| Compound ID |
Compound Name |
Compound Formula |
|
CP0544921
|
US9000044, 60
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|
C27H18F7NO4S
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 5.6 nM
|
|
|
|
CP0480074
|
US9000044, 1
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|
C26H21FO4S
|
2
|
| 1 |
IC50 = 0.3 nM
|
|
|
| 2 |
IC50 = 2.9 nM
|
|
|
|
CP0483683
|
US9000044, 51
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|
C26H22FNO4S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0548932
|
US9000044, 35
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|
C23H24ClNO4S
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0480059
|
US9000044, 27
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|
C25H17ClF2O4S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0480075
|
US9000044, 2
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|
C25H18ClFO4S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0539067
|
US9000044, 46
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|
C23H22FNO4S
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0546456
|
2-[5-fluoro-2-methyl-3-[[6-oxo-1-[(2,4,5-trifluorophenyl)methyl]pyridazin-3-yl]methyl]indol-1-yl]acetic acid
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|
C23H17F4N3O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0458496
|
2-[3-[[1-[(2,3-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
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|
C24H19F3N2O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0483680
|
US9000044, 33
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|
C23H22ClNO4S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0459858
|
US9000044, 42
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|
C26H22FNO4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0469761
|
US9000044, 44
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|
C26H21ClFNO4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0574713
|
US9000044, 34
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|
C24H24ClNO4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0244713
|
2-[5-fluoro-2-methyl-3-[1-oxo-2-(4,4,4-trifluorobutyl)isoquinolin-4-yl]indol-1-yl]acetic acid
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|
C24H20F4N2O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0213000
|
2-[1-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
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|
C25H22F3N3O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0556963
|
US9000044, 6
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|
C26H18F4O5S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0539065
|
US9000044, 28
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|
C25H19ClFNO4S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0444397
|
2-[[(2aS,8R,8aR)-3-(3-fluorobenzoyl)-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylcarbamoyl]oxyacetic acid
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|
C24H23FN2O5
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0483678
|
US9000044, 10
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|
C25H17F3O4S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0539064
|
US9000044, 11
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|
C25H17F3O4S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0501519
|
US9000044, 53
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|
C30H30FNO5S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0556962
|
US9000044, 5
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|
C26H18F4O4S
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0416496
|
2-[[(2aS,8R,8aR)-3-[4-(trifluoromethoxy)benzoyl]-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylcarbamoyl]oxyacetic acid
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|
C25H23F3N2O6
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0466068
|
2-[[(2aS,8R,8aR)-3-(4-fluorobenzoyl)-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylcarbamoyl]oxyacetic acid
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|
C24H23FN2O5
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0051693
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-5-benzyl-2-methyl-4-oxo-6,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
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|
C30H28N2O5S
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0483681
|
US9000044, 37
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|
C22H22ClNO4S
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0501517
|
US9000044, 45
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|
C25H19ClFNO4S
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0574714
|
US9000044, 49
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|
C25H26FNO4S
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0539066
|
US9000044, 38
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|
C26H22ClNO4S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0556964
|
US9000044, 14
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|
C25H17F3O4S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0548933
|
US9000044, 50
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|
C22H22FNO4S
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0511770
|
4-[[(3aS,9R,9aR)-6-fluoro-4-[4-(trifluoromethoxy)benzoyl]-1,2,3,3a,9,9a-hexahydrocyclopenta[b]quinolin-9-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C27H26F4N2O5
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0512651
|
US9000044, 48
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|
C23H24FNO4S
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0441709
|
2-[5-chloro-3-[3-[2-(4-chlorophenoxy)ethyl]-4-oxophthalazin-1-yl]-2-methylindol-1-yl]acetic acid
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|
C27H21Cl2N3O4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0057623
|
2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
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|
C23H18F3N3O3
|
2
|
| 1 |
IC50 = 2 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0540519
|
2-[3-[[1-[(2,5-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H18F3N3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0205017
|
2-[1-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H22FN3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0251094
|
2-[1-[2-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C22H20FN3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0415232
|
2-[3-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-indol-1-yl]acetic acid
Show/Hide
|
C24H22FNO5S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0532322
|
2-[3-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-indol-1-yl]acetic acid
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|
C25H24FNO6S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0090170
|
2-[3-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H23FN2O6S
|
7
|
| 1 |
IC50 = 2.1 nM
|
|
|
| 2 |
IC50 = 2.4 nM
|
|
|
| 3 |
IC50 = 3.6 nM
|
|
|
| 4 |
IC50 = 4.1 nM
|
|
|
| 5 |
IC50 = 6.9 nM
|
|
|
| 6 |
IC50 = 7.1 nM
|
|
|
| 7 |
IC50 = 10 nM
|
|
|
|
CP0119066
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2,6,6-trimethyl-4-oxo-5,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C25H26N2O5S
|
7
|
| 1 |
IC50 = 2.1 nM
|
|
|
| 2 |
IC50 = 2.9 nM
|
|
|
| 3 |
IC50 = 4 nM
|
|
|
| 4 |
IC50 = 4.2 nM
|
|
|
| 5 |
IC50 = 5.5 nM
|
|
|
| 6 |
IC50 = 6.3 nM
|
|
|
| 7 |
IC50 = 7.7 nM
|
|
|
|
CP0448161
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-5-(difluoromethyl)-2-methyl-4-oxopyrrolo[3,2-c]pyridin-1-yl]acetic acid
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|
C24H20F2N2O5S
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0546945
|
US9000044, 23
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|
C25H17ClF2O4S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0563294
|
US9000044, 18
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|
C26H18ClF3O4S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0462625
|
US9000044, 55
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|
C23H22ClNO5S
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0516002
|
4-[[(3aS,9R,9aR)-7-fluoro-4-[4-(trifluoromethylsulfanyl)benzoyl]-1,2,3,3a,9,9a-hexahydrocyclopenta[b]quinolin-9-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C27H26F4N2O4S
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0512649
|
US9000044, 29
Show/Hide
|
C26H22ClNO4S
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0260457
|
2-[3-[2-(2,2-dimethylpropyl)-1-oxoisoquinolin-4-yl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C25H25FN2O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0382167
|
2-[5-fluoro-3-[[1-[(4-fluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
|
C24H20F2N2O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0382168
|
2-[5-fluoro-3-[[1-[(2-fluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H19F2N3O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0248258
|
2-[1-[2-[(3,5-dicyclopropyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C27H24F3N3O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0480597
|
2-[7-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-b]pyridazin-5-yl]acetic acid
Show/Hide
|
C25H22F3N3O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0533195
|
2-[1-[2-[(5-benzyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-chlorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C28H24ClN3O3
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0383739
|
2-[3-[(4-benzylsulfonylphenyl)methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H24N2O5S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0268081
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H22N2O5S
|
7
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
| 3 |
IC50 = 4.5 nM
|
|
|
| 4 |
IC50 = 4.9 nM
|
|
|
| 5 |
IC50 = 5 nM
|
|
|
| 6 |
IC50 = 6.5 nM
|
|
|
| 7 |
IC50 = 10 nM
|
|
|
|
CP0560178
|
US9000044, 40
Show/Hide
|
C30H30ClNO5S
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0472339
|
US9000044, 4
Show/Hide
|
C25H18ClFO4S
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0483684
|
US9000044, 52
Show/Hide
|
C27H24FNO5S
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0336527
|
2-[3-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H21FN2O5S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0063174
|
4-[[(3aS,9R,9aR)-7-fluoro-4-[4-(trifluoromethoxy)benzoyl]-1,2,3,3a,9,9a-hexahydrocyclopenta[b]quinolin-9-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C27H26F4N2O5
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0268082
|
2-[3-[[2-(benzenesulfonyl)-5-methoxyphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H24N2O6S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0516325
|
2-[3-[[2-(2-fluorophenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H21FN2O5S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0448160
|
2-[3-[[2-(benzenesulfonyl)-5-fluorophenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H21FN2O5S
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0563292
|
US9000044, 9
Show/Hide
|
C25H17Cl2FO4S
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0383729
|
2-[3-[[2-(4-methoxyphenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H24N2O6S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0417899
|
2-[3-[[2-(benzenesulfonyl)-5-bromophenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H21BrN2O5S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0479346
|
US9000044, 3
Show/Hide
|
C25H18ClFO4S
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0381469
|
2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxo-4,5-dihydropyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H20F3N3O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0248944
|
2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-pyridin-4-ylpyrazol-4-yl]acetic acid
Show/Hide
|
C24H21N3O4S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0124982
|
2-[5-fluoro-2-methyl-3-[1-oxo-2-(2,2,2-trifluoroethyl)isoquinolin-4-yl]indol-1-yl]acetic acid
Show/Hide
|
C22H16F4N2O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0473170
|
2-[5-fluoro-3-[[1-[(3-fluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
|
C24H20F2N2O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0499200
|
2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C24H19F3N2O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0251229
|
2-[1-[2-[[2-(cyclopropylmethyl)-4-methylpyrazol-3-yl]methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C26H28N4O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0481823
|
2-[1-[2-(tert-butylsulfanylmethyl)-4-(2-phenylethylcarbamoyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C30H33N3O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0481963
|
2-[5-fluoro-2-methyl-3-(2-methylsulfonyl-3,4-dihydro-1H-isoquinolin-5-yl)indol-1-yl]acetic acid
Show/Hide
|
C21H21FN2O4S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0325233
|
2-[3-[[2-(3-chlorophenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H21ClN2O5S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0248109
|
2-[1-[2-[[cyclopropanecarbonyl(2-phenoxyethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C30H28F3N3O4
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0428234
|
2-[1-[2-[[cyclopropanecarbonyl(2-methoxyethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
