N'-(5-chloro-6-methyl-2-pyridin-2-ylpyrimidin-4-yl)-N-[5-(trifluoromethyl)pyridin-2-yl]ethane-1,2-diamine

5-(2-fluorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine

SID104222625

SID49644133

N-(5-Chloro-6-methyl-2-pyridin-2-yl-pyrimidin-4-yl)-N'-(4-trifluoromethyl-pyridin-2-yl)-ethane-1,2-diamine

SID49644899

5-methoxy-4-phenoxy-2-(2-pyridinyl)pyrimidine

4-((2-(2,6-dimorpholinopyrimidin-4-yl)hydrazono)methyl)benzene-1,3-diol

5-Benzyl-4,6-dichloro-2-pyridin-2-yl-pyrimidine

1-(5-Methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-3-phenyl-urea

5-methoxy-2-(pyridin-2-yl)pyrimidine

5-methoxy-N-(3-phenylpropyl)-2-(pyridin-2-yl)pyrimidin-4-amine

Isopropyl-(5-methoxy-2-phenyl-pyrimidin-4-yl)-amine

5-(2-Fluoro-benzyl)-6-morpholin-4-yl-2-(5-morpholin-4-yl-pyridin-2-yl)-pyrimidin-4-ylamine

5-(4-Methoxy-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

6-Chloro-2-pyridin-2-yl-pyrimidin-4-ylamine

4,4'-(6-(2-benzylidenehydrazinyl)pyrimidine-2,4-diyl)dimorpholine

2-((4-(2,6-dimorpholinopyrimidin-4-yl)piperazin-1-yl)methyl)phenol

[5-(2-Fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-methyl-amine

4-chloro-5-methoxy-2,2'-bipyrimidine

sodium 2-(1-(2,6-dimorpholinopyrimidin-4-yl)-1H-1,2,4-triazol-3-yl)phenolate

[5-(2-Fluoro-benzyl)-2-pyridin-3-yl-pyrimidin-4-yl]-isopropyl-amine

N-(5-Methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-acetamide

Isopropyl-[5-methoxy-2-(1H-pyrrol-2-yl)pyrimidin-4-yl]-amine

Isopropyl-[5-methoxy-2-(1H-pyrazol-5-yl)pyrimidin-4-yl]-amine

4,6-Dichloro-5-(2-fluoro-benzyl)-2-(5-fiuoro-pyridin-2-yl)-pyrimidine

6-Chloro-5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-ylamine

2-((2-(2-methyl-6-morpholinopyrimidin-4-yl)hydrazono)methyl)phenol

2-(2-(2,6-dimorpholinopyrimidin-4-yloxy)ethyl)phenol

2-(2-(2,6-dimorpholinopyrimidin-4-ylamino)ethyl)phenol

2-(2-(4,6-dimorpholino-1,3,5-triazin-2-yloxy)ethyl)phenol

4-[5-Benzyl-6-(morpholin-4-yl)-2-(pyridin-2-yl)-pyrimidin-4-yl]morpholine

Isopropyl-(5-methoxy-2-pyridin-4-yl-pyrimidin-4-yl)-amine

5-Methoxy-4-(4-methyl-piperazin-1-yl)-2-pyridin-2-yl-pyrimidine

5-Benzyl-6-chloro-2-pyridin-2-yl-pyrimidin-4-ylamine

Benzyl-[5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-methyl-amine

Diethyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-amine

1-(5-Methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-3-methyl-urea

(5-Isopropoxy-2-pyridin-2-yl-pyrimidin-4-yl)-isopropyl-amine

5-(2-Fluoro-benzyl)-2-pyridin-3-yl-pyrimidin-4-ol

2-((2-(4,6-dimorpholino-1,3,5-triazin-2-yl)hydrazono)methyl)phenol

Isopropyl-(5-methoxy-2-pyrazin-2-yl-pyrimidin-4-yl)-amine

4-Chloro-5-(2-fluoro-benzyl)-2-pyridin-3-yl-pyrimidine

N-isopropyl-5-methoxy-2,2'-bipyrimidin-4-amine

5-methoxy-2,2'-bipyrimidin-4-ol

5-Benzyl-2-pyridin-2-yl-pyrimidine-4,6-diol

5-(2-Fluoro-benzyl)-2-(6-trifluoromethyl-pyridin-2-yl)-pyrimidine-4,6-diamine

5-(2-Ethoxy-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

5-(2-Fluoro-benzyl)-N,N'-diisopropyl-2-pyridin-2-yl-pyrimidine-4,6-di amine

5-(2-Fluoro-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diol

