Brief Information of the Cell Line and Protein
Cell Line ID: CL000058 , T-REx-293
Synonyms
T-REx 293
T-REx293
TRex-293
TREx293
T-REx-HEK293
T-REx HEK 293
HEK293-T-REx
HEK293-Trex
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_D585
Protein ID: PT02149 , Transient receptor potential cation channel subfamily A member 1
Gene Name TRPA1
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID O75762
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000058  Protein ID: PT02149
 
Compound ID Compound Name Compound Formula
CP0274724
methyl benzo[b][1,4]benzoxazepine-10-carboxylate
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C15H11NO3
 5
1
EC50 = 0.05 nM
   TI
   LI
   LO
   TS
2
EC50 = 7.413 nM
   TI
   LI
   LO
   TS
3
EC50 = 23.99 nM
   TI
   LI
   LO
   TS
4
EC50 = 83.18 nM
   TI
   LI
   LO
   TS
5
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
CP0238232
benzo[b][1,4]benzoxazepine-10-carboxamide
   Show/Hide
C14H10N2O2
 1
1
EC50 = 0.08 nM
   TI
   LI
   LO
   TS
CP0236431
11H-Dibenzo[b,e]-azepine-10-carboxylic Acid Methyl Ester
   Show/Hide
C16H13NO2
 5
1
EC50 = 0.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 4.365 nM
   TI
   LI
   LO
   TS
3
EC50 = 9.772 nM
   TI
   LI
   LO
   TS
4
EC50 = 38.02 nM
   TI
   LI
   LO
   TS
5
EC50 = 72.44 nM
   TI
   LI
   LO
   TS
CP0379388
benzo[b][1,4]benzoxazepine-1-carbonitrile
   Show/Hide
C14H8N2O
 1
1
EC50 = 0.1 nM
   TI
   LI
   LO
   TS
CP0236432
benzo[b][1,4]benzoxazepine-1-carboxamide
   Show/Hide
C14H10N2O2
 1
1
EC50 = 0.11 nM
   TI
   LI
   LO
   TS
CP0379387
benzo[b][1,4]benzoxazepine-10-carbonitrile
   Show/Hide
C14H8N2O
 1
1
EC50 = 0.15 nM
   TI
   LI
   LO
   TS
CP0096071
benzo[b][1,4]benzoxazepine
   Show/Hide
C13H9NO
 1
1
EC50 = 0.3 nM
   TI
   LI
   LO
   TS
CP0278519
11H-dibenzo[b,e]azepine-2-carboxylic acid methyl ester
   Show/Hide
C16H13NO2
 1
1
EC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0107397
11H-Dibenzo[b,e]azepine-1-carboxylic acid methyl ester
   Show/Hide
C16H13NO2
 1
1
EC50 = 0.6 nM
   TI
   LI
   LO
   TS
CP0388610
2-chlorobenzylidenemalononitrile
   Show/Hide
C10H5ClN2
 1
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
CP0871687
11H-Dibenzo[b,e]azepine-10-carbonitrile hydrochloride
   Show/Hide
C15H11ClN2
 1
1
EC50 = 1.6 nM
   TI
   LI
   LO
   TS
CP0388609
benzo[b][1,4]benzoxazepin-9-ol
   Show/Hide
C13H9NO2
 1
1
EC50 = 2.1 nM
   TI
   LI
   LO
   TS
CP0388608
11H-Dibenzo[b,e]azepine-10-carboxylic amide
   Show/Hide
C15H12N2O
 1
1
EC50 = 2.5 nM
   TI
   LI
   LO
   TS
CP0278518
11H-dibenzo[b,e]azepine
   Show/Hide
C14H11N
 1
1
EC50 = 3 nM
   TI
   LI
   LO
   TS
CP0919006
10-Bromo-11H-dibenzo[b,e]azepine hydrochloride
   Show/Hide
C14H11BrClN
 1
1
EC50 = 3.5 nM
   TI
   LI
   LO
   TS
CP0068061
methyl benzo[b][1,4]benzoxazepine-9-carboxylate
   Show/Hide
C15H11NO3
 1
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
CP0919008
11H-dibenzo[b,e]azepine-10-carboxylic acid butyl ester hydrochloride
   Show/Hide
C19H20ClNO2
 1
1
EC50 = 6.2 nM
   TI
   LI
   LO
   TS
CP0860804
11H-Dibenzo[b,e]azepine-10-carboxylic acid(3-methoxy-propyl)-amide hydrochloride
   Show/Hide
C19H21ClN2O2
 1
1
EC50 = 7.7 nM
   TI
   LI
   LO
   TS
CP0405411
benzo[b][1,4]benzothiazepine
   Show/Hide
C13H9NS
 1
1
EC50 = 9 nM
   TI
   LI
   LO
   TS
CP0226195
2-bromo-2-phenylacetonitrile
   Show/Hide
C8H6BrN
 1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS
CP0379389
3-methoxydibenzo[b,f][1,4]oxazepine
