Brief Information of the Compound and Protein
Compound Name
N-[6-[6-amino-5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridin-2-yl]acetamide
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PubChem ID
CID: 59251679
Canonical SMILES
CC(=O)Nc1cn2cc(ccc2n1)-c1cnc(N)c(c1)C(F)(F)F
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Compound Formula C15H12F3N5O
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42336
Gene Name
PIK3CA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780 Homo sapiens (Human)  1
1
EC50 = 80 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.6 nM
2 IC50 = 4 nM
3 IC50 = 5.9 nM
4 IC50 = 12 nM