| Compound ID |
Compound Name |
Compound Formula |
|
CP0395808
|
N-[[6-[2-(4-methyloxan-4-yl)acetyl]-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
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|
C24H34N4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0395809
|
(3-methyloxetan-3-yl) (2S)-2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H28N4O4
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0156217
|
APO-866
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|
C24H29N3O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0318689
|
GMX1778
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|
C19H22ClN5O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0456150
|
tert-butyl (2S)-2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H30N4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0848279
|
(+/-)-3-Methyloxetan-3-yl1-((2,3-Dihydro-1H-pyrrolo[3,4-c]-pyridine-2-carboxamido-1,1,3,3-d4)methyl)-6-azaspiro[2.5]-octane-6-carboxylate
Show/Hide
|
C21H28N4O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0374577
|
tert-butyl 2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H30N4O3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0406347
|
N-[[6-(3,3-dimethylbutanoyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C22H32N4O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0563738
|
(1-methoxy-2-methylpropan-2-yl) 2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
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|
C22H32N4O4
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0856631
|
(+/-)-N-((6-(2,4-Dimethyloxazole-5-carbonyl)-6-azaspiro[2.5]-octan-1-yl)methyl)-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxamide
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0054091
|
N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide
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|
C21H15F2N3O3S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0380025
|
(3-methyloxetan-3-yl) 2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H28N4O4
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0374579
|
N-[(6-benzoyl-6-azaspiro[2.5]octan-2-yl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
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|
C23H26N4O2
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0563737
|
N-[[6-(2,4-dimethyl-1,3-thiazole-5-carbonyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C22H27N5O2S
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0278283
|
N-[[4-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
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|
C21H15F3N4O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0519180
|
N-[[6-(1,5-dimethylpyrazole-4-carbonyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0380027
|
propan-2-yl 2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C20H28N4O3
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0395821
|
N-[[6-(3-methylbutanoyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C21H30N4O2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0534682
|
(1-methylcyclobutyl) 2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0088762
|
N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C21H15F2N3O3S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0517992
|
N-[[6-[4-(1-methylpiperidin-4-yl)benzoyl]-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C29H37N5O2
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0456146
|
N-[[6-[3-(oxan-4-yl)propanoyl]-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C24H34N4O3
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0116768
|
N-[[5-(3,5-difluorophenyl)sulfonylpyridin-2-yl]methyl]furo[2,3-c]pyridine-2-carboxamide
Show/Hide
|
C20H13F2N3O4S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0374574
|
N-[[5-[(S)-(3,5-difluorophenyl)sulfinyl]pyridin-2-yl]methyl]furo[2,3-c]pyridine-2-carboxamide
Show/Hide
|
C20H13F2N3O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0514535
|
(1S,2S)-N-[4-(benzenesulfonyl)phenyl]-2-pyridin-3-ylcyclopropane-1-carboxamide
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|
C21H18N2O3S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0504074
|
N-[[6-(1,3,5-trimethylpyrazole-4-carbonyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C23H30N6O2
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0380024
|
N-[[6-(4-methylpyridine-3-carbonyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0447475
|
N-[[6-[2-(oxan-4-yl)acetyl]-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C23H32N4O3
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0406348
|
N-[[6-(1,3-dimethylpyrazole-4-carbonyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C22H28N6O2
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0222543
|
N-[[4-(benzenesulfonyl)phenyl]methyl]furo[2,3-c]pyridine-2-carboxamide
Show/Hide
|
C21H16N2O4S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0072087
|
N-[[5-(1-propan-2-ylpyrazol-4-yl)sulfonylpyridin-2-yl]methyl]furo[2,3-c]pyridine-2-carboxamide
Show/Hide
|
