Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-azido-5-(6-(3-iodobenzylamino)purin-9-yl)-4-hydroxy-tetrahydro-furan-2-carboxylic acid methyl amide
    Show/Hide
 PubChem ID
CID: 44410761
Canonical SMILES
CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1N=[N+]=[N-])n1cnc2c(NCc3cccc(I)c3)ncnc12
    Show/Hide
Compound Formula C18H18IN9O3
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  5
1
Ki = 140 nM
   TI
   LI
   LO
   TS
2
Ki = 186 nM
   TI
   LI
   LO
   TS
3
Ki = 1370 nM
   TI
   LI
   LO
   TS
4
Ki = 2000 nM
   TI
   LI
   LO
   TS
5
Ki = 2260 nM
   TI
   LI
   LO
   TS