5-Methoxy-2-pyridin-2-yl-pyrimidin-4-ylamine

Isopropyl-(5-methoxy-2-pyridin-3-yl-pyrimidin-4-yl)-amine

Isopropyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-methyl-amine

Isobutyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-methyl-amine

5-(2-Fluoro-benzyl)-2-(6-methyl-pyridin-2-yl)-pyrimidine-4,6-diamine

4,6-Dichloro-5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidine

1-Isopropyl-3-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-urea

4,6-dimorpholino-1,3,5-triazin-2-amine

5-Methoxy-4-(piperidin-1-yl)-2-(pyridin-2-yl)pyrimidine

5-(2-Methoxy-5-methyl-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

4-((2-(4,6-dimorpholino-1,3,5-triazin-2-yl)hydrazono)methyl)benzene-1,3-diol

Cyclohexylmethyl-[5-(2-fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-amine

4-{5-[(2-Fluorophenyl)methyl]-6-(morpholin-4-yl)-2-(pyridin-2-yl)pyrimidin-4-yl}morpholine

N'-(2,6-dimorpholinopyrimidin-4-yl)-2-hydroxybenzohydrazide

2-(pyridin-2-yl)pyrimidine-4,6-diol

4-((2-(4-methyl-6-morpholino-1,3,5-triazin-2-yl)hydrazono)methyl)benzene-1,3-diol

[1-(4-Fluorophenyl)-2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)ethyl]thiophen-2-ylmethylamine

Benzyl[1-(4-fluorophenyl)-2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)ethyl]amine

(2-Aminomethyl-5-methoxy-pyrimidin-4-yl)-isopropyl-amine

4-[(4-methyl-6-morpholin-4-yl-[1,3,5]triazin-2-yl)-hydrazonomethyl]-benzene-1,3-diol

2-[2-(4,6-di-morpholin-4-yl-[1,3,5]triazin-2-yloxy)-ethyl]-phenol

7-Morpholin-4-ylmethyl-8-(3,4,5-trimethoxybenzyloxy)-quinoline

5,7-Bis-morpholin-4-ylmethyl-quinolin-8-ol

(4-{2-(4-Fluorophenyl)-2-[(pyridin-2-ylmethyl)amino]ethyl}piperazin-1-yl)pyridin-2-yl-methanone

(4-Methoxybenzyl)(1-phenyl-2-piperidin-1-yl-ethyl)amine

1-{1-Phenyl-2-[4-(piperidin-1-yl)piperidin-1-yl]ethyl}-4-(propan-2-yl)piperazine

1-(2-(4-cyclohexylpiperidin-1-yl)-1-phenylethyl)-4-(2-methoxyethyl)piperazine

[1-(4-Fluorophenyl)-2-(4-pyridin-2-yl-piperazin-1-yl)ethyl]pyridin-2-ylmethylamine

{4-[2-(4-Fluorophenyl)-2-(2-methoxyethylamino)ethyl]piperazin-1-yl}(tetrahydrofuran-2-yl)methanone

1-(4-Fluorophenyl)-2-(2,3,5,6-tetrahydro-[1,2']-bipyrazinyl-4-yl)ethylamine

[4-(2-[1,4']Bipiperidinyl-1'-yl-1-phenylethyl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone

1-(2-methoxyethyl)-4-(2-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)-1-phenylethyl)piperazine

(4-{2-(4-Fluorophenyl)-2-[(pyridin-2-ylmethyl)-amino]-ethyl}-piperazin-1-yl)(tetrahydro-furan-2-yl)methanone

[1-(4-Fluorophenyl)-2-(4-phenylpiperazin-1-yl)ethyl]pyridin-2-ylmethylamine

[2-(4-Benzenesulfonyl-piperazin-1-yl)-1-(4-fluorophenyl)ethyl]pyridin-2-ylmethylamine

(4-{2-(4-Fluorophenyl)-2-[(thiophen-2-ylmethyl)amino]ethyl}piperazin-1-yl)(tetrahydrofuran-2-yl)methanone

{4-[2-Amino-2-(4-fluorophenyl)ethyl]piperazin-1-yl}(tetrahydrofuran-2-yl)methanone

1-Cyclopentyl-4-{1-phenyl-2-[4-(piperidin-1-yl)piperidin-1-yl]ethyl}piperazine

1-(2-(4-(2-methoxyethyl)piperazin-1-yl)-2-phenylethyl)-N-phenylpiperidin-4-amine

ethyl 1-(2-(4-(2-methoxyethyl)piperazin-1-yl)-2-phenylethyl)piperidine-4-carboxylate