C20H19N5O4S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0294978
|
N-[[4-(6-methylpyridin-3-yl)sulfonylphenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0451499
|
N-[[6-[2-(3-methyloxetan-3-yl)acetyl]-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C22H30N4O3
|
1
|
| 1 |
IC50 = 11.2 nM
|
|
|
|
CP0406346
|
N-[(4-cyclohexylsulfonylphenyl)methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C21H25N3O3S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0451607
|
N-[[6-[2-(3-hydroxy-3-methylcyclobutyl)acetyl]-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C23H32N4O3
|
1
|
| 1 |
IC50 = 13.3 nM
|
|
|
|
CP0051758
|
N-[[4-(benzenesulfonyl)phenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C21H19N3O3S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0456149
|
N-[[4-[[3-(dimethylcarbamoyl)phenyl]methoxy]phenyl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0456147
|
N-[[6-(tert-butylcarbamoyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C21H31N5O2
|
1
|
| 1 |
IC50 = 20.7 nM
|
|
|
|
CP0374578
|
N-[[6-(4,4,4-trifluorobutanoyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C20H25F3N4O2
|
1
|
| 1 |
IC50 = 24.8 nM
|
|
|
|
CP0395819
|
N-[[4-(cyclopentylsulfonylamino)phenyl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C20H22N4O3S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
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CP0573489
|
ethyl 2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C19H26N4O3
|
1
|
| 1 |
IC50 = 29.4 nM
|
|
|
|
CP0374580
|
N-[[6-(2-pyrimidin-2-ylacetyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C22H26N6O2
|
1
|
| 1 |
IC50 = 31.2 nM
|
|
|
|
CP0108645
|
1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
Show/Hide
|
C19H22N4O4S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
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CP0504073
|
tert-butyl (2R)-2-[(1,3-dihydropyrrolo[3,4-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H30N4O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0454707
|
tert-butyl 2-[(furo[2,3-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H27N3O4
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0374575
|
6-amino-N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C21H16F2N4O3S
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0109097
|
1-[(6-aminopyridin-3-yl)methyl]-3-[4-(benzenesulfonyl)phenyl]urea
Show/Hide
|
C19H18N4O3S
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0517991
|
tert-butyl 2-[(imidazo[1,2-a]pyrimidine-6-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C20H27N5O3
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0052042
|
1-[4-(2,8-diazaspiro[4.5]decan-8-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
Show/Hide
|
C21H27N5O3S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0504072
|
tert-butyl 2-[(1H-pyrrolo[3,2-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0451481
|
tert-butyl 2-[(imidazo[1,2-a]pyridine-6-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H28N4O3
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
|
CP0052046
|
1-[4-(benzenesulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
Show/Hide
|
C19H17N3O3S
|
1
|
| 1 |
IC50 = 144 nM
|
|
|
|
CP0447510
|
tert-butyl 2-[(thieno[2,3-c]pyridine-2-carbonylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C21H27N3O3S
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0313994
|
6-amino-N-[[4-(benzenesulfonyl)phenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
IC50 = 378 nM
|
|
|
|
CP0573488
|
N-[[6-(2-phenylethyl)-6-azaspiro[2.5]octan-2-yl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
IC50 = 753.5 nM
|
|
|
|
CP0456143
|
5-amino-N-[[4-(benzenesulfonyl)phenyl]methyl]furo[2,3-c]pyridine-2-carboxamide
Show/Hide
|
C21H17N3O4S
|
1
|
| 1 |
IC50 = 828 nM
|
|
|
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CP0109064
|
1-[4-(benzenesulfonyl)phenyl]-3-[(6-methylpyridin-3-yl)methyl]urea
Show/Hide
|
C20H19N3O3S
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
|
CP0447509
|
N-[(4-sulfamoylphenyl)methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C15H14N4O3S
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
|
CP0456144
|
N-(cyclohexylmethyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C15H19N3O
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
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CP0456145
|
tert-butyl 2-[(pyridin-3-ylmethylcarbamoylamino)methyl]-6-azaspiro[2.5]octane-6-carboxylate
Show/Hide
|
C20H30N4O3
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
|
CP0456148
|
N-[(4-methylsulfonylphenyl)methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C16H15N3O3S
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
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CP0504075
|
N-[[4-(pyrrolidine-1-carbonyl)phenyl]methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
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CP0517989
|
N-(2-methylpropyl)-1H-pyrrolo[3,2-c]pyridine-2-carboxamide
Show/Hide
|
C12H15N3O
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