   Show/Hide
C14H11NO2
 1
1
EC50 = 14 nM
   TI
   LI
   LO
   TS
CP0425863
11H-Dibenzo[b,e]azepine-3-carboxylic acid methyl ester
   Show/Hide
C16H13NO2
 1
1
EC50 = 19 nM
   TI
   LI
   LO
   TS
CP0095800
2-chloro-1-phenylethan-1-one
   Show/Hide
C8H7ClO
 1
1
EC50 = 30 nM
   TI
   LI
   LO
   TS
CP0379386
11H-dibenzo[b,e]azepine-4-carboxylic acid methyl ester
   Show/Hide
C16H13NO2
 1
1
EC50 = 31 nM
   TI
   LI
   LO
   TS
CP0519928
11H-Dibenzo[b,e]azepine-7-carboxylic acid methyl ester
   Show/Hide
C16H13NO2
 1
1
EC50 = 31 nM
   TI
   LI
   LO
   TS
CP0388601
8-Bromo-11H-dibenzo[b,e]azepine
   Show/Hide
C14H10BrN
 1
1
EC50 = 33 nM
   TI
   LI
   LO
   TS
CP0375628
11H-Dibenzo[b,e]azepine-10-carboxylic acid diethylamide
   Show/Hide
C19H20N2O
 1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0386158
11H-dibenzo[b,e]azepine-8-carboxylic Acid MethylEster
   Show/Hide
C16H13NO2
 1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
CP0479545
11H-dibenzo[b,e]azepine-8-carbonitrile
   Show/Hide
C15H10N2
 1
1
EC50 = 158 nM
   TI
   LI
   LO
   TS
CP0425866
11H-Dibenzo[b,e]azepine-10-carboxylic acid
   Show/Hide
C15H11NO2
 1
1
EC50 = 245 nM
   TI
   LI
   LO
   TS
CP0105333
(isothiocyanatomethyl)benzene
   Show/Hide
C8H7NS
 5
1
EC50 = 250 nM
   TI
   LI
   LO
   TS
2
EC50 = 10964.78 nM
   TI
   LI
   LO
   TS
3
EC50 = 15488.17 nM
   TI
   LI
   LO
   TS
4
EC50 = 23988.33 nM
   TI
   LI
   LO
   TS
5
EC50 = 27542.29 nM
   TI
   LI
   LO
   TS
CP0395927
4-isothiocyanatobut-1-ene
   Show/Hide
C5H7NS
 1
1
EC50 = 360 nM
   TI
   LI
   LO
   TS
CP0000476
(2-Isothiocyanato-ethyl)-benzene
   Show/Hide
C9H9NS
 1
1
EC50 = 370 nM
   TI
   LI
   LO
   TS
CP0041478
3-isothiocyanatoprop-1-ene
   Show/Hide
C4H5NS
 6
1
EC50 = 398 nM
   TI
   LI
   LO
   TS
2
EC50 = 580 nM
   TI
   LI
   LO
   TS
3
EC50 = 5754.4 nM
   TI
   LI
   LO
   TS
4
EC50 = 10471.29 nM
   TI
   LI
   LO
   TS
5
EC50 = 12022.64 nM
   TI
   LI
   LO
   TS
6
EC50 = 22387.21 nM
   TI
   LI
   LO
   TS
CP0122307
Erucin
   Show/Hide
C6H11NS2
 1
1
EC50 = 420 nM
   TI
   LI
   LO
   TS
CP0380552
1-isothiocyanato-3-methylsulfanylpropane
   Show/Hide
C5H9NS2
 1
1
EC50 = 450 nM
   TI
   LI
   LO
   TS
CP0456234
1-isothiocyanato-5-methylsulfanylpentane
   Show/Hide
C7H13NS2
 1
1
EC50 = 500 nM
   TI
   LI
   LO
   TS
CP0882678
isopropyl isothiocyanate
   Show/Hide
C4H7NS
 1
1
EC50 = 530 nM
   TI
   LI
   LO
   TS
CP0418232
5-isothiocyanatopent-1-ene
   Show/Hide
C6H9NS
 1
1
EC50 = 540 nM
   TI
   LI
   LO
   TS
CP0395928
1-isothiocyanato-6-methylsulfanylhexane
   Show/Hide
C8H15NS2
 1
1
EC50 = 580 nM
   TI
   LI
   LO
   TS
CP0418231
1-isothiocyanato-7-methylsulfanylheptane
   Show/Hide
C9H17NS2
 1
1
EC50 = 610 nM
   TI
   LI
   LO
   TS
CP0848559
2-isothiocyanatobutane
   Show/Hide
C5H9NS
 1
1
EC50 = 680 nM
   TI
   LI
   LO
   TS
CP0456235
1-isothiocyanato-2-methylpropane
   Show/Hide
C5H9NS
 1
1
EC50 = 690 nM
   TI
   LI
   LO
   TS
CP0388602
11H-dibenzo[b,e]azepine-8-carboxylic acid isopropyl ester
   Show/Hide
C18H17NO2
 1
1
EC50 = 933 nM
   TI
   LI
   LO
   TS
CP0380517
6-isothiocyanatohex-1-ene
   Show/Hide
C7H11NS
 1
1
EC50 = 1040 nM
   TI
   LI
   LO
   TS
CP0444594
7-isothiocyanatohept-1-ene
   Show/Hide
C8H13NS
 1
1
EC50 = 1050 nM
   TI
   LI
   LO
   TS
CP0126907
methyl (1S,15S,17S,18S)-17-ethyl-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate
   Show/Hide
C22H28N2O3
 1
1
EC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0857633
