin-2-yl]ethynyl]phenoxy]ethanamine
Show/Hide
|
C25H27N3O2
|
1
|
| 1 |
IC50 = 149 nM
|
|
|
|
CP0487091
|
N,N-diethyl-2-[4-[2-[4-(4-methoxyphenyl)phenyl]ethynyl]phenoxy]ethanamine
Show/Hide
|
C27H29NO2
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
|
CP0494766
|
4-[2-(diethylamino)ethoxy]-N-[4-(4-methoxyphenyl)phenyl]-N-methylbenzamide
Show/Hide
|
C27H32N2O3
|
1
|
| 1 |
IC50 = 251 nM
|
|
|
|
CP0400479
|
N,N-diethyl-2-[4-[2-[5-(4-methoxyphenyl)pyridin-2-yl]ethyl]phenoxy]ethanamine
Show/Hide
|
C26H32N2O2
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0534573
|
N,N-diethyl-2-[4-[(E)-2-[5-(4-methoxyphenyl)pyridin-2-yl]ethenyl]phenoxy]ethanamine
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0494760
|
5-[2-[[4-(4-chlorophenyl)benzoyl]amino]ethyl]-2-(pyrrolidin-1-ylmethyl)benzamide
Show/Hide
|
C27H28ClN3O2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0530327
|
N,N-diethyl-2-[4-[(Z)-2-[5-(4-methoxyphenyl)pyridin-2-yl]ethenyl]phenoxy]ethanamine
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
