Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[2-chloro-6-(cyclopropylmethoxy)pyridin-4-yl]-3-[(1,3-dimethyl-4-propan-2-ylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
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 PubChem ID
CID: 145966230
Canonical SMILES
CC(C)c1cc(NNC(=O)Nc2cc(Cl)nc(OCC3CC3)c2)nc2n(C)nc(C)c12
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Compound Formula C21H26ClN7O2
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS