General Information of the Compound
Compound ID
CP0930924
Compound Name
4-[5-(2-Fluoro-benzyl)-2-pyridin-2-yl-pyrimidin-4-yl]-morpholine
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Structure
Formula
C20H19FN4O
Molecular Weight
350.397
Canonical SMILES
Fc1ccccc1Cc1cnc(-c2ccccn2)nc1N1CCOCC1
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InChI
InChI=1S/C20H19FN4O/c21-17-6-2-1-5-15(17)13-16-14-23-19(18-7-3-4-8-22-18)24-20(16)25-9-11-26-12-10-25/h1-8,14H,9-13H2
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InChIKey
JRGUXFPPMCIQBH-UHFFFAOYSA-N
Physicochemical Property
logP
3.1051
Rotatable Bonds
4
Heavy Atom Count
26
Polar Areas
51.14
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 51040720
SID: 117701290
ChEMBL ID
CHEMBL4472028
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06765, Hepcidin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000031 MDCK Canis lupus familiaris (Dog)  1
1
IC50 < 50000 nM
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