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C25H26F3N3O4
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1
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| 1 |
IC50 = 4 nM
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CP0409116
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2-[1-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-2,6-dimethylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
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C25H23FN2O5S
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1
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| 1 |
IC50 = 4 nM
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CP0469762
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US9000044, 47
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C24H24FNO4S
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1
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| 1 |
IC50 = 4.1 nM
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CP0248107
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2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-b]pyridazin-5-yl]acetic acid
Show/Hide
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C24H24F3N3O3
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1
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| 1 |
IC50 = 4.2 nM
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CP0268091
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2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-fluoroindazol-1-yl]acetic acid
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C23H21F4N3O3
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1
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| 1 |
IC50 = 4.3 nM
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CP0469760
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US9000044, 22
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C25H17Cl3O4S
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1
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| 1 |
IC50 = 4.4 nM
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CP0053336
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C23H24FN3O3
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1
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| 1 |
IC50 = 4.7 nM
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CP0500324
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US9000044, 32
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C25H19Cl2NO4S
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1
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| 1 |
IC50 = 4.7 nM
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CP0119067
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2,5-dimethyl-4-oxopyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C24H22N2O5S
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1
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| 1 |
IC50 = 4.9 nM
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CP0547836
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2-[5-fluoro-3-[[1-[[4-(2-hydroxypropan-2-yl)phenyl]methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C26H26FN3O4
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1
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| 1 |
IC50 = 5 nM
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CP0466975
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2-[3-[[1-[(2,6-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H18F3N3O3
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1
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| 1 |
IC50 = 5 nM
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CP0513124
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2-[3-(1-benzyl-6-oxopyridin-3-yl)-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H19FN2O3
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1
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| 1 |
IC50 = 5 nM
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CP0205016
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2-[3-[2-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-methylpyrrolo[3,2-b]pyridin-1-yl]acetic acid
Show/Hide
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C23H20F3N3O3
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1
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| 1 |
IC50 = 5 nM
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CP0248105
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C23H25N3O3
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1
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| 1 |
IC50 = 5 nM
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CP0463113
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2-[8-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-a]pyrimidin-6-yl]acetic acid
Show/Hide
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C25H22F3N3O3
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1
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| 1 |
IC50 = 5 nM
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CP0399479
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2-[3-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-2,6,6-trimethyl-4-oxo-5,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C25H25FN2O5S
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1
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| 1 |
IC50 = 5 nM
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CP0556345
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2-[3-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-2,6,6-trimethyl-4-oxo-5,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C26H27FN2O6S
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1
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| 1 |
IC50 = 5 nM
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CP0379513
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2-[1-[2-[[benzylcarbamoyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C28H27F3N4O3
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1
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| 1 |
IC50 = 5 nM
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CP0192069
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2-[7-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-6-methylpyrrolo[1,2-c]pyrimidin-5-yl]acetic acid
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C24H21FN2O5S
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1
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| 1 |
IC50 = 5 nM
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CP0248106
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2-[1-[4-chloro-2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C23H24ClN3O3
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1
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| 1 |
IC50 = 5.2 nM
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CP0472340
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US9000044, 13
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C25H17Cl2FO4S
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1
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| 1 |
IC50 = 5.4 nM
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CP0512652
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US9000044, 56
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C21H20ClNO5S
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1
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| 1 |
IC50 = 5.6 nM
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CP0067960
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethoxy)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C24H24F3N3O4
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1
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| 1 |
IC50 = 5.8 nM
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CP0532208
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C24H27N3O3
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1
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| 1 |
IC50 = 5.9 nM
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CP0500499
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2-[5-fluoro-3-[[1-[(3-fluoropyridin-4-yl)methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C22H18F2N4O3
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1
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| 1 |
IC50 = 6 nM
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CP0124983
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2-[5-fluoro-2-methyl-3-(1-oxo-2-propan-2-ylisoquinolin-4-yl)indol-1-yl]acetic acid
Show/Hide
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C23H21FN2O3
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1
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| 1 |
IC50 = 6 nM
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CP0458490
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2-[3-[1-[(2,6-difluorophenyl)methyl]-6-oxopyridin-3-yl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H17F3N2O3
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1
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| 1 |
IC50 = 6 nM
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CP0514384
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2-[5-fluoro-3-[[1-[(4-fluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H19F2N3O3
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1
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| 1 |
IC50 = 6 nM
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CP0573253
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2-[5-fluoro-3-[1-[(4-fluorophenyl)methyl]-6-oxopyridin-3-yl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H18F2N2O3
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1
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| 1 |
IC50 = 6 nM
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CP0054194
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2-[1-[4-chloro-2-[(3,5-dicyclopropyl-1,2-oxazol-4-yl)methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C26H24ClN3O3
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1
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| 1 |
IC50 = 6 nM
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CP0152548
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2-[3-[2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindol-1-yl]acetic acid
Show/Hide
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C24H20F4N4O2
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1
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| 1 |
IC50 = 6 nM
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CP0379896
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2-[3-[3-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C22H19FN2O3
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1
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| 1 |
IC50 = 6 nM
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CP0481943
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-5-(1,1,1-trifluoropropan-2-yl)-6,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C26H25F3N2O5S
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1
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| 1 |
IC50 = 6 nM
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CP0067963
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2-[1-[2-[[ethyl-(2-phenylacetyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C28H26F3N3O3
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1
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| 1 |
IC50 = 6 nM
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CP0442511
|
US9000044, 57
Show/Hide
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C21H20FNO5S
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1
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| 1 |
IC50 = 6.1 nM
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CP0526406
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US9000044, 36
Show/Hide
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C25H26ClNO4S
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1
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| 1 |
IC50 = 6.1 nM
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CP0248268
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2-[3-[[2-(3-fluorophenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C23H21FN2O5S
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1
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| 1 |
IC50 = 6.2 nM
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CP0470139
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US9000044, 65
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C26H20ClNO3
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1
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| 1 |
IC50 = 6.2 nM
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CP0129137
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2-[4-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid
Show/Hide
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C23H21ClF3N3O3
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1
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| 1 |
IC50 = 6.3 nM
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CP0399478
