Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide
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 PubChem ID
CID: 10247610
SID: 15250688
Canonical SMILES
COc1ccc(cc1)C(=O)Nc1nc(cc2ccccc12)-c1ccccn1
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Compound Formula C22H17N3O2
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 17 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  2
1
Ki = 61.7 nM
   TI
   LI
   LO
   TS
2
Ki = 1690 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 17 nM
   TI
   LI
   LO
   TS