Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[1-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3,5-dimethylpyrazol-4-yl]propanoic acid
    Show/Hide
 PubChem ID
CID: 127029100
Canonical SMILES
CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1nc(C)c(CCC(O)=O)c1C
    Show/Hide
Compound Formula C19H21ClN4O3S
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 19.95 nM
   TI
   LI
   LO
   TS
CL000466 McA-RH7777
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS