| Compound ID |
Compound Name |
Compound Formula |
|
CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C12H16N6O4
|
4
|
| 1 |
EC50 = 78 nM
|
|
|
| 2 |
EC50 = 10400 nM
|
|
|
| 3 |
Ki = 169 nM
|
|
|
| 4 |
Ki = 3200 nM
|
|
|
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CP0432769
|
[(2S,3S,4R,5R)-4-hydroxy-2-(hydroxymethyl)-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]oxolan-3-yl]urea
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|
C18H20IN7O4
|
5
|
| 1 |
EC50 = 180 nM
|
|
|
| 2 |
Ki = 220 nM
|
|
|
| 3 |
Ki = 470 nM
|
|
|
| 4 |
Ki > 10000 nM
|
|
|
| 5 |
Ki > 100000 nM
|
|
|
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CP0001102
|
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
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|
C10H13N5O4
|
1
|
| 1 |
EC50 = 1040 nM
|
|
|
|
CP0409614
|
4-Amino-2-(6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3-ol
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|
C15H22N6O3
|
2
|
| 1 |
Ki = 0.19 nM
|
|
|
| 2 |
Ki = 0.54 nM
|
|
|
|
CP0377319
|
(2R,3R,4S,5S)-4-Amino-5-hydroxymethyl-2-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-3-ol
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|
C17H19IN6O3
|
2
|
| 1 |
Ki = 0.87 nM
|
|
|
| 2 |
Ki = 32 nM
|
|
|
|
CP0395496
|
5-[6-(4-Amino-3-iodo-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid methylamide
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|
C18H20IN7O4
|
2
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 2.1 nM
|
|
|
|
CP0295042
|
4-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-2,3-dihydroxy-bicyclo[3.1.0]hexane-1-carboxylic acid methylamide
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|
C20H20ClIN6O3
|
2
|
| 1 |
Ki = 1.6 nM
|
|
|
| 2 |
Ki = 9.9 nM
|
|
|
|
CP0460291
|
4-Amino-5-[2-chloro-6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
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|
C18H19ClIN7O2
|
2
|
| 1 |
Ki = 2.3 nM
|
|
|
| 2 |
Ki = 4.6 nM
|
|
|
|
CP0017043
|
(2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C18H18ClIN6O4
|
2
|
| 1 |
Ki = 4.3 nM
|
|
|
| 2 |
Ki = 20.1 nM
|
|
|
|
CP0183628
|
(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (2-amino-ethyl)-amide
Show/Hide
|
C12H17N7O4
|
2
|
| 1 |
Ki = 9.6 nM
|
|
|
| 2 |
Ki > 100000 nM
|
|
|
|
CP0855218
|
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(azidomethyl)-tetrahydrothiophene-3,4-diol
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|
C16H15IN8O2S
|
2
|
| 1 |
Ki = 22 nM
|
|
|
| 2 |
Ki = 230 nM
|
|
|
|
CP0426831
|
2-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]guanidine
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|
C11H16N8O3
|
2
|
| 1 |
Ki = 33.3 nM
|
|
|
| 2 |
Ki = 130 nM
|
|
|
|
CP0405061
|
4-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
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|
C22H17N3O2
|
2
|
| 1 |
Ki = 61.7 nM
|
|
|
| 2 |
Ki = 1690 nM
|
|
|
|
CP0467103
|
3'-amino-3'-deoxyadenosine
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|
C10H14N6O3
|
2
|
| 1 |
Ki = 75 nM
|
|
|
| 2 |
Ki = 442 nM
|
|
|
|
CP0104008
