| Compound ID |
Compound Name |
Compound Formula |
|
CP0233685
|
1-[[6-[(2-methoxy-4-propylphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H33NO4
|
4
|
| 1 |
Activity = 25 nM
|
|
|
| 2 |
EC50 = 0.027 nM
|
|
|
| 3 |
EC50 = 1 nM
|
|
|
| 4 |
Ki = 0.626 nM
|
|
|
|
CP0414090
|
1-[[6-[(2-methoxy-4-propylphenyl)methoxy]-1,5-dimethyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO4
|
2
|
| 1 |
EC50 = 0.072 nM
|
|
|
| 2 |
EC50 = 1.2 nM
|
|
|
|
CP0517777
|
1-[[6-[(2-methoxy-6-propylpyridin-3-yl)methoxy]-1,5-dimethyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H34N2O4
|
2
|
| 1 |
EC50 = 0.19 nM
|
|
|
| 2 |
EC50 = 1.2 nM
|
|
|
|
CP0473592
|
1-[[6-[(2-methoxy-6-propylpyridin-3-yl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H32N2O4
|
1
|
| 1 |
EC50 = 0.58 nM
|
|
|
|
CP0543034
|
1-[[6-[(4-ethyl-2-methoxyphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H31NO4
|
1
|
| 1 |
EC50 = 0.58 nM
|
|
|
|
CP0419792
|
1-[[6-[[2-methoxy-4-(2-methylpropyl)phenyl]methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO4
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0271655
|
2-[6-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,2,4-oxadiazol-3-yl]-5-methyl-3,4-dihydro-1H-isoquinolin-2-yl]-N-[(2S)-1-hydroxypropan-2-yl]acetamide
Show/Hide
|
C27H31N5O4
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0402878
|
1-[[6-[(2-methoxy-4-methylphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H29NO4
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0058563
|
3-[2-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid
Show/Hide
|
C21H24ClN5O3S
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0517778
|
1-[[6-[2-(2,3-dihydro-1H-inden-1-yl)ethoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H31NO3
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0449330
|
[(2R)-2-amino-3-[[2,6-dimethyl-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]-2-methylpropyl] dihydrogen phosphate
Show/Hide
|
C24H34NO6P
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
|
CP0448339
|
[(2R)-2-amino-3-[[2-ethyl-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]-2-methylpropyl] dihydrogen phosphate
Show/Hide
|
C24H34NO6P
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0491425
|
US9181182, 47
Show/Hide
|
C26H34N4O3
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
|
CP0447370
|
1-[[6-[[2-fluoro-4-(2-methylpropyl)phenyl]methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H32FNO3
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0481914
|
[(2R)-2-amino-3-[[2-fluoro-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]-2-methylpropyl] dihydrogen phosphate
Show/Hide
|
C22H29FNO6P
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0484160
|
US9181182, 56
Show/Hide
|
C23H27BrN4O4
|
1
|
| 1 |
EC50 = 2.9 nM
|
|
|
|
CP0375200
|
[(2R)-2-amino-2-methyl-3-[[2-methyl-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]propyl] dihydrogen phosphate
Show/Hide
|
C23H32NO6P
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0447349
|
1-[[1-methyl-6-(3-phenylpropoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H29NO3
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0548860
|
1-[[6-[[3-methoxy-4-(2-methylpropyl)phenyl]methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO4
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0160244
|
5-[3-[2-(1,3-dihydroxypropan-2-yl)-5-methyl-3,4-dihydro-1H-isoquinolin-6-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C25H28N4O4
|
1
|
| 1 |
EC50 = 3.162 nM
|
|
|
|
CP0385905
|
3-[2-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid
Show/Hide
|
C22H24N6O3S
|
1
|
| 1 |
EC50 = 3.162 nM
|
|
|
|
CP0578230
|
US9181182, 51
Show/Hide
|
C23H27ClN4O4
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0567137
|
1-[[6-[(4-butyl-2-methoxyphenyl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO4
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0469575
|
3-[2-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid
Show/Hide
|
C20H22ClN5O3S
|
1
|
| 1 |
EC50 = 3.981 nM
|
|
|
|
CP0481915
|