dihydrocatharanthine
   Show/Hide
C21H26N2O2
 1
1
EC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0114241
methyl (1R,15R,18R)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate
   Show/Hide
C21H24N2O2
 1
1
EC50 = 9000 nM
   TI
   LI
   LO
   TS
CP0126906
methyl (1S,15S,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
   Show/Hide
C21H26N2O2
 1
1
EC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0380518
4-(isothiocyanatomethyl)phenol
   Show/Hide
C8H7NOS
 1
1
EC50 = 20000 nM
   TI
   LI
   LO
   TS
CP0389161
methyl (1S,14R,16S,17S)-16-ethyl-7-methoxy-3-(methoxymethyl)-10,12-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2,4(9),5,7-tetraene-1-carboxylate
   Show/Hide
C23H30N2O4
 1
1
EC50 = 26000 nM
   TI
   LI
   LO
   TS
CP0311436
19(S)-Heyneanine
   Show/Hide
C22H28N2O4
 1
1
EC50 = 30000 nM
   TI
   LI
   LO
   TS
CP0389160
methyl (1S,10S,15R,17S,18S)-17-ethyl-10-hydroxy-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2,4(9),5,7-tetraene-1-carboxylate
   Show/Hide
C22H28N2O4
 1
1
EC50 = 32000 nM
   TI
   LI
   LO
   TS
CP0851507
Voacanginol
   Show/Hide
C21H28N2O2
 1
1
EC50 = 42000 nM
   TI
   LI
   LO
   TS
CP0846028
3-oxovoacangine
   Show/Hide
C22H26N2O4
 1
1
EC50 = 78000 nM
   TI
   LI
   LO
   TS
CP0369412
1-(4-chlorophenyl)-N-[2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]-3-phenylpropyl]cyclopentane-1-carboxamide
   Show/Hide
C27H32ClF3N2O2
 2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
IC50 = 374 nM
   TI
   LI
   LO
   TS
CP0504378
1-(4-chlorophenyl)-N-[3-(4-fluorophenyl)-2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]propyl]cyclopropane-1-carboxamide
   Show/Hide
C25H27ClF4N2O2
 1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS
CP0551326
1-(4-fluorophenyl)-N-[2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]-3-phenylpropyl]cyclohexane-1-carboxamide
   Show/Hide
C28H34F4N2O2
 1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
CP0445803
1-(4-chlorophenyl)-N-[3-phenyl-2-[4-(trifluoromethyl)piperidin-1-yl]propyl]cyclopentane-1-carboxamide
   Show/Hide
C27H32ClF3N2O
 1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0420617
N-[3-(4-bromophenyl)-2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]propyl]-1-(4-chlorophenyl)cyclopentane-1-carboxamide
   Show/Hide
C27H31BrClF3N2O2
 1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0469579
1-(4-chlorophenyl)-N-[2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]-3-phenylpropyl]cyclopropane-1-carboxamide
   Show/Hide
C25H28ClF3N2O2
 1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CP0561896
N-[2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]-3-phenylpropyl]-2-methyl-2-phenylpropanamide
   Show/Hide
C25H31F3N2O2
 1
1
IC50 = 43 nM
   TI
   LI
   LO
   TS
CP0561895
1-(4-chlorophenyl)-N-[3-(4-cyanophenyl)-2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]propyl]cyclopentane-1-carboxamide
   Show/Hide
C28H31ClF3N3O2
 1
1
IC50 = 63 nM
   TI
   LI
   LO
   TS
CP0958747
(R)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)-2,2-dimethylpentanamide
   Show/Hide
C22H33F3N2O2
 1
1
IC50 = 71 nM
   TI
   LI
   LO
   TS
CP0492521
N-[3-(ethylamino)-5-(trifluoromethyl)phenyl]-2,6-difluorobenzamide
   Show/Hide
C16H13F5N2O
 1
1
IC50 = 74 nM
   TI
   LI
   LO
   TS
CP0523041
2,6-difluoro-N-[3-(propan-2-ylamino)-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C17H15F5N2O
 1
1
IC50 = 91 nM
   TI
   LI
   LO
   TS