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2-[2-methyl-4-oxo-3-[[2-[4-(trifluoromethoxy)phenyl]sulfonylphenyl]methyl]-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C24H21F3N2O6S
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1
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| 1 |
IC50 = 6.6 nM
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CP0500323
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US9000044, 31
Show/Hide
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C26H21Cl2NO4S
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1
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| 1 |
IC50 = 6.7 nM
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CP0484462
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2-[5-fluoro-3-[[1-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C26H20F7N3O4
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1
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| 1 |
IC50 = 7 nM
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CP0042334
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2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
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C25H22N2O4S
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1
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| 1 |
IC50 = 7 nM
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CP0382166
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2-[3-[[1-[(2,6-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C24H19F3N2O3
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1
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| 1 |
IC50 = 7 nM
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CP0248253
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2-[6-benzyl-1-[2-[(3,5-dimethyl-1,2,4-triazol-4-yl)methyl]-4-methylphenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C28H27N5O2
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1
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| 1 |
IC50 = 7 nM
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CP0483682
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2-[6-benzyl-1-[4-chloro-2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C30H26ClN3O3
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1
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| 1 |
IC50 = 7 nM
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CP0533217
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2,5-dimethyl-4-oxo-6,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C24H24N2O5S
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1
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| 1 |
IC50 = 7 nM
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CP0146136
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2-[8-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-2-methylpyrrolo[1,2-a]pyrimidin-6-yl]acetic acid
Show/Hide
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C24H24F3N3O3
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1
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| 1 |
IC50 = 7 nM
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CP0318457
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2-[1-[2-[[(2-cyclopropylacetyl)-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C25H26F3N3O3
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1
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| 1 |
IC50 = 7 nM
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CP0563293
|
US9000044, 17
Show/Hide
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C25H18Cl2O4S
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1
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| 1 |
IC50 = 7 nM
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CP0442614
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2-[5-chloro-3-[1-[(2,6-difluorophenyl)methyl]-6-oxopyridin-3-yl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H17ClF2N2O3
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1
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| 1 |
IC50 = 8 nM
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CP0442616
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2-[3-[[1-[(2,5-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C24H19F3N2O3
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1
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| 1 |
IC50 = 8 nM
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CP0480741
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2-[5-fluoro-3-[[1-[(3-fluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H19F2N3O3
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1
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| 1 |
IC50 = 8 nM
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CP0499201
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2-[5-fluoro-3-[[1-[(2-fluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C24H20F2N2O3
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1
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| 1 |
IC50 = 8 nM
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CP0481965
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(2-phenylethylcarbamoyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C32H34N4O4
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1
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| 1 |
IC50 = 8 nM
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CP0385007
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2-[4-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-5-methyl-2-phenylimidazol-1-yl]acetic acid
Show/Hide
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C25H21FN2O4S
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1
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| 1 |
IC50 = 8 nM
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CP0563291
|
US9000044, 63
Show/Hide
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C26H22ClNO4S
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1
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| 1 |
IC50 = 8.3 nM
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CP0459599
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2-[3-[[2-(4-chlorophenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C23H21ClN2O5S
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1
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| 1 |
IC50 = 8.5 nM
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CP0555215
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C23H20N2O5S
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1
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| 1 |
IC50 = 8.6 nM
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CP0574709
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US9000044, 62
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C26H19ClF3NO4S
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1
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| 1 |
IC50 = 8.9 nM
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CP0439894
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2-[3-[(1-benzyl-6-oxopyridazin-3-yl)methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H20FN3O3
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2
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| 1 |
IC50 = 9 nM
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| 2 |
IC50 = 10 nM
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CP0248255
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2-[1-[2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-6-fluoroindol-3-yl]acetic acid
Show/Hide
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C24H20F4N4O2
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1
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| 1 |
IC50 = 9 nM
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CP0379947
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2-[1-[4-chloro-2-[[3-methyl-5-(2-phenylethyl)-1,2,4-triazol-4-yl]methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C28H26ClN5O2
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1
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| 1 |
IC50 = 9 nM
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CP0483417
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-5-propan-2-yl-6,7-dihydropyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C26H28N2O5S
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1
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| 1 |
IC50 = 9 nM
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CP0052912
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C23H22F3N3O3
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1
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| 1 |
IC50 = 9 nM
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CP0352580
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2-[1-[2-[[ethyl-(2-methoxyacetyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C23H24F3N3O4
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1
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| 1 |
IC50 = 9 nM
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CP0555198
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2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-methylindazol-1-yl]acetic acid
Show/Hide
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C24H24F3N3O3
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1
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| 1 |
IC50 = 9 nM
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CP0954554
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[6-Chloro-1-(4-methanesulfonyl-2-trifluoromethyl-benzyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-aceticacid
Show/Hide
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C19H16ClF3N2O4S
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2
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| 1 |
IC50 = 9 nM
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| 2 |
Ki = 5 nM
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CP0512648
|
US9000044, 8
Show/Hide
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C25H17Cl2FO4S
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1
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| 1 |
IC50 = 9.1 nM
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CP0383896
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4-[[(2aS,8R,8aR)-3-(3-fluorobenzoyl)-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
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C25H25FN2O4
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1
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| 1 |
IC50 = 9.3 nM
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CP0569459
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2-[3-[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C22H16F3N3O3
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1
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| 1 |
IC50 = 10 nM
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CP0382165
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2-[3-(1-benzyl-6-oxopyridin-3-yl)-5-chloro-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H19ClN2O3
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1
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| 1 |
IC50 = 10 nM
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CP0067962
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2-[1-[2-[[acetyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C22H22F3N3O3
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1
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| 1 |
IC50 = 10 nM
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CP0152546
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2-[1-[2-[(2,4-dimethylpyrazol-3-yl)methyl]-4-fluorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C22H21FN4O2
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1
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| 1 |
IC50 = 10 nM
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CP0417898
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2-[3-[[2-(benzenesulfonyl)-4-(methylcarbamoyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C25H25N3O6S
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1
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| 1 |
IC50 = 10 nM
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CP0052914
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-ethylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C25H26F3N3O3
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1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0146132
|
2-[4-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindazol-1-yl]acetic acid
Show/Hide
|
C23H20ClF4N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0393995
|
2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0418290
|
2-[1-[2-[[cyclobutanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C25H26F3N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0381470
|
2-[3-(3-benzyl-4-oxophthalazin-1-yl)-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C26H20FN3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0481601
|