[(2R)-2-amino-3-[[2-chloro-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]-2-methylpropyl] dihydrogen phosphate
Show/Hide
|
C22H29ClNO6P
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0534773
|
1-[[6-[[2-chloro-4-(2-methylpropyl)phenyl]methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H32ClNO3
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
|
CP0447351
|
1-[[1-methyl-6-[[4-(2-methylpropyl)phenyl]methoxy]-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H33NO3
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0385906
|
4-[2-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]butanoic acid
Show/Hide
|
C21H24ClN5O3S
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0385909
|
3-[2-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid
Show/Hide
|
C21H22N6O3S
|
1
|
| 1 |
EC50 = 5.012 nM
|
|
|
|
CP0435958
|
3-[6-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,2,4-oxadiazol-3-yl]-5-methyl-3,4-dihydro-1H-isoquinolin-2-yl]propanoic acid
Show/Hide
|
C25H26N4O4
|
2
|
| 1 |
EC50 = 5.012 nM
|
|
|
| 2 |
EC50 = 5.623 nM
|
|
|
|
CP0385910
|
4-[2-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]butanoic acid
Show/Hide
|
C22H24N6O3S
|
1
|
| 1 |
EC50 = 6.31 nM
|
|
|
|
CP0397845
|
[(2R)-2-amino-3-[[2,5-dimethyl-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]-2-methylpropyl] dihydrogen phosphate
Show/Hide
|
C24H34NO6P
|
1
|
| 1 |
EC50 = 6.5 nM
|
|
|
|
CP0519584
|
1-[[6-[[4-(2-hydroxy-2-methylpropyl)-2-methoxyphenyl]methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO5
|
1
|
| 1 |
EC50 = 6.6 nM
|
|
|
|
CP0418197
|
US9181182, 48
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
EC50 = 6.7 nM
|
|
|
|
CP0413430
|
US9181182, 34
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 6.8 nM
|
|
|
|
CP0428009
|
[(2R)-2-amino-2-methyl-3-[[4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]propyl] dihydrogen phosphate
Show/Hide
|
C22H30NO6P
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0418195
|
US9181182, 65
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
|
CP0467529
|
1-[[6-(2,3-dihydro-1H-inden-2-ylmethoxy)-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H29NO3
|
1
|
| 1 |
EC50 = 7.9 nM
|
|
|
|
CP0205171
|
5-[3-[2-(1,3-dihydroxypropan-2-yl)-3,4-dihydro-1H-isoquinolin-6-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
EC50 = 7.943 nM
|
|
|
|
CP0567138
|
1-[[1-methyl-6-[[2-methyl-4-(2-methylpropyl)phenyl]methoxy]-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO3
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0413428
|
US9181182, 50
Show/Hide
|
C23H27ClN4O4
|
1
|
| 1 |
EC50 = 17.9 nM
|
|
|
|
CP0419392
|
US9181182, 43
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0523054
|
[(2R)-2-amino-2-methyl-3-[[3-methyl-4-[4-(4-methylphenyl)butanoyl]phenyl]methoxy]propyl] dihydrogen phosphate
Show/Hide
|
C23H32NO6P
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0548859
|
1-[[1-methyl-6-(1,2,3,4-tetrahydronaphthalen-2-ylmethoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H31NO3
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0160245
|
5-[3-[7-(1,3-dihydroxypropan-2-yl)-4-methyl-6,8-dihydro-5H-1,7-naphthyridin-3-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C24H27N5O4
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0197254
|
5-[3-[3-(1,3-dihydroxypropan-2-yl)-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C25H28N4O4
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0224274
|
2-propan-2-yloxy-5-[3-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)-1,2,4-oxadiazol-5-yl]pyridine-3-carbonitrile
Show/Hide
|
C21H21N5O2
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0224275
|
5-[3-[4-(1,3-dihydroxypropan-2-yl)-3,5-dihydro-2H-1,4-benzoxazepin-9-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C24H26N4O5
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0275274
|
[(2S)-2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate
Show/Hide
|
C19H34NO5P
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0385903
|
3-[1-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3,5-dimethylpyrazol-4-yl]propanoic acid