[1-(2-Fluorophenyl)-2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)ethyl]pyridin-2-ylmethylamine

1'[2-Phenyl-2-(4-pyridin-2-yl-piperazin-1-yl)ethyl][1,4']bipiperidinyl

1'-(2-(3-chlorophenyl)-2-(4-(2-methoxyethyl)piperazin-1-yl)ethyl)-1,4'-bipiperidine

1'-(2-(2-chlorophenyl)-2-(4-(2-methoxyethyl)piperazin-1-yl)ethyl)-1,4'-bipiperidine

1'-(2-(4-ethoxyphenyl)-2-(4-(2-methoxyethyl)piperazin-1-yl)ethyl)-1,4'-bipiperidine

1'-(2-(4-(2-(1H-imidazol-1-yl)ethyl)piperazin-1-yl)-2-phenylethyl)-1,4'-bipiperidine

1-Butyl-4-{1-phenyl-2-[4-(piperidin-1-yl)piperidin-1-yl]ethyl}piperazine

N-(1-(2-(4-(2-methoxyethyl)piperazin-1-yl)-2-phenylethyl)piperidin-4-yl)benzamide

1'-(2-(4-isopropoxyphenyl)-2-(4-(2-methoxyethyl)piperazin-1-yl)ethyl)-1,4'-bipiperidine

[1-(3-Fluorophenyl)-2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)ethyl]pyridin-2-ylmethylamine

4-(2-[1,4']bipiperidinyl-1'-yl-1-phenylethyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl

1-(2-methoxyethyl)-4-(1-phenyl-2-(4-phenylpiperazin-1-yl)ethyl)piperazine

[4-(2-Benzylamino-2-phenylethyl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone

4-{2-[4-(2-Methoxyethyl)piperazin-1-yl]-2-phenylethyl}morpholine

N-cyclohexyl-1-(2-(4-(2-methoxyethyl)piperazin-1-yl)-2-phenylethyl)piperidine-4-carboxamide

1'-(2-(4-chlorophenyl)-2-(4-(2-methoxyethyl)piperazin-1-yl)ethyl)-1,4'-bipiperidine

1-(4-fluorophenyl)-N-(2-methoxyethyl)-2-(4-(pyrazin-2-yl)piperazin-1-yl)ethanamine

{4-[2-Benzylamino-2-(4-fluorophenyl)ethyl]piperazin-1-yl}(tetrahydrofuran-2-yl)methanone

2-(4-(2-(1,4'-bipiperidin-1'-yl)-1-phenylethyl)piperazin-1-yl)-N,N-diethylethanamine

[1-(4-Chlorophenyl)-2-(2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)ethyl]pyridin-2-ylmethylamine

Pyridin-2-ylmethyl-[1-pyridin-4-yl-2-(2,3,5,6-tetrahydro[1,2']bipyrazinyl-4-yl)ethyl]amine

[1-Phenyl-2-(2,3,5,6-tetrahydro[1,2']bipyrazinyl-4-yl)ethyl]pyridin-2-ylmethylamine

1'-{2-[4-(2-Methoxyethyl)piperidin-1-yl]-2-phenylethyl}[1,4']bipiperidinyl

1-(4-{2-(4-Fluorophenyl)-2[(pyridin-2-ylmethyl)amino]ethyl}piperazin-1-yl)ethanone

5-chloranyl-7-[pyridin-3-yl-(pyridin-2-ylamino)methyl]quinolin-8-ol

5-chloro-7-(morpholin-4-ylmethyl)quinolin-8-ol

5-chloranyl-7-[piperidin-1-yl(pyridin-2-yl)methyl]quinolin-8-ol

3,4,5-trimethoxybenzoic acid [5-chloro-7-(4-morpholinylmethyl)-8-quinolinyl] ester

