Brief Information of the Compound and Protein
Compound Name
(+/-)-N-((6-(2,4-Dimethyloxazole-5-carbonyl)-6-azaspiro[2.5]-octan-1-yl)methyl)-1H-pyrrolo[3,4-c]pyridine-2(3H)-carboxamide
    Show/Hide
PubChem ID
CID: 118621271
Canonical SMILES
Cc1nc(C)c(C(=O)N2CCC3(CC2)CC3CNC(=O)N2Cc3ccncc3C2)o1
    Show/Hide
Compound Formula C22H27N5O3
Compound Structure
Protein Name
Nicotinamide phosphoribosyltransferase
Protein Classification
Enzyme
Uniprot ID
P43490
Gene Name
NAMPT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  1
1
IC50 = 1.6 nM
   TI
   LI
   LO
   TS