2-[3-(3-benzyl-4-oxophthalazin-1-yl)-5-chloro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C26H20ClN3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0459486
|
2-[5-fluoro-2-methyl-3-[[6-oxo-1-(4,4,4-trifluorobutyl)pyridazin-3-yl]methyl]indol-1-yl]acetic acid
Show/Hide
|
C20H19F4N3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0566200
|
2-[3-[(1-benzyl-6-oxopyridin-3-yl)methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C24H21FN2O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0559112
|
2-[1-[2-[(3-benzyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-chlorophenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C27H24ClN5O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0537561
|
2-[3-[[2-(benzenesulfonyl)-4-methoxycarbonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C25H24N2O7S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0248102
|
2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-(difluoromethyl)pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H22F5N3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0379325
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]indol-1-yl]acetic acid
Show/Hide
|
C23H23FN2O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0428206
|
2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]-6-(trifluoromethyl)indol-3-yl]acetic acid
Show/Hide
|
C24H23F3N2O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0490050
|
2-[1-[2-[[cyclopropanecarbonyl(cyclopropylmethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C26H26F3N3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0547835
|
2-[5-fluoro-2-methyl-3-[[6-oxo-1-(pyridin-4-ylmethyl)pyridazin-3-yl]methyl]indol-1-yl]acetic acid
Show/Hide
|
C22H19FN4O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0510278
|
2-[3-[[2-(3-methoxyphenyl)sulfonylphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H24N2O6S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0444401
|
4-[[(3aS,9R,9aR)-6-chloro-7-fluoro-4-[4-(trifluoromethoxy)benzoyl]-1,2,3,3a,9,9a-hexahydrocyclopenta[b]quinolin-9-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C27H25ClF4N2O5
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0478535
|
4-[[(2aS,8R,8aR)-3-(4-fluorobenzoyl)-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C25H25FN2O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0500322
|
US9000044, 20
Show/Hide
|
C26H18ClF3O5S
|
1
|
| 1 |
IC50 = 12.9 nM
|
|
|
|
CP0090171
|
2-[3-[[2-(benzenesulfonyl)-4-(trifluoromethyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H21F3N2O5S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0268086
|
2-[8-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[1,2-a]pyrimidin-6-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0883081
|
{1-[1-(4-Methanesulfonyl-phenyl)-ethyl]-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}-aceticacid
Show/Hide
|
C19H20N2O4S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0512650
|
US9000044, 39
Show/Hide
|
C27H24ClNO5S
|
1
|
| 1 |
IC50 = 13.2 nM
|
|
|
|
CP0416186
|
2-[3-(2-benzyl-1-oxoisoquinolin-4-yl)-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C27H21FN2O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0114154
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid
Show/Hide
|
C23H24F3NO4
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0271723
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]-5-(trifluoromethyl)indol-1-yl]acetic acid
Show/Hide
|
C24H22F4N2O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0326125
|
2-[1-[2-[[cyclopropanecarbonyl(2-hydroxyethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H24F3N3O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0462627
|
US9000044, 12
Show/Hide
|
C27H17F7O4S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0153758
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C24H20FNO4S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
IC50 = 16 nM
|
|
|
|
CP0472035
|
2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-2,6-dimethylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H22N2O4S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0081954
|
2-[1-[(2-chloro-4-methylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C18H17ClN2O4S
|
2
|
| 1 |
IC50 = 14 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0391315
|
2-[3-[(1-benzyl-6-oxopyridazin-3-yl)methyl]-5-chloro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H20ClN3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0052915
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyrrolo[3,2-b]pyridin-1-yl]acetic acid
Show/Hide
|
C24H21F6N3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0089062
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindazol-1-yl]acetic acid
Show/Hide
|
C23H21F4N3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0248101
|
2-[5-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-fluoroindazol-1-yl]acetic acid
Show/Hide
|
C23H20ClF4N3O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0326123
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[3,2-b]pyridin-1-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0512647
|
US9000044, 7
Show/Hide
|
C26H18F4O5S
|
1
|
| 1 |
IC50 = 15.8 nM
|
|
|
|
CP0381467
|
2-[5-fluoro-2-methyl-3-[[6-oxo-1-[[4-(trifluoromethyl)phenyl]methyl]pyridazin-3-yl]methyl]indol-1-yl]acetic acid
Show/Hide
|
C24H19F4N3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0391986
|
2-[3-[(1-benzyl-6-oxo-4,5-dihydropyridazin-3-yl)methyl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H22FN3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0481603
|
2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5-bromo-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H18BrN3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0520623
|
2-[3-(3-benzyl-4-oxophthalazin-1-yl)-2-methylindol-1-yl]acetic acid
Show/Hide
|
C26H21N3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0439893
|
2-[5-fluoro-2-methyl-3-[6-oxo-1-(4,4,4-trifluorobutyl)pyridin-3-yl]indol-1-yl]acetic acid
Show/Hide
|
C20H18F4N2O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0190339
|
2-[1-[2-[(3,5-dimethyl-1,2,4-triazol-4-yl)methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C22H23N5O2
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0417902
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-4-chloro-2-methylpyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H19ClN2O4S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0146214
|
2-[5-chloro-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid
Show/Hide
|
C23H21ClF3N3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0090559
|
2-[1-[(2-chloro-4-ethylsulfonylphenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C19H19ClN2O4S
|
2
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0514379
|
2-[3-[1-[(2,4-difluorophenyl)methyl]-6-oxopyridin-3-yl]-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H17F3N2O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0146213
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methylindazol-1-yl]acetic acid
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0248104
|
2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-fluorophenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C22H22FN3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0326124
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-5-methylpyrrolo[3,2-b]pyridin-1-yl]acetic acid
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0565391
|
2-[5-fluoro-2-methyl-3-[[6-oxo-1-(2,2,2-trifluoroethyl)pyridazin-3-yl]methyl]indol-1-yl]acetic acid
Show/Hide
|
C18H15F4N3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0409117
|
2-[1-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H21FN2O5S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0463106
|
3-(benzenesulfonyl)-4-[[1-(carboxymethyl)-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-3-yl]methyl]benzoic acid
Show/Hide
|
C24H22N2O7S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0089061
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0248267
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indol-1-yl]acetic acid
Show/Hide
|
C24H23F3N2O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0560177
|
US9000044, 66
Show/Hide
|
C26H21ClN2O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0081955
|
Fevipiprant
Show/Hide
|
C19H17F3N2O4S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
Ki = 4 nM
|
|
|
|
CP0881814
|
[6-Chloro-1-(4-methanesulfonyl-benzyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid
Show/Hide
|
C18H17ClN2O4S
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0539365
|
US9000044, 19
Show/Hide
|
C26H18ClF3O5S
|
1
|
| 1 |
IC50 = 19.7 nM
|
|
|
|
CP0381468
|
2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H19F2N3O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0462007
|
2-[5-fluoro-3-[1-[(4-fluorophenyl)methyl]-6-oxopyridazin-3-yl]-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H17F2N3O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0206870
|
2-[3-[2-[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindol-1-yl]acetic acid
Show/Hide
|
C23H18F4N2O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0418275
|
2-[3-[[2-(benzenesulfonyl)-3-methoxyphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H24N2O6S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0499198
|
2-[3-[1-[(2,6-difluorophenyl)methyl]-6-oxopyridin-3-yl]-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H18F2N2O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0054111
|
2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C18H18N2O4S
|
2
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
|
CP0490053
|
2-[2-methyl-3-[(2-morpholin-4-ylsulfonylphenyl)methyl]-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C21H25N3O6S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0445485
|
2-[1-[[4-ethylsulfonyl-2-(trifluoromethyl)phenyl]methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C20H19F3N2O4S
|
2
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0567109
|
US9000044, 26
Show/Hide
|
C25H17Cl3O4S
|
1
|
| 1 |
IC50 = 22.1 nM
|
|
|
|
CP0569463
|
2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H18FN3O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0559113
|
2-[3-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyrrolo[3,2-b]pyridin-1-yl]acetic acid
Show/Hide
|
C25H19F6N3O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0263118
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyindazol-1-yl]acetic acid
Show/Hide
|
C24H24F3N3O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0248945
|
2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-3-(4-chlorophenyl)-5-methylpyrazol-4-yl]acetic acid
Show/Hide
|
C25H21ClN2O4S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0444403
|
4-[[(2aS,8R,8aR)-3-[4-(trifluoromethoxy)benzoyl]-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C26H25F3N2O5
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0539062
|
US9000044, 54
Show/Hide
|
C20H17FO4S
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0398865
|
2-[3-[[2-[benzyl(methyl)sulfamoyl]phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C25H27N3O5S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0246918
|
2-[2-methyl-1-[(2-methyl-4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C19H20N2O4S
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2
|
| 1 |
IC50 = 26 nM
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| 2 |
Ki = 31 nM
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CP0379897
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2-[3-[2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetic acid
Show/Hide
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C23H22F3N3O3
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1
|
| 1 |
IC50 = 27 nM
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CP0546455
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2-[3-[[1-[(2,4-difluorophenyl)methyl]-6-oxopyridazin-3-yl]methyl]-5,7-difluoro-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H17F4N3O3
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1
|
| 1 |
IC50 = 28 nM
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CP0569464
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5-chloro-2-methylindol-1-yl]acetic acid
Show/Hide
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C22H18ClN3O3
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1
|
| 1 |
IC50 = 28 nM
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CP0418276
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2-[3-[[2-(benzenesulfonyl)-5-cyanophenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C24H21N3O5S
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1
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| 1 |
IC50 = 28 nM
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CP0459595
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2-[3-[(2-cyclohexylsulfonylphenyl)methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C23H28N2O5S
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1
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| 1 |
IC50 = 28 nM
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CP0559142
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2-[1-[2-[[cyclopropanecarbonyl(propan-2-yl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C25H26F3N3O3
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1
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| 1 |
IC50 = 28 nM