|
N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetamide
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|
C21H28N6O4
|
2
|
| 1 |
Ki = 110 nM
|
|
|
| 2 |
Ki = 20100 nM
|
|
|
|
CP0498526
|
(2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3-(aminomethyl)-4-hydroxy-N-methyl-tetrahydrofuran-2-carboxamide
Show/Hide
|
C19H22IN7O3
|
5
|
| 1 |
Ki = 110 nM
|
|
|
| 2 |
Ki = 120 nM
|
|
|
| 3 |
Ki = 137 nM
|
|
|
| 4 |
Ki = 185 nM
|
|
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| 5 |
Ki = 570 nM
|
|
|
|
CP0424918
|
3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydroxy-tetrahydro-furan-2-carboxylic acid methyl amide
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|
C18H18IN9O3
|
5
|
| 1 |
Ki = 140 nM
|
|
|
| 2 |
Ki = 186 nM
|
|
|
| 3 |
Ki = 1370 nM
|
|
|
| 4 |
Ki = 2000 nM
|
|
|
| 5 |
Ki = 2260 nM
|
|
|
|
CP0500542
|
[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]urea
Show/Hide
|
C18H19ClIN7O4
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0044275
|
9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine
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|
C13H8ClN5O
|
2
|
| 1 |
Ki = 253 nM
|
|
|
| 2 |
Ki = 3260 nM
|
|
|
|
CP0430608
|
2'-AMINO-2'-DEOXYADENOSINE
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|
C10H14N6O3
|
1
|
| 1 |
Ki = 301 nM
|
|
|
|
CP0424917
|
(2S,3S,4R,5R)-5-(6-(5-chloro-2-methoxybenzylamino)-9H-purin-9-yl)-3-(aminomethyl)-4-hydroxy-N-methyl-tetrahydrofuran-2-carboxamide
Show/Hide
|
C20H24ClN7O4
|
5
|
| 1 |
Ki = 390 nM
|
|
|
| 2 |
Ki = 557 nM
|
|
|
| 3 |
Ki = 592 nM
|
|
|
| 4 |
Ki = 850 nM
|
|
|
| 5 |
Ki = 7200 nM
|
|
|
|
CP0257633
|
(2R,3S,4R,5R)-2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C10H14N6O3
|
1
|
| 1 |
Ki = 425 nM
|
|
|
|
CP0378381
|
(2R,3R,4S,5S)-2-(6-(3-iodobenzylamino)-9H-purin-9-yl)-4-(aminomethyl)-5-(hydroxymethyl)-tetrahydrofuran-3-ol
Show/Hide
|
C18H21IN6O3
|
6
|
| 1 |
Ki = 610 nM
|
|
|
| 2 |
Ki = 850 nM
|
|
|
| 3 |
Ki = 9500 nM
|
|
|
| 4 |
Ki = 10000 nM
|
|
|
| 5 |
Ki > 10000 nM
|
|
|
| 6 |
Ki = 10700 nM
|
|
|
|
CP0155498
|
2-CI Adenosine
Show/Hide
|
C10H12ClN5O4
|
2
|
| 1 |
Ki = 650 nM
|
|
|
| 2 |
Ki = 11600 nM
|
|
|
|
CP0424919
|
N-[[(2S,3S,4R,5R)-4-hydroxy-2-(hydroxymethyl)-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]oxolan-3-yl]methyl]acetamide
Show/Hide
|
C20H23IN6O4
|
3
|
| 1 |
Ki = 700 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
| 3 |
Ki > 10000 nM
|
|
|
|
CP0432768
|
(2R,3R,4S,5S)-2-(6-(5-chloro-2-methoxybenzylamino)-9H-purin-9-yl)-4-(aminomethyl)-5-(hydroxymethyl)-tetrahydrofuran-3-ol
Show/Hide
|
C19H23ClN6O4
|
5
|
| 1 |
Ki = 709 nM
|
|
|
| 2 |
Ki = 2000 nM
|
|
|
| 3 |
Ki = 9800 nM
|
|
|
| 4 |
Ki > 10000 nM
|
|
|
| 5 |
Ki = 13800 nM
|
|
|
|
CP0453290
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carbohydrazide
Show/Hide
|
C10H13N7O4
|
2
|
| 1 |
Ki = 1500 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0456519
|
3-ureido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydroxy-tetrahydro-furan-2-carboxylic acid methyl amide
Show/Hide
|
C19H21IN8O4
|
1
|
| 1 |
Ki = 2700 nM
|
|
|
