Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[6-[5-(3-cyano-4-propan-2-yloxyphenyl)-1,2,4-oxadiazol-3-yl]-5-methyl-3,4-dihydro-1H-isoquinolin-2-yl]propanoic acid
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 PubChem ID
CID: 44125170
SID: 84976940
Canonical SMILES
CC(C)Oc1ccc(cc1C#N)-c1nc(no1)-c1ccc2CN(CCC(O)=O)CCc2c1C
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Compound Formula C25H26N4O4
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 5.012 nM
   TI
   LI
   LO
   TS
2
EC50 = 5.623 nM
   TI
   LI
   LO
   TS
CL000466 McA-RH7777
 Cell Line Info 
Rattus norvegicus (Rat)  1
1
EC50 = 31.62 nM
   TI
   LI
   LO
   TS