Show/Hide
|
C19H21ClN4O3S
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0526512
|
US9181182, 55
Show/Hide
|
C23H28N4O5
|
1
|
| 1 |
EC50 = 31.6 nM
|
|
|
|
CP0578229
|
US9181182, 52
Show/Hide
|
C24H29ClN4O4
|
1
|
| 1 |
EC50 = 34.5 nM
|
|
|
|
CP0478864
|
US9181182, 54
Show/Hide
|
C25H31ClN4O4
|
1
|
| 1 |
EC50 = 43.8 nM
|
|
|
|
CP0500454
|
US9181182, 44
Show/Hide
|
C23H27IN4O4
|
1
|
| 1 |
EC50 = 48.1 nM
|
|
|
|
CP0452405
|
3-[1-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid
Show/Hide
|
C20H22ClN5O3S
|
1
|
| 1 |
EC50 = 50.12 nM
|
|
|
|
CP0519025
|
US9181182, 35
Show/Hide
|
C24H28N4O5
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0519587
|
1-[[1-methyl-6-(naphthalen-2-ylmethoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H27NO3
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0419818
|
1-[[6-[(4-methoxy-6-propylpyridin-3-yl)methoxy]-1-methyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H32N2O4
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0555692
|
5-[5-(3-methyl-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-2-yl)-1,3,4-thiadiazol-2-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C19H20N6OS
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0518992
|
US9181182, 46
Show/Hide
|
C23H29N5O4
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0447371
|
1-[[1-methyl-6-[2-(1,2,3,4-tetrahydronaphthalen-1-yl)ethoxy]-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H33NO3
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0385908
|
2-[2-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]acetic acid
Show/Hide
|
C21H22N6O3S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0506725
|
US9181182, 49
Show/Hide
|
C22H23ClN4O4
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0424850
|
2-propan-2-yloxy-5-[5-(4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-2-yl)-1,3,4-thiadiazol-2-yl]benzonitrile
Show/Hide
|
C18H18N6OS
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0520252
|
US9181182, 8
Show/Hide
|
C21H22Cl2N2O4
|
1
|
| 1 |
EC50 = 131 nM
|
|
|
|
CP0452404
|
5-[5-(3-methyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-2-yl)-1,3,4-thiadiazol-2-yl]-2-propan-2-yloxybenzonitrile
Show/Hide
|
C19H20N6OS
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0462423
|
2-(3-chloro-4-propan-2-yloxyphenyl)-5-(3-methyl-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-2-yl)-1,3,4-thiadiazole
Show/Hide
|
C18H20ClN5OS
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0449970
|
US9181182, 40
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 344 nM
|
|
|
|
CP0449969
|
US9181182, 36
Show/Hide
|
C27H25F3N4O3
|
1
|
| 1 |
EC50 = 501 nM
|
|
|
|
CP0447348
|
1-[[6-[(2-methoxy-4-propylphenyl)methoxy]-1,7-dimethyl-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H35NO4
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0385907
|
2-(3-chloro-4-propan-2-yloxyphenyl)-5-(4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-2-yl)-1,3,4-thiadiazole
Show/Hide
|
C17H18ClN5OS
|
1
|
| 1 |
EC50 = 630.96 nM
|
|
|
|
CP0449968
|
US9181182, 7
Show/Hide
|
C21H23ClN4O4
|
1
|
| 1 |
EC50 = 783 nM
|
|
|
|
CP0409263
|
2-(3-chloro-4-propan-2-yloxyphenyl)-5-(4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)-1,3,4-thiadiazole
Show/Hide
|
C17H18ClN5OS
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
|
|
CP0550185
|
US9181182, 42
Show/Hide
|
C23H24N4O4
|
1
|
| 1 |
EC50 = 1420 nM
|
|
|
|
CP0413427
|
US9181182, 2
Show/Hide
|
C20H34N2O2
|
1
|
| 1 |
EC50 = 1560 nM
|
|
|
|
CP0447739
|
2-[1-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3,5-dimethylpyrazol-4-yl]acetic acid
Show/Hide
|
C18H19ClN4O3S
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0569166
|
US9181182, 12
Show/Hide
|
C26H28FNO3
|
1
|
| 1 |
EC50 = 1820 nM
|
|
|
|
CP0556414
|
US9181182, 3
Show/Hide
|
C20H34N2O2
|
1
|
| 1 |
EC50 = 2110 nM
|
|
|
|
CP0383334
|
N-[6-(1H-benzimidazol-2-yl)-1,3-benzothiazol-2-yl]cyclohexanecarboxamide
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
EC50 = 19952.62 nM
|
|
|
|
CP0436118
|
US9181182, 1
Show/Hide
|
C18H32N2O2
|
1
|
| 1 |
EC50 > 25000 nM
|
|
|
|
CP0491424
|
US9181182, 41(b)
Show/Hide
|
C26H30Cl2N2O6
|
1
|
| 1 |
EC50 > 29000 nM
|
|
|
|
CP0521849
|
1-[5-bromo-7-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]ethanone
Show/Hide
|
C22H22BrF3N2O4S
|
1
|
| 1 |
EC50 = 31622.78 nM
|
|
|
|
CP0920431
|
GNF-Pf-590
Show/Hide
|
C24H21N5O2S
|
1
|
| 1 |
EC50 = 50118.72 nM
|
|
|
|
CP0556415
|
US9181182, 10
Show/Hide
|
C21H36N2O2
|
1
|
| 1 |
EC50 > 510 nM
|
|
|
|
CP0469987
|
US9181182, 9
Show/Hide
|
C21H36N2O2
|
1
|
| 1 |
EC50 > 860 nM
|
|
|
|
CP0519026
|
US9181182, 41(a)
Show/Hide
|
C21H22Cl2N2O4
|
1
|
| 1 |
EC50 > 1360 nM
|
|
|
|
CP0500452
|
US9181182, 58
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
EC50 > 2060 nM
|
|
|
|
CP0436120
|
US9181182, 59
Show/Hide
|
C27H29F3N2O2
|
1
|
| 1 |
EC50 > 2130 nM
|
|
|
|
CP0550184
|
US9181182, 39
Show/Hide
|
C27H29F3N2O3
|
1
|
| 1 |
EC50 > 3240 nM
|
|
|
|
CP0014534
|
(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
Show/Hide
|
C18H38NO5P
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0518015
|
methyl 2-chloro-4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzoate
Show/Hide
|
C22H21ClN2O3S
|
1
|
| 1 |
IC50 = 2.512 nM
|
|
|
|
CP0438157
|
(Z,Z)-5-[3-Chloro-4-((2S)-2,3-dihydroxy-propoxy)-benzylidene]-2-propylimino-3-otolyl-thiazolidin-4-one
Show/Hide
|
C23H25ClN2O4S
|
1
|
| 1 |
IC50 = 12.59 nM
|
|
|
|
CP0457877
|
N-(2-hydroxyethyl)-4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzamide
Show/Hide
|
C23H25N3O3S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0479297
|
2-hydroxyethyl 4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzoate
Show/Hide
|
C23H24N2O4S
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0457772
|
methyl 4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzoate
Show/Hide
|
C22H22N2O3S
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0435911
|
(Z)-5-[1-(4-cetyloxy-3-methoxyphenyl)-1-phenylmethylene]-sulfohydrazono isophthalic acid
Show/Hide
|
C38H50N2O8S
|
1
|
| 1 |
IC50 = 4280 nM
|
|
|
|
CP0405788
|
5-[[(Z)-[(4-hexadecoxy-3-methoxyphenyl)-piperidin-1-ylmethylidene]amino]sulfamoyl]benzene-1,3-dicarboxylic acid
Show/Hide
|
C37H55N3O8S
|
1
|
| 1 |
IC50 = 6180 nM
|
|
|
|
CP0453166
|
(E)-5-[1-(4-cetyloxy-3-methoxyphenyl)-1-phenylmethylene]-sulfohydrazono isophthalic acid
Show/Hide
|
C38H50N2O8S
|
1
|
| 1 |
IC50 = 6640 nM
|
|
|
|
CP0387271
|
4-(2-ethylbutyl)-N-[3-(4-fluorophenoxy)-5-pyridin-4-yloxyphenyl]-4-hydroxypiperidine-1-carboxamide
Show/Hide
|
C29H34FN3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0395995
|
US8975409, Example 9(3)
Show/Hide
|
C31H26F2N2O6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0409055
|
2-[4-[3-(4-fluorophenoxy)-5-[[3-hydroxy-3-(2-methylpropyl)pyrrolidine-1-carbonyl]amino]phenoxy]phenyl]-2-methylpropanoic acid
Show/Hide
|
C31H35FN2O6
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0176796
|
1-(2,6-dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propan-2-ylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
Show/Hide
|
C17H19Cl2N7O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0396135
|
1-(2-chloro-6-propan-2-yloxypyridin-4-yl)-3-[(1,3-dimethyl-4-propan-2-ylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
Show/Hide
|
C20H26ClN7O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0396136
|
1-[2-chloro-6-(cyclopropylmethoxy)pyridin-4-yl]-3-[(1,3-dimethyl-4-propan-2-ylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
Show/Hide
|
C21H26ClN7O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0440488
|
4-[(Z)-[3-(2-methylphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzoic acid
Show/Hide
|
C21H20N2O3S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0569589
|
4-[(Z)-[3-(2-hydroxyphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzoic acid
Show/Hide
|
C20H18N2O4S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0569590
|
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-[(Z)-[3-(2-hydroxyphenyl)-4-oxo-2-propylimino-1,3-thiazolidin-5-ylidene]methyl]benzoate
Show/Hide
|
C25H22N2O7S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