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CP0192068
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2-[7-[[2-(benzenesulfonyl)phenyl]methyl]-6-methylpyrrolo[1,2-c]pyrimidin-5-yl]acetic acid
Show/Hide
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C23H20N2O4S
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1
|
| 1 |
IC50 = 28 nM
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CP0481600
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2-[3-[(3-benzyl-4-oxophthalazin-1-yl)methyl]-5-chloro-2-methylindol-1-yl]acetic acid
Show/Hide
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C27H22ClN3O3
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1
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| 1 |
IC50 = 29 nM
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CP0539063
|
US9000044, 64
Show/Hide
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C21H18ClNO3
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1
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| 1 |
IC50 = 29.2 nM
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CP0057143
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2-[4-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
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C25H21FN2O4S
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2
|
| 1 |
IC50 = 30 nM
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| 2 |
IC50 = 70 nM
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CP0481960
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2-[6-methyl-1-[4-methyl-2-[(2-phenylimidazol-1-yl)methyl]phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C27H24N4O2
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1
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| 1 |
IC50 = 30 nM
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CP0502399
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2-(1-(4-cyano-3-ethoxyphenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid
Show/Hide
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C19H17N3O5S
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2
|
| 1 |
IC50 = 31 nM
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| 2 |
Ki = 43 nM
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CP0535649
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2-[3-[(1-benzyl-6-oxopyridazin-3-yl)methyl]-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H21N3O3
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1
|
| 1 |
IC50 = 32 nM
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CP0481977
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2-[3-[[2-[hydroxy(phenyl)methyl]phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C24H24N2O4
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1
|
| 1 |
IC50 = 32 nM
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CP0326952
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2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[1,2-c]pyrimidin-5-yl]acetic acid
Show/Hide
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C23H22F3N3O3
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1
|
| 1 |
IC50 = 32 nM
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CP0379512
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2-[4-cyano-3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indazol-1-yl]acetic acid
Show/Hide
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C24H21F3N4O3
|
1
|
| 1 |
IC50 = 33 nM
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CP0569462
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-2,5-dimethylindol-1-yl]acetic acid
Show/Hide
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C23H21N3O3
|
1
|
| 1 |
IC50 = 34 nM
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CP0544926
|
US9000044, 30
Show/Hide
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C26H19ClF3NO5S
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1
|
| 1 |
IC50 = 34.3 nM
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CP0482486
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2-[1-[[2-(4-fluorophenyl)sulfonyl-5-methoxyphenyl]methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
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C26H23FN2O5S
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1
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| 1 |
IC50 = 36 nM
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CP0190341
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2-[3-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-fluorophenyl]-5-(trifluoromethyl)indol-1-yl]acetic acid
Show/Hide
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C25H20F4N2O3
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1
|
| 1 |
IC50 = 37 nM
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CP0237540
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2-[3-[2-[(5-cyclopropyl-3-methyl-1,2-oxazol-4-yl)methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindol-1-yl]acetic acid
Show/Hide
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C25H20F4N2O3
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1
|
| 1 |
IC50 = 37 nM
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CP0271724
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indol-3-yl]acetic acid
Show/Hide
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C24H23F3N2O3
|
1
|
| 1 |
IC50 = 37 nM
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CP0057144
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2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
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C25H22N2O4S
|
3
|
| 1 |
IC50 = 40 nM
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|
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| 2 |
IC50 = 85 nM
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| 3 |
IC50 = 520 nM
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CP0352579
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-methylsulfonylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C24H27N3O5S
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1
|
| 1 |
IC50 = 40 nM
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CP0248457
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2-[2-methyl-1-[[4-methylsulfonyl-3-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C19H17F3N2O4S
|
2
|
| 1 |
IC50 = 40 nM
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| 2 |
Ki = 22 nM
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CP0404910
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2-(1-(4-chloro-3-cyanophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid
Show/Hide
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C17H12ClN3O4S
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2
|
| 1 |
IC50 = 41 nM
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|
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| 2 |
Ki = 35 nM
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CP0382181
|
2-[3-(1-benzyl-6-oxopyridin-3-yl)-2-methylindol-1-yl]acetic acid
Show/Hide
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C23H20N2O3
|
1
|
| 1 |
IC50 = 42 nM
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CP0146156
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C23H22F3N3O3
|
1
|
| 1 |
IC50 = 43 nM
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CP0515999
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4-[[(2aS,8R,8aR)-3-[3-(trifluoromethoxy)benzoyl]-2,2a,8,8a-tetrahydro-1H-cyclobuta[b]quinolin-8-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
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C26H25F3N2O5
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1
|
| 1 |
IC50 = 43 nM
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|
|
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CP0459857
|
US9000044, 25
Show/Hide
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C27H17ClF6O4S
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1
|
| 1 |
IC50 = 44.7 nM
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CP0113156
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2-[1-[bis(4-fluorophenyl)methyl]-5-methyl-3-pyridin-4-ylpyrazol-4-yl]acetic acid
Show/Hide
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C24H19F2N3O2
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1
|
| 1 |
IC50 = 46 nM
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CP0147600
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2-[2-methyl-1-[(4-propan-2-ylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C20H22N2O4S
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2
|
| 1 |
IC50 = 46 nM
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|
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| 2 |
Ki = 98 nM
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CP0385003
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2-[8-[[2-(benzenesulfonyl)phenyl]methyl]-2-(trifluoromethyl)pyrrolo[1,2-a]pyrimidin-6-yl]acetic acid
Show/Hide
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C23H17F3N2O4S
|
1
|
| 1 |
IC50 = 47 nM
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CP0313886
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2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-1-methylindazol-5-yl]acetic acid
Show/Hide
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C24H24F3N3O3
|
1
|
| 1 |
IC50 = 48 nM
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CP0326950
|
2-[7-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-2-methylindazol-5-yl]acetic acid
Show/Hide
|
C24H24F3N3O3
|
1
|
| 1 |
IC50 = 48 nM
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CP0481822
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-cyclopropylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C26H26F3N3O3
|
1
|
| 1 |
IC50 = 49 nM
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CP0469834
|
2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-[3-(trifluoromethyl)phenyl]pyrazol-1-yl]acetic acid
Show/Hide
|
C26H21F3N2O4S
|
1
|
| 1 |
IC50 = 50 nM
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CP0555199
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2-[6-methyl-1-[2-[(2-propylbenzimidazol-1-yl)methyl]phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C27H26N4O2
|
1
|
| 1 |
IC50 = 51 nM
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CP0442615
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2-[5-fluoro-2-methyl-3-[[6-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]methyl]indol-1-yl]acetic acid
Show/Hide
|
C19H16F4N2O3
|
1
|
| 1 |
IC50 = 52 nM
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CP0248103
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-(trifluoromethyl)pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C24H21F6N3O3
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1
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| 1 |
IC50 = 54 nM
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CP0533194
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2-[1-[4-chloro-2-[(3-cyclopropyl-5-methyl-1,2,4-triazol-4-yl)methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C23H22ClN5O2
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1
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| 1 |
IC50 = 56 nM
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CP0466069
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4-[[(3aS,9R,9aR)-6-chloro-4-[4-(trifluoromethoxy)benzoyl]-1,2,3,3a,9,9a-hexahydrocyclopenta[b]quinolin-9-yl]-cyclopropylamino]-4-oxobutanoic acid
Show/Hide
|
C27H26ClF3N2O5
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1
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| 1 |
IC50 = 59 nM
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CP0504749
|
2-[4-[[2-(benzenesulfonyl)-5-methoxyphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H24N2O5S
|
1
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| 1 |
IC50 = 60 nM
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CP0942273
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[1-(4-Cyano-3-propoxy-benzenesulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid
Show/Hide
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C20H19N3O5S
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2
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| 1 |
IC50 = 60 nM
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| 2 |
Ki = 50 nM
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CP0460300
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2-[3-[2-[(2,4-dimethylpyrazol-3-yl)methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindol-1-yl]acetic acid
Show/Hide
|
C23H19F4N3O2
|
1
|
| 1 |
IC50 = 64 nM
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CP0147599
|
2-[1-[[2,4-bis(trifluoromethyl)phenyl]methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C19H14F6N2O2
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2
|
| 1 |
IC50 = 64 nM
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|
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| 2 |
Ki = 29 nM
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CP0385005
|
2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-4-oxophthalazin-1-yl]acetic acid
Show/Hide
|
C23H18N2O5S
|
1
|
| 1 |
IC50 = 65 nM
|
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CP0396685
|
2-[5-methyl-3-phenyl-1-[(2-piperidin-1-ylsulfonylphenyl)methyl]pyrazol-4-yl]acetic acid
Show/Hide
|
