Brief Information of the Compound and Protein
Compound Name
2-morpholino-N6-(tetrahydro-2H-pyran-4-yl)-4,5'-bipyrimidine-2',6-diamine
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PubChem ID
CID: 53318782
Canonical SMILES
Nc1ncc(cn1)-c1cc(NC2CCOCC2)nc(n1)N1CCOCC1
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Compound Formula C17H23N7O2
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM