Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl]-3-(pyridin-3-ylmethyl)urea
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 PubChem ID
CID: 66611375
Canonical SMILES
O=C(NCc1cccnc1)Nc1ccc(cc1)S(=O)(=O)N1CC2CCC(C1)O2
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Compound Formula C19H22N4O4S
Compound Structure
Protein Name
 Protein Info 
Nicotinamide phosphoribosyltransferase
Protein Classification
Enzyme
Uniprot ID
P43490
Gene Name
NAMPT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7 nM
2 IC50 = 10 nM
3 IC50 = 13 nM
4 IC50 = 19 nM
5 IC50 = 83 nM
6 IC50 = 171 nM