| Compound ID |
Compound Name |
Compound Formula |
|
CP0355792
|
6-(2-aminopyrimidin-5-yl)-N-[6-(1-methylpiperidin-4-yl)oxypyridin-3-yl]-2-morpholin-4-ylpyrimidin-4-amine
Show/Hide
|
C23H29N9O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0067162
|
2-morpholino-N6-(quinolin-3-yl)-4,5'-bipyrimidine-2',6-diamine
Show/Hide
|
C21H20N8O
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0066324
|
N-[6-[6-amino-5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-b]pyridazin-2-yl]acetamide
Show/Hide
|
C14H11F3N6O
|
1
|
| 1 |
EC50 < 40 nM
|
|
|
|
CP0074362
|
N-[6-(5-amino-6-ethoxypyrazin-2-yl)imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C15H16N6O2
|
1
|
| 1 |
EC50 < 40 nM
|
|
|
|
CP0074363
|
N-[6-(6-amino-5-ethoxypyridin-3-yl)imidazo[1,2-b]pyridazin-2-yl]acetamide
Show/Hide
|
C15H16N6O2
|
1
|
| 1 |
EC50 < 40 nM
|
|
|
|
CP0099482
|
N-[6-[5-amino-6-(1,1,1-trifluoropropan-2-yloxy)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C16H15F3N6O2
|
1
|
| 1 |
EC50 < 40 nM
|
|
|
|
CP0133918
|
N-[6-[5-amino-6-(2,2,2-trifluoroethoxy)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C15H13F3N6O2
|
1
|
| 1 |
EC50 < 40 nM
|
|
|
|
CP0403436
|
N-[6-(5-amino-6-propan-2-yloxypyrazin-2-yl)imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C16H18N6O2
|
1
|
| 1 |
EC50 < 40 nM
|
|
|
|
CP0067896
|
N-[6-(5-amino-6-methoxypyrazin-2-yl)imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C14H14N6O2
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0044152
|
N-[6-[6-amino-5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C15H12F3N5O
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0057731
|
6-(2-aminopyrimidin-5-yl)-N-(6-methoxypyridin-3-yl)-2-morpholin-4-ylpyrimidin-4-amine
Show/Hide
|
C18H20N8O2
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0455105
|
N-[6-(6-amino-5-methoxypyridin-3-yl)imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C15H15N5O2
|
1
|
| 1 |
EC50 = 90 nM
|
|
|
|
CP0067148
|
2-morpholino-N6-(6-phenoxypyridin-3-yl)-4,5'-bipyrimidine-2',6-diamine
Show/Hide
|
C23H22N8O2
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0267762
|
N-[6-[2-(methylamino)pyrimidin-5-yl]-2-morpholin-4-ylpyrimidin-4-yl]quinolin-3-amine
Show/Hide
|
C22H22N8O
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0350954
|
N-[6-(6-amino-5-methoxypyridin-3-yl)imidazo[1,2-b]pyridazin-2-yl]acetamide
Show/Hide
|
C14H14N6O2
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0014549
|
2-morpholino-4,5'-bipyrimidin-2'-amine
Show/Hide
|
C12H14N6O
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0350953
|
N-[6-[6-amino-5-(2-methoxyethoxy)pyridin-3-yl]imidazo[1,2-b]pyridazin-2-yl]acetamide
Show/Hide
|
C16H18N6O3
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0429707
|
N-[6-[5-amino-6-(2-methoxyethoxy)pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C16H18N6O3
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0353573
|
2-morpholino-N6-(tetrahydro-2H-pyran-4-yl)-4,5'-bipyrimidine-2',6-diamine
Show/Hide
|
C17H23N7O2
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0447635
|
N-[6-(6-amino-5-ethoxypyridin-3-yl)imidazo[1,2-a]pyridin-2-yl]acetamide
Show/Hide
|
C16H17N5O2
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0355469
|
N-[6-(6-aminopyridin-3-yl)-2-morpholin-4-ylpyrimidin-4-yl]quinolin-3-amine
Show/Hide
|
C22H21N7O
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0264752
|
3-(2-morpholino-6-(quinolin-3-ylamino)pyrimidin-4-yl)phenol
Show/Hide
|
C23H21N5O2
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0287208
|
N-(2-morpholin-4-yl-6-pyrazin-2-ylpyrimidin-4-yl)quinolin-3-amine
Show/Hide
|
C21H19N7O
|
1
|
| 1 |
EC50 = 390 nM
|
|
|
|
CP0492328
|
N-(2-morpholin-4-yl-6-pyrimidin-5-ylpyrimidin-4-yl)quinolin-3-amine
Show/Hide
|
C21H19N7O
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0492327
|
N-(2-morpholin-4-yl-6-pyridin-3-ylpyrimidin-4-yl)quinolin-3-amine
Show/Hide
|
C22H20N6O
|
1
|
| 1 |
EC50 = 650 nM
|
|
|
|
CP0322007
|
N-[6-(5-aminopyrazin-2-yl)-2-morpholin-4-ylpyrimidin-4-yl]quinolin-3-amine
Show/Hide
|
C21H20N8O
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
