General Information of the Compound
Compound ID
CP0851507
Compound Name
Voacanginol
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Structure
Formula
C21H28N2O2
Molecular Weight
340.467
Canonical SMILES
CC[C@H]1C[C@H]2CN3CCc4c([nH]c5ccc(OC)cc45)[C@](CO)(C2)[C@H]13
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InChI
InChI=1S/C21H28N2O2/c1-3-14-8-13-10-21(12-24)19-16(6-7-23(11-13)20(14)21)17-9-15(25-2)4-5-18(17)22-19/h4-5,9,13-14,20,22,24H,3,6-8,10-12H2,1-2H3/t13-,14+,20+,21-/m1/s1
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InChIKey
JKVHRIYIUCRJFF-VKTIVEEGSA-N
Physicochemical Property
logP
3.0831
Rotatable Bonds
3
Heavy Atom Count
25
Polar Areas
48.49
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 12444907
ChEMBL ID
CHEMBL3325768
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02149, Transient receptor potential cation channel subfamily A member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  1
1
EC50 = 42000 nM
   TI
   LI
   LO
   TS
Protein ID: PT06117, Transient receptor potential cation channel subfamily M member 8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  1
1
IC50 = 19000 nM
   TI
   LI
   LO
   TS