Brief Information of the Compound and Protein
Compound Name
2-(3-chloro-4-propan-2-yloxyphenyl)-5-(4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)-1,3,4-thiadiazole
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PubChem ID
CID: 67284085
Canonical SMILES
CC(C)Oc1ccc(cc1Cl)-c1nnc(s1)-n1ncc2CNCCc12
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Compound Formula C17H18ClN5OS
Compound Structure
Protein Name
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 794.33 nM
   TI
   LI
   LO
   TS
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
EC50 = 398.11 nM
   TI
   LI
   LO
   TS