Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-(2,8-diazaspiro[4.5]decan-8-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
    Show/Hide
 PubChem ID
CID: 71654852
Canonical SMILES
O=C(NCc1cccnc1)Nc1ccc(cc1)S(=O)(=O)N1CCC2(CCNC2)CC1
    Show/Hide
Compound Formula C21H27N5O3S
Compound Structure
Protein Name
 Protein Info 
Nicotinamide phosphoribosyltransferase
Protein Classification
Enzyme
Uniprot ID
P43490
Gene Name
NAMPT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM