Brief Information of the Compound and Protein
Compound Name
N-[6-(6-amino-5-ethoxypyridin-3-yl)imidazo[1,2-b]pyridazin-2-yl]acetamide
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PubChem ID
CID: 59251850
Canonical SMILES
CCOc1cc(cnc1N)-c1ccc2nc(NC(C)=O)cn2n1
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Compound Formula C15H16N6O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  1
1
EC50 < 40 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11 nM