C24H27N3O4S
|
1
|
| 1 |
IC50 = 66 nM
|
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CP0524979
|
2-[4-[[2-(benzenesulfonyl)-4-methoxyphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H24N2O5S
|
1
|
| 1 |
IC50 = 70 nM
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CP0540078
|
2-[4-[[2-(2,6-dimethylphenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C27H26N2O4S
|
1
|
| 1 |
IC50 = 70 nM
|
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CP0558062
|
2-[5-fluoro-2-methyl-3-(6-oxo-1-propan-2-ylpyridin-3-yl)indol-1-yl]acetic acid
Show/Hide
|
C19H19FN2O3
|
1
|
| 1 |
IC50 = 70 nM
|
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|
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CP0551624
|
2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5,7-difluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H17F2N3O3
|
1
|
| 1 |
IC50 = 76 nM
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CP0881808
|
{2-Methyl-1-[1-(4-trifluoromethyl-phenyl)-ethyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}-acetic acid
Show/Hide
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C19H17F3N2O2
|
2
|
| 1 |
IC50 = 80 nM
|
|
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| 2 |
Ki = 45 nM
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CP0086384
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2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-3,5-dimethylpyrazol-4-yl]acetic acid
Show/Hide
|
C20H20N2O4S
|
1
|
| 1 |
IC50 = 81 nM
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CP0146154
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]imidazo[1,5-a]pyridin-1-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
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1
|
| 1 |
IC50 = 82 nM
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CP0458489
|
2-[5-fluoro-2-methyl-3-[6-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]indol-1-yl]acetic acid
Show/Hide
|
C18H14F4N2O3
|
1
|
| 1 |
IC50 = 84 nM
|
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CP0850986
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{1-[1-(4-Chloro-phenyl)-ethyl]-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}-acetic acid
Show/Hide
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C18H17ClN2O2
|
2
|
| 1 |
IC50 = 84 nM
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| 2 |
Ki = 100 nM
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CP0452577
|
2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-pyrimidin-5-ylpyrazol-1-yl]acetic acid
Show/Hide
|
C23H20N4O4S
|
1
|
| 1 |
IC50 = 87 nM
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CP0085853
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2-[5-methyl-1-[(2-morpholin-4-ylsulfonylphenyl)methyl]-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
|
C23H25N3O5S
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
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CP0481602
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5-chloro-7-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H17ClFN3O3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
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CP0418273
|
(2S)-2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]propanoic acid
Show/Hide
|
C24H24N2O5S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
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CP0503954
|
2-(1-(4-fluoro-3-methoxyphenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid
Show/Hide
|
C17H15FN2O5S
|
2
|
| 1 |
IC50 = 91 nM
|
|
|
| 2 |
Ki = 56 nM
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CP0938175
|
[1-(3-Chloro-4-methanesulfonyl-benzyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid
Show/Hide
|
C18H17ClN2O4S
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
Ki = 27 nM
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CP0352581
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2-[1-[2-[[ethyl(pyridine-2-carbonyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C26H23F3N4O3
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
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CP0113157
|
2-[1-[(2-benzylphenyl)methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
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CP0498557
|
2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5-methoxy-2-methylindol-1-yl]acetic acid
Show/Hide
|
C23H21N3O4
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
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CP0549321
|
2-[3-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-2-methyl-4,5,6,7-tetrahydroindol-1-yl]acetic acid
Show/Hide
|
C24H24FNO4S
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
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CP0416185
|
2-[5-fluoro-2-methyl-3-(1-oxo-2-propan-2-yl-5,6,7,8-tetrahydroisoquinolin-4-yl)indol-1-yl]acetic acid
Show/Hide
|
C23H25FN2O3
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
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CP0546457
|
2-[3-(3-benzyl-4-oxo-4a,5,6,7,8,8a-hexahydrophthalazin-1-yl)-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C26H26FN3O3
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
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CP0483789
|
2-[4-[[2-(4-chlorophenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C25H21ClN2O4S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
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CP0483791
|
2-[4-[[2-(2-fluorophenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C25H21FN2O4S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
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CP0555843
|
2-[4-[(2-benzylsulfonylphenyl)methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H24N2O4S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
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CP0067961
|
2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methylindol-3-yl]acetic acid
Show/Hide
|
C25H25F3N2O3
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
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CP0418224
|
2-[3-[(2-benzylphenyl)methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
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C24H24N2O3
|
1
|
| 1 |
IC50 = 120 nM
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CP0416184
|
2-[5-fluoro-2-methyl-3-[1-oxo-2-(4,4,4-trifluorobutyl)-5,6,7,8-tetrahydroisoquinolin-4-yl]indol-1-yl]acetic acid
Show/Hide
|
C24H24F4N2O3
|
1
|
| 1 |
IC50 = 123 nM
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CP0129251
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2-[6-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyridin-4-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 = 123 nM
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CP0053335
|
2-[3-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-fluoroindazol-1-yl]acetic acid
Show/Hide
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C23H21F4N3O3
|
1
|
| 1 |
IC50 = 127 nM
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CP0057091
|
2-(5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl)acetic acid
Show/Hide
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C21H17FN2O2
|
1
|
| 1 |
IC50 = 130 nM
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CP0883083
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[1-(4-Chloro-3-methoxy-benzenesulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid
Show/Hide
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C17H15ClN2O5S
|
2
|
| 1 |
IC50 = 131 nM
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| 2 |
Ki = 64 nM
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CP0414807
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H19N3O3
|
1
|
| 1 |
IC50 = 134 nM
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CP0381474
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-2-methyl-5-methylsulfonylindol-1-yl]acetic acid
Show/Hide
|
C23H21N3O5S
|
1
|
| 1 |
IC50 = 135 nM
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CP0494307
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2-[1-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-6-methoxypyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H24F3N3O4
|
1
|
| 1 |
IC50 = 135 nM
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CP0499199
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2-[5-fluoro-2-methyl-3-[(6-oxo-1-propan-2-ylpyridin-3-yl)methyl]indol-1-yl]acetic acid
Show/Hide
|
C20H21FN2O3
|
1
|
| 1 |
IC50 = 137 nM
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CP0501520
|
US9000044, 58
Show/Hide
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C19H16FNO4S
|
2
|
| 1 |
IC50 = 139 nM
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| 2 |
IC50 = 1120 nM
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CP0883082
|
[1-(4-Cyano-3-methoxy-benzenesulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid
Show/Hide
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C18H15N3O5S
|
2
|
| 1 |
IC50 = 143 nM
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| 2 |
Ki = 43 nM
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CP0379870
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2-[2-methyl-1-[(4-nitrophenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
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C17H15N3O4
|
2
|
| 1 |
IC50 = 144 nM
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|
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| 2 |
Ki = 147 nM
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CP0513123
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2-[5-chloro-2-methyl-3-[6-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]indol-1-yl]acetic acid
Show/Hide
|
C18H14ClF3N2O3
|
1
|
| 1 |
IC50 = 148 nM
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CP0554084
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2-[5-fluoro-2-methyl-3-[[6-oxo-1-(4,4,4-trifluorobutyl)pyridin-3-yl]methyl]indol-1-yl]acetic acid
Show/Hide
|
C21H20F4N2O3
|
1
|
| 1 |
IC50 = 150 nM
|
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CP0494308
|
2-[6-methyl-1-[4-methyl-2-[(5-methyltriazol-1-yl)methyl]phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C21H21N5O2
|
1
|
| 1 |
IC50 = 150 nM
|
|
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CP0245256
|
2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid
Show/Hide
|
C16H12F2N2O4S
|
2
|
| 1 |
IC50 = 150 nM
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|
|
| 2 |
Ki = 33 nM
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CP0566838
|
2-[8-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]imidazo[1,2-a]pyridin-6-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 = 159 nM
|
|
|
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CP0102785
|
2-[2-[[2-(benzenesulfonyl)phenyl]methyl]-3-methyl-5-oxo-1H-pyrazol-4-yl]acetic acid
Show/Hide
|
C19H18N2O5S
|
1
|
| 1 |
IC50 = 160 nM
|
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CP0551828
|
2-[4-[[2-(benzenesulfonyl)-5-fluorophenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C25H21FN2O4S
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
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CP0248108
|
2-[1-[2-[[[2-(dimethylamino)acetyl]-ethylamino]methyl]-4-(trifluoromethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H27F3N4O3
|
1
|
| 1 |
IC50 = 163 nM
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CP0377112
|
2-(1-(3-cyano-4-fluorophenylsulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid
Show/Hide
|
C17H12FN3O4S
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2
|
| 1 |
IC50 = 168 nM
|
|
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| 2 |
Ki = 37 nM
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CP0559111
|
2-[1-[4-chloro-2-[(4-propan-2-ylpyrimidin-5-yl)methyl]phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C24H23ClN4O2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0448172
|
2-[3-[[4-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H22N2O5S
|
1
|
| 1 |
IC50 = 170 nM
|
|
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CP0542924
|
2-[1-[(3,4-dichlorophenyl)methyl]-2-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C17H14Cl2N2O2
|
2
|
| 1 |
IC50 = 171 nM
|
|
|
| 2 |
Ki = 90 nM
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CP0447845
|
2-[2-methyl-1-[[4-(trifluoromethyl)phenyl]methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C18H15F3N2O2
|
2
|
| 1 |
IC50 = 178 nM
|
|
|
| 2 |
Ki = 122 nM
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CP0469027
|
2-[3-(2-benzyl-1-oxo-5,6,7,8-tetrahydroisoquinolin-4-yl)-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C27H25FN2O3
|
1
|
| 1 |
IC50 = 192 nM
|
|
|
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CP0514378
|
2-[5-chloro-2-methyl-3-(6-oxo-1-propan-2-ylpyridin-3-yl)indol-1-yl]acetic acid
Show/Hide
|
C19H19ClN2O3
|
1
|
| 1 |
IC50 = 195 nM
|
|
|
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CP0433068
|
2-[4-[[2-(4-methoxyphenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H24N2O5S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0435081
|
2-[4-[[2-(3-fluorophenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C25H21FN2O4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
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CP0500971
|