CP0410395
2,6-difluoro-N-[3-(propylamino)-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C17H15F5N2O
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0556496
N-[3-(propylamino)-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C17H17F3N2O
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0481848
N-[3-(propan-2-ylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C15H15F3N2OS
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0433305
4-(4-fluorophenoxy)-1H-pyrrolo[3,2-c]pyridine
   Show/Hide
C13H9FN2O
 1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS
CP0247036
4-(2,4-difluorophenoxy)-1H-pyrrolo[3,2-c]pyridine
   Show/Hide
C13H8F2N2O
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0247044
1-(4-fluorophenoxy)-6,7-dimethoxyisoquinoline
   Show/Hide
C17H14FNO3
 1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0428150
N-[3-(propylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C15H15F3N2OS
 1
1
IC50 = 390 nM
   TI
   LI
   LO
   TS
CP0208423
4-(4-fluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H8FN3O
 1
1
IC50 = 410 nM
   TI
   LI
   LO
   TS
CP0433306
1-(2,4-difluorophenoxy)-6,7-dimethoxyisoquinoline
   Show/Hide
C17H13F2NO3
 1
1
IC50 = 630 nM
   TI
   LI
   LO
   TS
CP0510596
5-chloro-4-(2,4-difluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H6ClF2N3O
 1
1
IC50 = 630 nM
   TI
   LI
   LO
   TS
CP0433307
4-(2,4-difluorophenoxy)-5-methyl-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H9F2N3O
 1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0554526
4-(2,4-difluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H7F2N3O
 1
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
CP0492519
N-[3-(2-methylpropylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C16H17F3N2OS
 1
1
IC50 = 790 nM
   TI
   LI
   LO
   TS
CP0537542
N-[3-(propylamino)-5-(trifluoromethyl)phenyl]pyridine-3-carboxamide
   Show/Hide
C16H16F3N3O
 1
1
IC50 = 940 nM
   TI
   LI
   LO
   TS
CP0400810
4-(2,4-difluorophenoxy)-1H-indole
   Show/Hide
C14H9F2NO
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0553522
7-(2,4-difluorophenoxy)furo[2,3-c]pyridine
   Show/Hide
C13H7F2NO2
 1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CP0467211
4-(2,4-difluorophenoxy)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H9F2N3O
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0553523
4-(2,4-difluorophenoxy)-6,7-dimethoxyquinazoline
   Show/Hide
C16H12F2N2O3
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0523040
3,4-difluoro-N-[3-(propylamino)-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C17H15F5N2O
 1
1
IC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0469152
1-(2,4-difluorophenoxy)-6-methoxyisoquinoline
   Show/Hide
C16H11F2NO2
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0527851
N-[3-(3-methylbutan-2-ylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C17H19F3N2OS
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0545785
4-fluoro-N-[3-(propylamino)-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C17H16F4N2O
 1
1
IC50 = 1400 nM
   TI
   LI
   LO
   TS
CP0742542
(R)-1-(4-chlorophenyl)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)cyclopentanecarboxamide
   Show/Hide
C27H32ClF3N2O2
 1
1
IC50 = 1578 nM
   TI
   LI
   LO
   TS
CP0556699
4-(2,4-difluorophenoxy)-5-ethyl-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C14H11F2N3O
 1
1
IC50 = 1600 nM
   TI
   LI
   LO
   TS
CP0931361