7-[4-morpholinyl(2-pyridinyl)methyl]-8-quinolinol

MLS000770989

7-[(4-methoxyphenyl)-morpholin-4-ylmethyl]quinolin-8-ol

7-{[4-(2-Hydroxy-ethyl)-piperazin-1-pyridin-2-yl-methyl}-quinolin-8-ol

Furan-2-carboxylic acid 5-chloro-7-morpholin-4-ylmethyl-quinolin-8-yl ester

7-((1-benzyl-1H-imidazol-2-yl)(morpholino)methyl)quinolin-8-ol

5-Chloro-7-[(2,6-dimethyl-morpholin-4-yl-pyridin-2-yl-methyl]-quinolin-8-ol

7-(Morpholin-4-yl-pyrazin-2-yl-methyl)-quinolin-8-ol

7-Morpholin-4-yl-methyl-quinolin-8-ol

5-Chloro-7-[(4-chloro-phenyl)-morpholin-4-yl-methyl]-quinolin-8-ol

7-[(Benzyl-methyl-amino)-pyridin-4-yl-methyl]-quinolin-8-ol

7-[(4-Fluoro-phenyl)-morpholin-4-ylmethyl-quinolin-8-ol

7-(Morpholin-4-yl-pyridin-4-yl-methyl)-quinolin-8-ol

7-[(6-Methoxy-pyridin-3-yl)-morpholin-4-yl-methyl]-quinolin-8-ol

4-[(8-Hydroxy-quinolin-7-yl)-morpholin-4-yl-methyl]-benzamide

7-(Morpholin-4-yl-o-tolyl-methyl)-quinolin-8-ol

7-[(4-Benzyl-piperidin-1-yl)-pyridin-2-yl-methyl]quinolin-8-ol

7-[(2,6-Dimethyl-morpholin-4-yl)-(4-fluoro-phenyl)-methyl]-quinolin-8-ol

7-[(4-Benzyl-piperazin-1-yl)-pyridin-2-yl-methyl]quinolin-8-ol

7-[(4-Chloro-phenyl)-morpholin-4-yl-methyl]-quinolin-8-ol

7-(Morpholin-4-yl-p-tolyl-methyl)-quinolin-8-ol

DNDI1417613

7-[Pyridin-2-yl-(4-pyridin-2-yl-piperazin-1-yl)-methyl]-quinolin-8-ol

4-[(8-Hydroxy-quinolin-7-yl)-morpholin-4-yl-methyl]-benzonitrile

7-[(2,6-Dimethyl-morpholin-4-yl)-pyridin-4-yl-methyl]-quinolin-8-ol

7-[(4-Methyl-piperazin-1-yl)-pyridin-2-yl-methyl]-quinolin-8-ol

4-[(8-Hydroxy-quinolin-7-yl)-pyridin-2-yl-methyl]-piperazine-1-carboxylic acid ethyl ester

7-(Morpholin-4-yl-pyridin-3-yl-methyl)-quinolin-8-ol

7-[(2-Methoxy-phenyl)-morpholin-4-yl-methyl]-quinolin-8-ol

5-Chloro-7-(morpholin-4-yl-pyridin-2-yl-methyl)-quinolin-8-ol

7-{[4-(2-Fluoro-phenyl)-piperidin-1-yl]-pyridin-2-yl-methyl}-quinolin-8-ol

7-(Piperidin-1-yl-pyridin-2-yl-methyl)-quinolin-8-ol

5-Chloro-7-(morpholin-4-yl-thiophen-2-yl-methyl)-quinolin-8-ol

7-(Morpholin-4-yl-thiophen-2-yl-methyl)-quinolin-8-ol

7-(Benzylamino-pyridin-4-yl-methyl)-quinolin-8-ol

US10584134, Example 2-1

5-(2,4-dichlorobenzyl)-2-(2-pyridinyl)-4,6-pyrimidinediamine

US10584134, Example 2-11

US10584134, Example 2-4

5-methoxy-N,N-dimethyl-2-pyridin-2-ylpyrimidin-4-amine

SID49666601

N-Isopropyl-2-pyridin-2-yl-pyrimidine-4,6-diamine

5-(2,5-Difluoro-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

5-(3-Chloro-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

N-ethyl-5-methoxy-N-methyl-2-(pyridin-2-yl)pyrimidin-4-amine

Cyclohexylmethyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-amine

(4,6-Dimorpholin-4-yl-[1,3,5]triazin-2-yl)-(2-methyl-quinolin-6-yl)-amine

5-(2,4-Dimethoxy-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

5-(3-Fluoro-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine

Butyl-(5-methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-amine

2-[(2,6-Dimorpholin-4-yl-pyrimidin-4-yl)-hydrazonomethyl]-phenol

N-(5-Methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-benzenesulfonamide

5-(2-Fluoro-benzyl)-2-(5-methoxy-pyridin-2-yl)-pyrimidine-4,6-diamine

5-(2-Methyl-benzyl)-2-pyridin-2-yl-pyrimidine-4,6-diamine