Brief Information of the Compound and Protein
Compound Name
6-amino-N-[[4-(benzenesulfonyl)phenyl]methyl]-1,3-dihydropyrrolo[3,4-c]pyridine-2-carboxamide
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PubChem ID
CID: 71727934
Canonical SMILES
Nc1cc2CN(Cc2cn1)C(=O)NCc1ccc(cc1)S(=O)(=O)c1ccccc1
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Compound Formula C21H20N4O3S
Compound Structure
Protein Name
Nicotinamide phosphoribosyltransferase
Protein Classification
Enzyme
Uniprot ID
P43490
Gene Name
NAMPT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  1
1
IC50 = 378 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 75 nM