(S)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)-2,2-dimethylpentanamide
   Show/Hide
C22H33F3N2O2
 1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0410396
2,6-difluoro-N-[3-methyl-5-(propylamino)phenyl]benzamide
   Show/Hide
C17H18F2N2O
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0567055
4-(2,4-difluorophenoxy)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C14H11F2N3O
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0433308
4-(2,4-difluorophenoxy)furo[3,2-c]pyridine
   Show/Hide
C13H7F2NO2
 1
1
IC50 = 2200 nM
   TI
   LI
   LO
   TS
CP0513076
methyl N-[3-(thiophene-2-carbonylamino)-5-(trifluoromethyl)phenyl]carbamate
   Show/Hide
C14H11F3N2O3S
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0543204
4-(2,4-difluorophenoxy)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H6F2IN3O
 1
1
IC50 = 2500 nM
   TI
   LI
   LO
   TS
CP0452830
N-[3-(propylamino)-5-(trifluoromethyl)phenyl]pyridine-4-carboxamide
   Show/Hide
C16H16F3N3O
 1
1
IC50 = 2600 nM
   TI
   LI
   LO
   TS
CP0562188
4-(2,3-difluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H7F2N3O
 1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0452828
N-[3-(thiophen-2-ylmethylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C17H13F3N2OS2
 1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0452829
N-[3-(benzylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C19H15F3N2OS
 1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0546416
4-(2,4-difluorophenoxy)-7-methoxyquinazoline
   Show/Hide
C15H10F2N2O2
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0554527
4-(3,4-difluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H7F2N3O
 1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0384933
1-(2,4-difluorophenoxy)isoquinoline
   Show/Hide
C15H9F2NO
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0461576
4-phenoxy-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H9N3O
 1
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
CP0527850
N-[3-(2-phenylethylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C20H17F3N2OS
 1
1
IC50 = 3900 nM
   TI
   LI
   LO
   TS
CP0898989
rac-1-(4-fluorophenyl)-N-(3-(4-fluorophenyl)-2-(3-hydroxypyrrolidin-1-yl)propyl)cyclopentanecarboxamide
   Show/Hide
C25H30F2N2O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0906487
rac-N-(2-(2-azabicyclo[2.2.1]heptan-2-yl)-3-(4-fluorophenyl)propyl)-1-(4-fluorophenyl)cyclopropanecarboxamide
   Show/Hide
C25H28F2N2O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0924848
rac-1-(4-fluorophenyl)-N-(3-(4-fluorophenyl)-2-(2-oxo-1,8-diazaspiro[4.5]decan-8-yl)propyl)cyclopropanecarboxamide
   Show/Hide
C27H31F2N3O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0934514
rac-N-(2-(1,1-difluoro-5-azaspiro[2.4]heptan-5-yl)-3-(4-fluorophenyl)propyl)-1-(4-fluorophenyl)cyclopentanecarboxamide
   Show/Hide
C27H30F4N2O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0948691
Rac-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)-2-methyl-5-(trifluoromethyl)oxazole-4-carboxamide
   Show/Hide
C21H23F6N3O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0958837
Rac-2-(4-tert-butylphenyl)-N-(2-(4-hydroxy-4-(trifluoromethyl)piperidin-1-yl)-3-phenylpropyl)acetamide
   Show/Hide
C27H35F3N2O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0961956
rac-1-(4-fluorophenyl)-N-(3-(4-fluorophenyl)-2-(2-oxa-7-azaspiro[3.5]nonan-7-yl)propyl)cyclopentanecarboxamide
   Show/Hide
C28H34F2N2O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0395866
