Brief Information of the Compound and Protein
Compound Name
methyl benzo[b][1,4]benzoxazepine-10-carboxylate
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PubChem ID
CID: 42609882
SID: 81044709
Canonical SMILES
COC(=O)c1cccc2C=Nc3ccccc3Oc12
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Compound Formula C15H11NO3
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily A member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
O75762
Gene Name
TRPA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000058 T-REx-293 Homo sapiens (Human)  5
1
EC50 = 0.05 nM
   TI
   LI
   LO
   TS
2
EC50 = 7.413 nM
   TI
   LI
   LO
   TS
3
EC50 = 23.99 nM
   TI
   LI
   LO
   TS
4
EC50 = 83.18 nM
   TI
   LI
   LO
   TS
5
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.06026 nM