General Information of the Compound
Compound ID
CP0278518
Compound Name
11H-dibenzo[b,e]azepine
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Synonyms
11H-Dibenz[b,e]azepine
11H-benzo[c][1]benzazepine
11H-dibenzo[b,e]azepine
256-86-0
CHEMBL1085101
CTK1A3708
DTXSID00446803
GTPL6473
Homoacridan
IDWNSAXOQLJYOF-UHFFFAOYSA-N
MORPHANTHRIDINE
SCHEMBL1150250
morphanthridine
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Structure
Formula
C14H11N
Molecular Weight
193.249
Canonical SMILES
C1c2ccccc2C=Nc2ccccc12
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InChI
InChI=1S/C14H11N/c1-2-7-13-10-15-14-8-4-3-6-12(14)9-11(13)5-1/h1-8,10H,9H2
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InChIKey
IDWNSAXOQLJYOF-UHFFFAOYSA-N
Physicochemical Property
logP
3.3414
Rotatable Bonds
0
Heavy Atom Count
15
Polar Areas
12.36
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Complexity
15

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10878016
SID: 15923582
ChEMBL ID
CHEMBL1085101
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02149, Transient receptor potential cation channel subfamily A member 1
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 3.02 nM
Clinical Information about the Compound
Drug 1 ( morphanthridine )
Drug Name morphanthridine
Target(s)
Transformation-sensitive protein p120 (TRPA1)
 Target Info 
Activator