4-(2,4-difluorophenoxy)-1H-pyrrolo[2,3-b]pyridine
   Show/Hide
C13H8F2N2O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0468521
4-(2,4-difluorophenoxy)furo[2,3-d]pyrimidine
   Show/Hide
C12H6F2N2O2
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0469035
4-(4-chlorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H8ClN3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0481301
4-(4-methoxyphenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H11N3O2
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0481303
4-(2,4-difluorophenoxy)-6-methoxyquinazoline
   Show/Hide
C15H10F2N2O2
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0487166
4-(3-fluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H8FN3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0487271
4-[(4-fluorophenyl)methyl]-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H10FN3
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0487272
4-(2,4-difluorophenoxy)pyrimidine
   Show/Hide
C10H6F2N2O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0497320
4-(2-fluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H8FN3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0506655
4-(2,4-dimethylphenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C14H13N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0506656
4-(2,4-difluorophenoxy)-7-methylpyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H9F2N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0506657
4-(2,4-difluorophenoxy)furo[3,2-d]pyrimidine
   Show/Hide
C12H6F2N2O2
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0541047
Type I progenitor, 4
   Show/Hide
C12H8N4O3
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0546439
4-(7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)benzonitrile
   Show/Hide
C13H8N4O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0546440
4-(2,4-difluorophenoxy)-5H-pyrrolo[3,2-d]pyrimidine
   Show/Hide
C12H7F2N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0547771
4-(2-methylphenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H11N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0547772
N-(4-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
   Show/Hide
C12H9FN4
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0548566
4-(2,4,6-trifluorophenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C12H6F3N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0556787
4-(4-methylphenoxy)-7H-pyrrolo[2,3-d]pyrimidine
   Show/Hide
C13H11N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0556792
4-(2,4-difluorophenoxy)quinazoline
   Show/Hide
C14H8F2N2O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0375197
3-N-propyl-5-(trifluoromethyl)benzene-1,3-diamine
   Show/Hide
C10H13F3N2
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0492520
N-[3-(propylamino)-5-(trifluoromethyl)phenyl]pyridine-2-carboxamide
   Show/Hide
C16H16F3N3O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0523042
2,6-difluoro-N-[3-[methyl(propyl)amino]-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C18H17F5N2O
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0524146
2,6-difluoro-N-[3-propoxy-5-(trifluoromethyl)phenyl]benzamide
   Show/Hide
C17H14F5NO2
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS
CP0537541
N-[3-(dipropylamino)-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
   Show/Hide
C18H21F3N2OS
 1
1
IC50 > 32000 nM
   TI
   LI
   LO
   TS