General Information of the Compound
Compound ID
CP0876843
Compound Name
1-(5-Methoxy-2-pyridin-2-yl-pyrimidin-4-yl)-3-phenyl-urea
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Structure
Formula
C17H15N5O2
Molecular Weight
321.34
Canonical SMILES
COc1cnc(-c2ccccn2)nc1NC(=O)Nc1ccccc1
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InChI
InChI=1S/C17H15N5O2/c1-24-14-11-19-15(13-9-5-6-10-18-13)21-16(14)22-17(23)20-12-7-3-2-4-8-12/h2-11H,1H3,(H2,19,20,21,22,23)
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InChIKey
NJQNSYVWLLQRGO-UHFFFAOYSA-N
Physicochemical Property
logP
3.1912
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
89.03
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 51042242
SID: 117702862
ChEMBL ID
CHEMBL4532107
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06765, Hepcidin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 > 50000 nM
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