Brief Information of the Cell Line and Protein
Cell Line ID: CL000044 , CV-1
Synonyms
Cv-1
CV 1
CV-1.K
CV1
Category Finite cell line
Organism
Chlorocebus aethiops (Green monkey)
Cellosaurus ID
CVCL_0229
Protein ID: PT03152 , Retinoic acid receptor RXR-alpha
Gene Name RXRA
Organism Mus musculus, Mouse
Protein Classification Transcription factor
Uniprot ID P28700
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000044  Protein ID: PT03152
 
Compound ID Compound Name Compound Formula
CP0126004
(2E,4E,6E,8Z)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid
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C20H28O2
 1
1
EC50 = 27 nM
   TI
   LI
   LO
   TS
CP0004259
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid
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C24H28O2
 1
1
EC50 = 40 nM
   TI
   LI
   LO
   TS
CP0043939
(2E,4Z,6Z)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid
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C20H22O2
 1
1
EC50 = 118 nM
   TI
   LI
   LO
   TS
CP0042977
9-cis retinoic acid
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C20H28O2
 1
1
EC50 = 200 nM
   TI
   LI
   LO
   TS
CP0082294
(2E,4Z,6Z)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid
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C21H30O2
 1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
CP0153500
(E)-3-[5'-(Adamant-1-yl)-2-chloro-4'-hydroxy-2'-methylbiphenyl-4-yl]acrylic acid
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C26H27ClO3
 1
1
EC50 = 576 nM
   TI
   LI
   LO
   TS
CP0084055
(E)-3-[5'-(Adamant-1-yl)-2-chloro-4'-[(2-methoxyethoxy)methoxy]-2'-methylbiphenyl-4-yl]acrylic acid
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C30H35ClO5
 1
1
EC50 = 600 nM
   TI
   LI
   LO
   TS
CP0084902
6-[5-(Adamant-1-yl)-4-[(2-methoxyethoxy)methoxy]-2-methylphenyl]-5-chloro-2-naphthoic acid
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C32H35ClO5
 1
1
EC50 = 667 nM
   TI
   LI
   LO
   TS
CP0070442
2-[5'-(Adamant-1-yl)-2-chloro-4'-[(2-methoxyethoxy)methoxy]-2'-methylbiphenyl-4-yl]acetic Acid
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C29H35ClO5
 1
1
EC50 = 1137 nM
   TI
   LI
   LO
   TS
CP0040160
9-cis-retinoic acid (9cRA)
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C20H28O2
 1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS
CP0098128
(2E,4E,6E)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid
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C20H22O2
 1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS
CP0101102
(2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid
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C21H30O2
 1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS
CP0162300
(2Z,4E,6E)-8-[3,4-Dihydro-2H-naphthalen-(1E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid
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C20H22O2
 1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS
CP0216905
(2Z,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid
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C21H30O2
 1
1
EC50 > 2000 nM
   TI
   LI
   LO
   TS