2-[5-methyl-4-[[2-(2-methylphenyl)sulfonylphenyl]methyl]-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H24N2O4S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
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CP0363009
|
2-[3,5-dimethyl-1-[3-[[(1S,2S)-2-phenylcyclopropanecarbonyl]amino]phenyl]pyrazol-4-yl]acetic acid
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0529571
|
2-[4-[[2-(3-chlorophenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C25H21ClN2O4S
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0459596
|
2-[3-[[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H29N3O4
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0516326
|
2-[2-methyl-3-[[2-[3-(methylcarbamoyl)phenyl]sulfonylphenyl]methyl]-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C25H25N3O6S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
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CP0381471
|
2-[3-(1-benzyl-6-oxopyridazin-3-yl)-7-chloro-5-fluoro-2-methylindol-1-yl]acetic acid
Show/Hide
|
C22H17ClFN3O3
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0413110
|
2-[4-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyridin-6-yl]acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 = 247 nM
|
|
|
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CP0562181
|
2-[6-methyl-1-[4-methyl-2-[(2-methylimidazol-1-yl)methyl]phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C22H22N4O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
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CP0326953
|
2-[6-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]indolizin-8-yl]acetic acid
Show/Hide
|
C24H23F3N2O3
|
1
|
| 1 |
IC50 = 262 nM
|
|
|
|
CP0524976
|
2-[5-methyl-3-phenyl-4-[(2-quinolin-8-ylsulfonylphenyl)methyl]pyrazol-1-yl]acetic acid
Show/Hide
|
C28H23N3O4S
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
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CP0506312
|
2-(2-methyl-1-(4-nitrophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid
Show/Hide
|
C16H13N3O6S
|
2
|
| 1 |
IC50 = 276 nM
|
|
|
| 2 |
Ki = 48 nM
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CP0404839
|
2-[1-[bis(4-fluorophenyl)methyl]-3-pyridin-4-ylpyrazol-4-yl]acetic acid
Show/Hide
|
C23H17F2N3O2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
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CP0529569
|
2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-pyridin-4-ylpyrazol-1-yl]acetic acid
Show/Hide
|
C24H21N3O4S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0556306
|
2-[1-[bis(4-fluorophenyl)methyl]-3-(3-fluoropyridin-4-yl)-5-methylpyrazol-4-yl]acetic acid
Show/Hide
|
C24H18F3N3O2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0483679
|
US9000044, 24
Show/Hide
|
C25H17ClF2O4S
|
1
|
| 1 |
IC50 = 311.5 nM
|
|
|
|
CP0456659
|
2-[4-[[2-(3,4-dimethylphenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C27H26N2O4S
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0326951
|
2-[8-[2-[[cyclopropanecarbonyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-a]pyridin-6-yl]acetic acid
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 398 nM
|
|
|
|
CP0432058
|
3-(benzenesulfonyl)-4-[[1-(carboxymethyl)-5-methyl-3-phenylpyrazol-4-yl]methyl]benzoic acid
Show/Hide
|
C26H22N2O6S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0555216
|
(2R)-2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]propanoic acid
Show/Hide
|
C24H24N2O5S
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0432055
|
2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-(morpholine-4-carbonyl)pyrazol-1-yl]acetic acid
Show/Hide
|
C24H25N3O6S
|
1
|
| 1 |
IC50 = 440 nM
|
|
|
|
CP0456658
|
2-[4-[[2-[4-(dimethylamino)phenyl]sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C27H27N3O4S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0538349
|
2-[4-[[2-(benzenesulfonyl)-4-(trifluoromethyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H21F3N2O4S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0484727
|
2-[5-methyl-3-phenyl-4-[[2-[4-(trifluoromethoxy)phenyl]sulfonylphenyl]methyl]pyrazol-1-yl]acetic acid
Show/Hide
|
C26H21F3N2O5S
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0475954
|
2-[2-methyl-3-[(2-naphthalen-1-ylphenyl)methyl]-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C27H24N2O3
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0393508
|
2-[1-[[2-(benzenesulfonylmethyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
|
C26H24N2O4S
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0432057
|
2-[4-[[2-(3-methoxyphenyl)sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C26H24N2O5S
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0418225
|
2-[2-methyl-4-oxo-3-[(2-phenoxyphenyl)methyl]-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C23H22N2O4
|
1
|
| 1 |
IC50 = 530 nM
|
|
|
|
CP0418223
|
2-[3-[(2-ethylsulfonylphenyl)methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C19H22N2O5S
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
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CP0461304
|
2-[2-methyl-3-(6-oxo-1-propan-2-ylpyridin-3-yl)indol-1-yl]acetic acid
Show/Hide
|
C19H20N2O3
|
1
|
| 1 |
IC50 = 556 nM
|
|
|
|
CP0490611
|
2-[1-[2-(imidazol-1-ylmethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0488527
|
2-[5-fluoro-2-methyl-3-[6-(4,4,4-trifluorobutoxy)pyridin-3-yl]indol-1-yl]acetic acid
Show/Hide
|
C20H18F4N2O3
|
1
|
| 1 |
IC50 = 689 nM
|
|
|
|
CP0461303
|
2-[2-methyl-3-[6-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]indol-1-yl]acetic acid
Show/Hide
|
C18H15F3N2O3
|
1
|
| 1 |
IC50 = 711 nM
|
|
|
|
CP0483790
|
2-[4-[[2-(3,4-dimethylphenyl)sulfinylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C27H26N2O3S
|
1
|
| 1 |
IC50 = 720 nM
|
|
|
|
CP0398829
|
2-[2-methyl-4-oxo-3-[[2-(triazol-1-ylmethyl)phenyl]methyl]-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C20H21N5O3
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0418227
|
2-[3-[(2-benzoylphenyl)methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C24H22N2O4
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0467031
|
2-[1-[[2-(dimethylsulfamoyl)phenyl]methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
|
C21H23N3O4S
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0385006
|
2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-5-chloro-6-oxopyridin-3-yl]acetic acid
Show/Hide
|
C20H16ClNO5S
|
1
|
| 1 |
IC50 = 860 nM
|
|
|
|
CP0482485
|
2-[5-methyl-3-phenyl-1-(quinolin-2-ylmethyl)pyrazol-4-yl]acetic acid
Show/Hide
|
C22H19N3O2
|
1
|
| 1 |
IC50 = 870 nM
|
|
|
|
CP0459607
|
2-[2-methyl-3-[(4-methylsulfonylphenyl)methyl]-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
Show/Hide
|
C18H20N2O5S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0535651
|
2-[3-(1-benzyl-6-oxopyridazin-3-yl)-7-fluoro-2-methyl-5-methylsulfonylindol-1-yl]acetic acid
Show/Hide
|
C23H20FN3O5S
|
1
|
| 1 |
IC50 = 934 nM
|
|
|
|
CP0417196
|
2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-5-methyl-3-oxo-2-phenylpyrazol-1-yl]acetic acid
Show/Hide
|
C25H22N2O5S
|
1
|
| 1 |
IC50 = 970 nM
|
|
|
|
CP0467866
|
2-[5-fluoro-2-methyl-3-[1-oxo-2-(2,2,2-trifluoroethyl)-5,6,7,8-tetrahydroisoquinolin-4-yl]indol-1-yl]acetic acid
Show/Hide
|
C22H20F4N2O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0481961
|
2-[1-[2-[(2-benzylpyrazol-3-yl)methyl]-4-methylphenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
Show/Hide
|
C28H26N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0404838
|
2-[1-[bis(4-fluorophenyl)methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
Show/Hide
|
C25H20F2N2O2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0555844
|
2-[5-methyl-3-phenyl-4-[[2-[3-(trifluoromethyl)phenyl]sulfonylphenyl]methyl]pyrazol-1-yl]acetic acid
Show/Hide
|
C26H21F3N2O4S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0540454
|
2-[2,5-dimethyl-3-[6-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]indol-1-yl]acetic acid
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C19H17F3N2O3
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1
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| 1 |
IC50 = 1120 nM
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CP0433631
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2-[1-[(2-benzoylphenyl)methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
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C26H22N2O3
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1
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| 1 |
IC50 = 1400 nM
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CP0431420
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2-[1-[4-chloro-2-(pyrimidin-5-ylmethyl)phenyl]-6-methylpyrrolo[2,3-b]pyridin-3-yl]acetic acid
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C21H17ClN4O2
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1
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| 1 |
IC50 = 1400 nM
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CP0409880
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2-[5-methoxy-3-methyl-1-[3-[[(1S,2S)-2-phenylcyclopropanecarbonyl]amino]phenyl]pyrazol-4-yl]acetic acid
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C23H23N3O4
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1
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| 1 |
IC50 = 1600 nM
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CP0514224
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2-[1-(3,4-dichlorophenyl)sulfonyl-5-methyl-3-phenylpyrazol-4-yl]acetic acid
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C18H14Cl2N2O4S
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1
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| 1 |
IC50 = 1600 nM
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CP0529570
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2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-3,5-dimethylpyrazol-1-yl]acetic acid
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C20H20N2O4S
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1
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| 1 |
IC50 = 1600 nM
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CP0455582
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]-2,2-dioxo-[1,2,5]thiadiazolo[3,4-b]pyridin-1-yl]acetic acid
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C20H17N3O6S2
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1
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| 1 |
IC50 = 1600 nM
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CP0496599
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5,7-dichloro-2-methylindol-1-yl]acetic acid
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C22H17Cl2N3O3
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1
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| 1 |
IC50 = 1690 nM
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CP0428208
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2-[6-methyl-1-[2-(triazol-1-ylmethyl)phenyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
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C19H17N5O2
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1
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| 1 |
IC50 = 1800 nM
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CP0514225
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2-[1-[(4-fluorophenyl)methyl]-5-methyl-3-pyridin-4-ylpyrazol-4-yl]acetic acid
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C18H16FN3O2
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1
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| 1 |
IC50 = 1900 nM
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CP0224659
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2-[5-methyl-1-[(2-phenoxyphenyl)methyl]-3-phenylpyrazol-4-yl]acetic acid
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C25H22N2O3
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1
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| 1 |
IC50 = 2000 nM
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CP0524978
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2-[4-[[3-(benzenesulfonyl)pyridin-4-yl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
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C24H21N3O4S
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1
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| 1 |
IC50 = 2000 nM
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CP0458488
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2-[5-methoxy-2-methyl-3-[6-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]indol-1-yl]acetic acid
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C19H17F3N2O4
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1
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| 1 |
IC50 = 2000 nM
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CP0432056
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2-[4-[[2-(3,4-dimethylphenyl)sulfanylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
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C27H26N2O2S
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1
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| 1 |
IC50 = 2300 nM
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CP0420405
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2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-5-oxo-3-phenyl-1,2,4-triazol-4-yl]acetic acid
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C23H19N3O5S
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1
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| 1 |
IC50 = 2400 nM
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CP0550025
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2-[4-[[2-(benzenesulfonyl)-4-methoxycarbonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
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C27H24N2O6S
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1
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| 1 |
IC50 = 2500 nM
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CP0379514
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2-[3-[2-[(4-cyclopropyl-1,3-oxazol-5-yl)methyl]-4-(trifluoromethyl)phenyl]-5-fluoroindol-1-yl]acetic acid
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C24H18F4N2O3
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1
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| 1 |
IC50 = 2600 nM
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CP0409850
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2-[1-[1-[2-(benzenesulfonyl)phenyl]ethyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
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C26H24N2O4S
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1
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| 1 |
IC50 = 2900 nM
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CP0385004
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2-[3-[[2-(benzenesulfonyl)phenyl]methyl]imidazo[1,5-a]pyridin-1-yl]acetic acid
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C22H18N2O4S
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1
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| 1 |
IC50 = 3000 nM
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CP0380454
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2-[5-methyl-4-[[2-(4-methylsulfonylphenyl)sulfonylphenyl]methyl]-3-phenylpyrazol-1-yl]acetic acid
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C26H24N2O6S2
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1
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| 1 |
IC50 = 4000 nM
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CP0418226
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2-[3-[[2-(benzenesulfonyl)-6-methoxyphenyl]methyl]-2-methyl-4-oxo-6,7-dihydro-5H-pyrrolo[3,2-c]pyridin-1-yl]acetic acid
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C24H24N2O6S
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1
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| 1 |
IC50 = 4500 nM
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CP0409848
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2-(5-methyl-3-phenyl-1-quinolin-4-ylpyrazol-4-yl)acetic acid
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C21H17N3O2
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1
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| 1 |
IC50 = 5000 nM
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CP0409851
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2-[1-[(4-fluoro-2-piperazin-1-ylsulfonylphenyl)methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
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C23H25FN4O4S
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1
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| 1 |
IC50 = 5000 nM
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CP0477322
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2-[3,5-dimethyl-1-[(4-methylsulfonylphenyl)methyl]pyrazol-4-yl]acetic acid
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C15H18N2O4S
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1
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| 1 |
IC50 = 5000 nM
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CP0477466
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2-[5-methyl-3-phenyl-1-[(2-phenylphenyl)methyl]pyrazol-4-yl]acetic acid
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C25H22N2O2
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1
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| 1 |
IC50 = 5000 nM
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CP0556305
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2-[1-[(4-fluorophenyl)-(4-methylsulfonylphenyl)methyl]-5-methyl-3-phenylpyrazol-4-yl]acetic acid
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C26H23FN2O4S
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1
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| 1 |
IC50 = 5000 nM
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CP0457369
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2-[4-[[2-(benzenesulfonyl)phenyl]methyl]-3-(2,5-dichlorophenyl)-5-methylpyrazol-1-yl]acetic acid
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C25H20Cl2N2O4S
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1
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| 1 |
IC50 = 5000 nM
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CP0524977
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2-[4-[[2-[3-(dimethylcarbamoyl)phenyl]sulfonylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
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C28H27N3O5S
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1
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| 1 |
IC50 = 5000 nM
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CP0538348
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2-[4-[[2-(3-methoxyphenyl)sulfanylphenyl]methyl]-5-methyl-3-phenylpyrazol-1-yl]acetic acid
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C26H24N2O3S
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1
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| 1 |
IC50 = 5000 nM
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CP0385008
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2-[3-[[2-(4-fluorophenyl)sulfonylphenyl]methyl]-4-methyl-2-oxo-5-phenylimidazol-1-yl]acetic acid
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C25H21FN2O5S
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1
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| 1 |
IC50 = 10000 nM
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CP0454944
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2-[1-[[2-(benzenesulfonyl)phenyl]methyl]-6-oxopyridin-3-yl]acetic acid
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C20H17NO5S
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1
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| 1 |
IC50 = 10000 nM
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CP0272414
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US11149018, Example 34
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C26H27BrClN3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0388823
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2-benzyl-4-[2-methyl-1-(2H-tetrazol-5-yl)indol-3-yl]phthalazin-1-one
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C25H19N7O
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1
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| 1 |
IC50 > 1000 nM
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CP0388824
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2-benzyl-4-[2-methyl-1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]phthalazin-1-one
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C30H28N4O2
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1
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| 1 |
IC50 > 1000 nM
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CP0406571
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3-[3-(3-benzyl-4-oxophthalazin-1-yl)-2-methylindol-1-yl]propanoic acid
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C27H23N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0462006
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2-[3-(3-benzyl-4-oxophthalazin-1-yl)-2-methylindol-1-yl]acetamide
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C26H22N4O2
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1
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| 1 |
IC50 > 1000 nM
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CP0499910
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2-[3-(3-benzyl-4-oxophthalazin-1-yl)-2-methylindol-1-yl]propanoic acid
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C27H23N3O3
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1
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| 1 |
IC50 > 1000 nM
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CP0499911
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2-benzyl-4-[1-(2-hydroxyethyl)-2-methylindol-3-yl]phthalazin-1-one
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C26H23N3O2
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1
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| 1 |
IC50 > 1000 nM
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CP0520622
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2-[3-(3-benzyl-4-oxophthalazin-1-yl)-2-methylindol-1-yl]-N-methylsulfonylacetamide
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C27H24N4O4S
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1
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| 1 |
IC50 > 1000 nM
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CP0524935
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2-[3-(3-benzyl-4-oxophthalazin-1-yl)-2-methylindol-1-yl]-N,N-dimethylacetamide
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C28H26N4O2
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1
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| 1 |
IC50 > 1000 nM
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CP0569461
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-5-fluoro-2-methyl-7-methylsulfonylindol-1-yl]acetic acid
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C23H20FN3O5S
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1
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| 1 |
IC50 > 1000 nM
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CP0381472
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2-[3-(1-benzyl-6-oxopyridazin-3-yl)-7-bromo-2-methylindol-1-yl]acetic acid
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C22H18BrN3O3
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1
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| 1 |
IC50 > 2000 nM
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CP0439892
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2-[3-[[1-[(2,3-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]-N,N-dimethylacetamide
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C26H24F3N3O2
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1
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| 1 |
IC50 > 2000 nM
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CP0442613
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methanesulfonamido 2-[3-[[1-[(2,3-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetate
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C25H22F3N3O5S
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1
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| 1 |
IC50 > 2000 nM
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CP0467865
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(2S)-2-[3-[[1-[(2,3-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]propanoic acid
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C25H21F3N2O3
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1
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| 1 |
IC50 > 2000 nM
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CP0526537
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(2R)-2-[3-[[1-[(2,3-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]propanoic acid
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C25H21F3N2O3
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1
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| 1 |
IC50 > 2000 nM
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CP0540453
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1-[(2,3-difluorophenyl)methyl]-5-[[5-fluoro-2-methyl-1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]methyl]pyridin-2-one
Show/Hide
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C28H26F3N3O2
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1
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| 1 |
IC50 > 2000 nM
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CP0573252
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2-[3-[[1-[(2,3-difluorophenyl)methyl]-6-oxopyridin-3-yl]methyl]-5-fluoro-2-methylindol-1-yl]acetamide
Show/Hide
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C24H20F3N3O2
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1
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| 1 |
IC50 > 2000 nM
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CP0433630
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2-[3,5-dimethyl-1-(quinolin-2-ylmethyl)pyrazol-4-yl]acetic acid
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C17H17N3O2
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1
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| 1 |
IC50 > 5000 nM
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